HOME >> BIOLOGY >> NEWS
Problem forgetting may be a natural mechanism gone awry

the brain circuits and make them ready to be used the next day. However, this mechanism in excess may lead to rapid forgetting as seen during brain aging.

Fosters lab group used aged and young rats to examine the relationships between LTD, aging and memory. The animals were trained to find a hidden platform to climb out of a pool of water - something they learned quickly with repetition.

When the researchers examined the animals neurons and used a slow, weak electrical signal to make the synapses less sensitive - an effort to squelch or depress the cellular communication - he found that the samples from younger animals and older animals that had the highest memory scores throughout their lives were more resistant to the interference. However, aged animals with impaired memories displayed what was termed as robust long-term depression.

Going back to the phone call example, not only did the rest of the room get quieter, the callers did, too. The assumption is if a memory is encoded by making synapses stronger, then memory can be disrupted by something that weakens those connections.

When we see someone we know or perhaps even ourselves becoming more forgetful, we now know that this is not an inevitable process, Foster said. Further, as we begin to understand the mechanisms of memory, it becomes possible to predict promising targets for therapeutic strategies aimed at postponing or alleviating age-related memory impairment.

Foster said it will be important to understand whether a change in cellular signaling is necessary to enable new memories to be formed by discarding old ones.

The basic gist is that information storage requires a balance between mechanisms that make synapses stronger and weaker, said Mark F. Bear, Ph.D., director of the Picower Institute for Learning and Memory at the Massachusetts Institute of Technology, who was not involved with the research. In aging and disease, if that balance is dis
'"/>

Contact: April Birdwell
afrawley@ufl.edu
352-273-5817
University of Florida
19-Feb-2007


Page: 1 2 3

Related biology news :

1. Type 2 diabetes: Problems in the furnace
2. Innovative research technique reveals another natural wonder in Yellowstone Park
3. Researchers witness natural selection at work in dramatic comeback of male butterflies
4. Sundried tide -- silent, natural disaster
5. Eavesdropping comes naturally to young song sparrows
6. Academy paleontologist and Alaska artist in line for natural history awards
7. Slow but sure -- Burned forest lands regenerate naturally
8. Life-long learning -- nature provides natural inspiration for education
9. Targeting tumors the natural way
10. New research finds that a natural family planning method is as effective as the contraceptive pill
11. Hidden-hero microbes in soil, water may help naturally clean toxic sites

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/15/2016)... , April 15, 2016  A new partnership ... more accurate underwriting decisions in a fraction of ... competitively priced and high-value life insurance policies to ... With Force Diagnostics, rapid testing (A1C, ... data readings (blood pressure, weight, pulse, BMI, and ...
(Date:3/31/2016)...  Genomics firm Nabsys has completed a financial  restructuring ... , M.D., who returned to the company in October ... team, including Chief Technology Officer, John Oliver , ... and Vice President of Software and Informatics, Michael ... Dr. Bready served as CEO of Nabsys from 2005-2014 ...
(Date:3/21/2016)... 22, 2016 Unique technology ... for superior security   Xura, ... of secure digital communications services, today announced it is ... offer enterprise customers, particularly those in the Financial Services ... voice authentication within a mobile app, alongside, and in ...
Breaking Biology News(10 mins):
(Date:5/25/2016)... ... May 25, 2016 , ... The ... by the Office of the National Coordinator for Health IT (ONC) outlining a ... clinically relevant data were available when and where it was needed. The organization ...
(Date:5/25/2016)... , ... May 25, 2016 , ... WEDI, the nation’s ... exchange, today announced that Charles W. Stellar has been named by the WEDI Board ... since January 2016. As an executive leader with more than 35 years of experience ...
(Date:5/25/2016)... ... May 25, 2016 , ... ... and Drug Administration (FDA) has granted the company’s orphan drug designation request covering ... orphan drug designation granted by the FDA. , Spinocerebellar ataxia is a ...
(Date:5/24/2016)... Israel , May 24, 2016   MedyMatch Technology ... physicians with artificial intelligence, real-time decision support tools in the ... present at the 2016 Israeli Advanced Technology Industries (IATI) BioMed ... Israel,s 15th National Life Sciences and ... at the David Intercontinental Hotel in Tel Aviv, ...
Breaking Biology Technology:
Cached News: