HOME >> BIOLOGY >> NEWS
Problem forgetting may be a natural mechanism gone awry

the brain circuits and make them ready to be used the next day. However, this mechanism in excess may lead to rapid forgetting as seen during brain aging.

Fosters lab group used aged and young rats to examine the relationships between LTD, aging and memory. The animals were trained to find a hidden platform to climb out of a pool of water - something they learned quickly with repetition.

When the researchers examined the animals neurons and used a slow, weak electrical signal to make the synapses less sensitive - an effort to squelch or depress the cellular communication - he found that the samples from younger animals and older animals that had the highest memory scores throughout their lives were more resistant to the interference. However, aged animals with impaired memories displayed what was termed as robust long-term depression.

Going back to the phone call example, not only did the rest of the room get quieter, the callers did, too. The assumption is if a memory is encoded by making synapses stronger, then memory can be disrupted by something that weakens those connections.

When we see someone we know or perhaps even ourselves becoming more forgetful, we now know that this is not an inevitable process, Foster said. Further, as we begin to understand the mechanisms of memory, it becomes possible to predict promising targets for therapeutic strategies aimed at postponing or alleviating age-related memory impairment.

Foster said it will be important to understand whether a change in cellular signaling is necessary to enable new memories to be formed by discarding old ones.

The basic gist is that information storage requires a balance between mechanisms that make synapses stronger and weaker, said Mark F. Bear, Ph.D., director of the Picower Institute for Learning and Memory at the Massachusetts Institute of Technology, who was not involved with the research. In aging and disease, if that balance is dis
'"/>

Contact: April Birdwell
afrawley@ufl.edu
352-273-5817
University of Florida
19-Feb-2007


Page: 1 2 3

Related biology news :

1. Type 2 diabetes: Problems in the furnace
2. Innovative research technique reveals another natural wonder in Yellowstone Park
3. Researchers witness natural selection at work in dramatic comeback of male butterflies
4. Sundried tide -- silent, natural disaster
5. Eavesdropping comes naturally to young song sparrows
6. Academy paleontologist and Alaska artist in line for natural history awards
7. Slow but sure -- Burned forest lands regenerate naturally
8. Life-long learning -- nature provides natural inspiration for education
9. Targeting tumors the natural way
10. New research finds that a natural family planning method is as effective as the contraceptive pill
11. Hidden-hero microbes in soil, water may help naturally clean toxic sites

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/9/2017)... VIEW, Calif. , March 9, 2017 ... 23andMe , the leading personal genetics company, are using ... now provide customers with personalized nutrition plans that consider ... but also genetic markers impacting how their body may ... food decision support platform uses biometrics such as Body ...
(Date:3/2/2017)... Summary This report provides all ... and its partnering interests and activities since 2010. ... The Partnering Deals and Alliance since 2010 report provides ... of the world,s leading life sciences companies. ... ensure inclusion of the most up to date deal ...
(Date:2/28/2017)... Germany , February 28, 2017 News ... ... Amsterdam from 14 to 16 March, Materna ... destination, and show how seamless travel is a real benefit for ... has added biometrics to their passenger touch point solutions to take ...
Breaking Biology News(10 mins):
(Date:3/28/2017)... Calif. , March 28, 2017 ... of international life sciences corporation Anpac Bio-Medical ... set a new, international record, processing and reporting ... "Cancer Differentiation Analysis" (CDA) liquid biopsy ... World Nobel Prize Laureate Summit publications, Anpac Bio,s ...
(Date:3/28/2017)... ... 2017 , ... LabKey and collaborator Just Biotherapeutics, Inc. (Just) ... LabKey Biologics . Built in collaboration with Just and designed with input from ... research teams tools for biological entity registration, assay data integration, and workflow management ...
(Date:3/28/2017)... , March 28, 2017 ... volatile and unpredictable sector due to the scientifically ... served include medical, agricultural, environmental, and industrial. In today,s ... stocks: Portola Pharmaceuticals Inc. (NASDAQ: PTLA), OvaScience Inc. ... Ocular Therapeutix Inc. (NASDAQ: OCUL ). ...
(Date:3/28/2017)... 2017 /PRNewswire/ -RepliCel Life Sciences Inc. (OTCQB: REPCF) (TSXV: RP) ... safety and clinical data from its phase 1/2 tendon repair ... follicle-derived fibroblasts (RCT-01) as a treatment for Achilles tendinosis. ... The ... profile at 6 months and showed no serious adverse events ...
Breaking Biology Technology:
Cached News: