Profiling amniotic fluid yields faster test for infection and preterm birth risk, researchers find

Researchers at the 26th Annual Society for Maternal-Fetal Medicine (SMFM) meeting today announced that profiling certain proteins in amniotic fluid is the fastest and most accurate way to detect potentially dangerous infections in pregnant women, and also can accurately predict whether premature delivery is imminent.

Diagnosing intra-amniotic inflammation or infection is crucial because these conditions can lead to the death of the fetus or other serious consequences of preterm birth, including brain damage, lung and bowel injury.

The study's authors were recognized by an award from the March of Dimes, marking the third year that the organization has honored SMFM members for cutting-edge prematurity research. The March of Dimes is conducting a multi-year, multi-million-dollar campaign aimed at reducing the growing rate of premature births through research and awareness.

"Our goal was to create a test that could more accurately predict which pregnancies with preterm labor are at risk for fetal complications from intrauterine inflammation/infection," said Catalin S. Buhimschi, M.D., of Yale University, the lead study author and SMFM member. "We found that profiling the proteins in amniotic fluid for markers of inflammation--a proteomic profile--not only yielded results twice as fast as other tests, but those results were also much more accurate. We discovered that the presence of fewer than two biomarkers for inflammation meant the median time for delivery was five to six days. If all the biomarkers for inflammation were present, delivery time was within hours."

"Research such as this is vital if we are to understand the basic mechanisms underlying preterm birth and find ways to prevent or treat it," said Nancy S. Green, M.D., medical director of the March of Dimes. "Dr. Buhimschi's work is exciting because it offers a potential new tool to identify women who are at highest risk for a preterm delivery. For these women, knowing the

Contact: Sanda Pecina
March of Dimes Birth Defects Foundation

Page: 1 2

Related biology news :

1. Profiling of cancer genes may lead to better and earlier detection
2. Molecular Profiling Institute, Inc. acquires NanoBiomics, Inc.
3. The Molecular Profiling Institute, Inc. launches MammaPrint for breast cancer patients
4. The Molecular Profiling Institute named US provider of genetic breast cancer test
5. New proteomic method to detect inflammation in amniotic fluid
6. Cells from amniotic fluid used to tissue-engineer a new trachea
7. Protein analysis of amniotic fluid reveals clues about preterm birth
8. Researchers find new technique to identify fetal genetic material from amniotic fluid
9. Antibody linked to MS significantly higher in spinal fluid of blacks
10. Research on microfluidics widens the possibilities for electronic devices
11. Laser goes tubing for faster body-fluid tests

Post Your Comments:

(Date:10/29/2015)... 29, 2015 Daon, a global leader in ... released a new version of its IdentityX Platform ... North America have already installed IdentityX v4.0 ... a FIDO UAF certified server component as ... activate FIDO features. These customers include some of the ...
(Date:10/27/2015)... 2015 In the present market scenario, security ... various industry verticals such as banking, healthcare, defense, electronic ... demand for secure & simplified access control and growing ... hacking of bank accounts, misuse of users, , and ... PC,s, laptops, and smartphones are expected to provide potential ...
(Date:10/26/2015)... 26, 2015  Delta ID Inc., a company focused ... and PC devices, announced its ActiveIRIS® technology powers the ... F-02H launched by NTT DOCOMO, INC in ... second smartphone to include iris recognition technology, after a ... F-04G in May 2015, world,s first smartphone to have ...
Breaking Biology News(10 mins):
(Date:11/24/2015)... --> --> ... by Transparency Market Research, the global non-invasive prenatal testing ... 17.5% during the period between 2014 and 2022. The ... Analysis, Size, Volume, Share, Growth, Trends and Forecast 2014 ... to reach a valuation of US$2.38 bn by 2022. ...
(Date:11/24/2015)... , Nov. 24, 2015 /PRNewswire/ - Aeterna Zentaris ... today that the remaining 11,000 post-share consolidation (or ... Warrants (the "Series B Warrants") subject to the ... on November 23, 2015, which will result in ... giving effect to the issuance of such shares, ...
(Date:11/24/2015)... Switzerland (PRWEB) , ... November 24, 2015 , ... ... plant and the environment are paramount. Insertion points for in-line sensors can represent ... has developed the InTrac 781/784 series of retractable sensor housings , which ...
(Date:11/24/2015)... ... November 24, 2015 , ... Creation Technologies ... being named to Deloitte's 2015 Technology Fast 500 list of the fastest growing ... a FDA-cleared, Class II medical device that speeds up orthodontic tooth movement by ...
Breaking Biology Technology:
Cached News: