HOME >> BIOLOGY >> NEWS
Quantum biology -- Powerful computer models reveal key biological mechanism

Troy, N.Y. -- Using powerful computers to model the intricate dance of atoms and molecules, researchers at Rensselaer Polytechnic Institute have revealed the mechanism behind an important biological reaction. In collaboration with scientists from the Wadsworth Center of the New York State Department of Health, the team is working to harness the reaction to develop a "nanoswitch" for a variety of applications, from targeted drug delivery to genomics and proteomics to sensors.

The research is part of a burgeoning discipline called "quantum biology," which taps the skyrocketing power of today's high-performance computers to precisely model complex biological processes. The secret is quantum mechanics -- the much-touted theory from physics that explains the inherent "weirdness" of the atomic realm.

Reporting in the February 2007 issue of Biophysical Journal, the researchers describe a mechanism to explain how an intein -- a type of protein found in single-celled organisms and bacteria -- cuts itself out of the host protein and reconnects the two remaining strands. The intein breaks a protein sequence at two points: first the N-terminal, and then the C-terminal. This aspect of the project, which is led by Saroj Nayak, associate professor of physics, applied physics, and astronomy at Rensselaer, focuses on the C-terminal reaction.

Another Rensselaer team previously found that the reaction at the C-terminal speeds up in acidic environments. But to control the reaction and use it as a nanoswitch, a better understanding of the mechanism behind this reaction is needed, according to Philip Shemella, a doctoral student in physics at Rensselaer and corresponding author of the current paper.

"You can use this protein that cuts itself and joins the pieces together in a predictable way," he said. "It already has a function that would be nice to harness for nanotechnology purposes." And because the reaction may be sensitive to light and o
'"/>

Contact: Jason Gorss
gorssj@rpi.edu
518-276-6098
Rensselaer Polytechnic Institute
16-Jan-2007


Page: 1 2 3

Related biology news :

1. Quantum secrets of photosynthesis revealed
2. NRC team uses new Quantum Technology to control molecules
3. Quantum dots reviewed -- Could these nanoparticles hold the cure to cancer?
4. Connect the Quantum Dots
5. Quantum dot method rapidly identifies bacteria
6. Quantum cascade lasers key to handheld gas and liquid sensors
7. Quantum dots provide a faster, more sensitive method for detecting respiratory viral infections
8. Quantum dots research leads to new knowledge about protein binding in plants
9. New textbook illuminates the close links between evolutionary and molecular biology
10. University of Leeds strengthens China links in membrane and neurobiology
11. Probing biologys dark matter

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/14/2017)... (NYSE: IBM ) is introducing several innovative partner startups ... collaboration between startups and global businesses, taking place in ... nine startups will showcase the solutions they have built with ... France is one of the ... percent increase in the number of startups created between 2012 ...
(Date:5/16/2017)... 16, 2017   Bridge Patient Portal , ... MD EMR Systems , an electronic medical ... GE, have established a partnership to build an ... the GE Centricity™ products, including Centricity Practice Solution ... These new integrations will allow healthcare delivery ...
(Date:4/19/2017)... New York , April 19, 2017 ... competitive, as its vendor landscape is marked by the ... the market is however held by five major players ... Safran. Together these companies accounted for nearly 61% of ... of the leading companies in the global military biometrics ...
Breaking Biology News(10 mins):
(Date:10/12/2017)... ... October 12, 2017 , ... ... platform specifically designed for life science researchers to analyze and interpret datasets, ... Franklin, who made a major contribution to the discovery of the double-helix ...
(Date:10/11/2017)... ... ... Personal eye wash is a basic first aid supply for any work environment, but most ... you rinse first if a dangerous substance enters both eyes? It’s one less decision, and ... unique dual eye piece. , “Whether its dirt and debris, or an acid or alkali, ...
(Date:10/11/2017)... , Oct. 11, 2017  VMS BioMarketing, a leading ... a nationwide oncology Clinical Nurse Educator (CNE) network, which will ... need for communication among health care professionals to enhance the ... nurses, office staff, and other health care professionals to help ... breast cancer. ...
(Date:10/11/2017)... ... October 11, 2017 , ... ... implantation and pregnancy rates in frozen and fresh in vitro fertilization (IVF) ... and maternal age to IVF success. , After comparing the results from the ...
Breaking Biology Technology:
Cached News: