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Promising new research on hereditary diseases

Cambridge, MA, August 22, 2006 An international group of stellar scientists gathered together for four days of intense discussion, debate and designing future therapies for Huntington's disease and related disorders. From August 10 - 14, 2006 the Hereditary Disease Foundation convened HD 2006: Changes, Advances and Good News (CAG)n in Cambridge, Massachusetts.

Almost 400 scientists met together to share their latest discoveries. "The synergy, innovation and enthusiastic collaboration fostered by this gathering of dedicated scientists brings out the best in all of us and will hopefully lead us to a lifesaving cure for Huntington's disease!" stated Nancy S. Wexler, Ph.D., President of the Hereditary Disease Foundation and Higgins Professor of Neuropsychology in the Departments of Neurology and Psychiatry of the College of Physicians and Surgeons at Columbia University, in her opening remarks. "We are gratified that so many excellent scientists from around the world participated and presented their latest, cutting-edge and unpublished data to advance the search for a cure for Huntington's disease", said Carl D. Johnson, Ph.D., Executive Director for Science of the Hereditary Disease Foundation.

Topics covered:

  • Unraveling the cause of Huntington's disease
  • Novel therapeutic strategies
  • Advances in RNA interference therapy
  • Discovering new drugs
  • Clinical trials

Participants described the meeting as "the definitive Huntington's disease meeting in the world for this year."

Highlights of the meeting included the following:

An extremely promising innovative strategy presented involves tackling the problem at its very source. DNA in the gene causing Huntington's disease expands too much. This abnormal DNA is copied faithfully into RNA. The RNA then makes a protein which is also abnormal. This abnormal protein wreaks havoc and eventually is the cause of cellular disability an
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Contact: Lisa B. Lager
lisalager@hdfoundation.org
212-928-3073
Hereditary Disease Foundation
22-Aug-2006


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