HOME >> BIOLOGY >> NEWS
Profiling of cancer genes may lead to better and earlier detection

ically in the tumor samples.

"We ended up with a large number of genes that are involved in the development of lung cancer that, despite years of work in the field, I had never connected to lung cancer before," said Dr. Minna.

Patient samples from UT Southwestern's new Harold C. Simmons Comprehensive Cancer Center tissue repository and previous results from study author Dr. David Euhus allowed the research team to quickly extend its findings to breast, prostate and colon cancer. A Hamon Center postdoctoral researcher and lead study author Dr. David Shames was instrumental in identifying the genes, Dr. Minna said.

"What would have normally taken us several years, David Shames was able to determine in less than a month," Dr. Minna said. "The new genes Dr. Shames discovered are now forming the basis for a new early detection screen that could be mounted against the most common human cancers."

The genes the researchers found to be methylated specifically in the tumor samples might control the conversion of normal cells into cancer cells, Dr. Minna said, but this possibility needs to be tested on a case-by-case basis.

Although it is known that gene expression patterns in tumors vary greatly from tissue to tissue, the researchers hope that the similarities of the methylation patterns found in this study might lead to a better approach to detect cancer early and help identify new promising therapeutic targets to treat some of the most prevalent cancers.

"The findings from our study suggest that it may be possible to develop a methylation profiling platform that could be used to screen patients for common solid tumors, while at the same time identify what type of tumor the patient may have," Dr. Shames said.

The study also illustrates that some of the basic processes that underlie the development of breast and lung cancer are identical, even though the chemicals that initiate those processes estrogen
'"/>

Contact: Toni Heinzl
Toni.Heinzl@utsouthwestern.edu
214-648-3404
UT Southwestern Medical Center
25-Dec-2006


Page: 1 2 3

Related biology news :

1. Profiling amniotic fluid yields faster test for infection and preterm birth risk, researchers find
2. Molecular Profiling Institute, Inc. acquires NanoBiomics, Inc.
3. The Molecular Profiling Institute, Inc. launches MammaPrint for breast cancer patients
4. The Molecular Profiling Institute named US provider of genetic breast cancer test
5. Protein chatter linked to cancer activation
6. Newly created cancer stem cells could aid breast cancer research
7. Green tea boosts production of detox enzymes, rendering cancerous chemicals harmless
8. ESF EURYI award winner aims to stop cancer cells reading their own DNA
9. No evidence that widely prescribed statins protect against prostate cancer
10. A study by the MUHC and McGill University opens a new door to understanding cancer
11. New study suggests Concord grape juice may provide protection against breast cancer

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/5/2020)... ... June 04, 2020 , ... Murrieta Genomics ... new patent application for simplified sample preparation for Next Generation Genomic Sequencing (NGS) ... reduce cost, time, and complexity of sample preparation. , “I have been at the ...
(Date:6/2/2020)... ... June 02, 2020 , ... ... software developer and solutions provider, today reported that the implementation of browser-based, ... compliance by 100%, resulting in greater efficiency for global biotechnology company, bioMérieux. ...
(Date:5/28/2020)... , ... May 27, 2020 , ... ... Workforce Advisor™ , a solution that uniquely combines lab testing insights and ... employers systematically support the ongoing health and safety of employees returning to the ...
Breaking Biology News(10 mins):
(Date:5/21/2020)... , ... May 19, 2020 , ... Experienced periodontist in ... get dental implants and bone grafting through PIEZOSURGERY® technology. PIEZOSURGERY uses ultrasonic ... often used to prepare a patient for dental implants, especially when the implants need ...
(Date:5/21/2020)... ... May 20, 2020 , ... Exo (pronounced ... as the company’s executive vice president of product engineering and report directly to ... medical imaging space, bringing more than 24 years of technology leadership experience from ...
(Date:5/15/2020)... ... May 14, 2020 , ... ... multiple open heart surgeries before becoming adults. The reason: there are ... address this critical unmet need, the Department of Defense has awarded Draper, Boston ...
(Date:5/15/2020)... (PRWEB) , ... May 15, 2020 , ... Sentien Biotechnologies, ... appointment of Richard Ganz as Executive Chairman. Mr. Ganz will continue to lead ... as well as work closely with CEO Brian Miller and Sentien’s management team. ...
Breaking Biology Technology:
Cached News: