HOME >> BIOLOGY >> NEWS
Problem forgetting may be a natural mechanism gone awry

the brain circuits and make them ready to be used the next day. However, this mechanism in excess may lead to rapid forgetting as seen during brain aging.

Fosters lab group used aged and young rats to examine the relationships between LTD, aging and memory. The animals were trained to find a hidden platform to climb out of a pool of water - something they learned quickly with repetition.

When the researchers examined the animals neurons and used a slow, weak electrical signal to make the synapses less sensitive - an effort to squelch or depress the cellular communication - he found that the samples from younger animals and older animals that had the highest memory scores throughout their lives were more resistant to the interference. However, aged animals with impaired memories displayed what was termed as robust long-term depression.

Going back to the phone call example, not only did the rest of the room get quieter, the callers did, too. The assumption is if a memory is encoded by making synapses stronger, then memory can be disrupted by something that weakens those connections.

When we see someone we know or perhaps even ourselves becoming more forgetful, we now know that this is not an inevitable process, Foster said. Further, as we begin to understand the mechanisms of memory, it becomes possible to predict promising targets for therapeutic strategies aimed at postponing or alleviating age-related memory impairment.

Foster said it will be important to understand whether a change in cellular signaling is necessary to enable new memories to be formed by discarding old ones.

The basic gist is that information storage requires a balance between mechanisms that make synapses stronger and weaker, said Mark F. Bear, Ph.D., director of the Picower Institute for Learning and Memory at the Massachusetts Institute of Technology, who was not involved with the research. In aging and disease, if that balance is dis
'"/>

Contact: April Birdwell
afrawley@ufl.edu
352-273-5817
University of Florida
19-Feb-2007


Page: 1 2 3

Related biology news :

1. Type 2 diabetes: Problems in the furnace
2. Innovative research technique reveals another natural wonder in Yellowstone Park
3. Researchers witness natural selection at work in dramatic comeback of male butterflies
4. Sundried tide -- silent, natural disaster
5. Eavesdropping comes naturally to young song sparrows
6. Academy paleontologist and Alaska artist in line for natural history awards
7. Slow but sure -- Burned forest lands regenerate naturally
8. Life-long learning -- nature provides natural inspiration for education
9. Targeting tumors the natural way
10. New research finds that a natural family planning method is as effective as the contraceptive pill
11. Hidden-hero microbes in soil, water may help naturally clean toxic sites

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/5/2017)... NEW YORK , April 5, 2017 ... security, is announcing that the server component of the ... is known for providing the end-to-end security architecture that ... customers. HYPR has already secured over 15 ... system makers including manufacturers of connected home product suites ...
(Date:3/30/2017)... 2017  On April 6-7, 2017, Sequencing.com will host ... hackathon at Microsoft,s headquarters in Redmond, ... on developing health and wellness apps that provide a ... Genome is the first hackathon for personal genomics ... companies in the genomics, tech and health industries are ...
(Date:3/28/2017)... 2017 The report "Video Surveillance ... Servers, Storage Devices), Software (Video Analytics, VMS), and Service ... Forecast to 2022", published by MarketsandMarkets, the market was ... projected to reach USD 75.64 Billion by 2022, at ... base year considered for the study is 2016 and ...
Breaking Biology News(10 mins):
(Date:10/12/2017)... ... October 12, 2017 , ... BioMedGPS ... the addition of its newest module, US Hemostats & Sealants. , SmartTRAK’s US ... absorbable hemostats, fibrin sealants, synthetic sealants and biologic sealants used in surgical applications. ...
(Date:10/11/2017)... ... October 11, 2017 , ... The CRISPR-Cas9 system ... experiments and avoiding the use of exogenous expression plasmids. The simplicity of programming ... systematic gain-of-function studies. , This complement to loss-of-function studies, such as with ...
(Date:10/11/2017)... 2017  VMS BioMarketing, a leading provider of patient support ... Nurse Educator (CNE) network, which will launch this week. The ... health care professionals to enhance the patient care experience by ... other health care professionals to help women who have been ... ...
(Date:10/11/2017)... ... 11, 2017 , ... Singh Biotechnology today announced that the ... its novel anti-STAT3 (Signal Transducer and Activator of Transcription 3) B VHH13 single ... the cell membrane and bind intracellular STAT3 and inhibit its function. Dysregulation of ...
Breaking Biology Technology:
Cached News: