Rate of gain, obesity factor into increased risk for prostate cancer recurrence

r risk gained an average of 1.5 kilogram per year, or about three and a half pounds per year. Thus, a man who weighed 150 pounds at age 25 but weighed over 200 pounds by age 40 would be at a higher risk for recurrence if he develops prostate cancer.

Strom's study also identified that men who were obese at age 40 had twice the likelihood of biochemical failure after surgery than non-obese men. Strom and her colleagues considered obesity to conform to the conventional medical indexing called 'body mass index,' which is a patient's weight divided by the square of his height. For example, a 200 pound man who is five-foot nine-inches tall has a body mass index of 30 and is considered obese within the guidelines of this study.

The incorporation of body mass index at time of diagnosis with other measures of prostate cancer progression, such as PSA levels prior to surgery, age, stage of progression, Gleason Score, or tumor cell invasion of lymph nodes or seminal vesicles, enhances the predictive value of tools used to determine the risk each patient has for recurrence of prostate cancer.

"Urologists and oncologists can use this information when a man is diagnosed with prostate cancer to develop treatment strategies for that patient," Strom said. "By plugging in the clinical characteristics, they calculate each patient's risk of having more aggressive disease that will progress," she noted. "Body mass index makes that information more precise."


Contact: Russell Vanderboom, Ph.D.
American Association for Cancer Research

Page: 1 2

Related biology news :

1. Clock gene plays role in weight gain, study finds
2. Think herbal supplements are safe? Think again, book by Saint Louis University doctor says
3. Study suggests estrogen deficiency can lead to obesity-induced high blood pressure after menopause
4. Monell researchers find metabolic defect in liver that can lead to obesity
5. Adult survivors of childhood leukemia exercise less, worsening high risk for obesity and illness
6. New role for protein in fat cells may improve understanding of obesity and diabetes
7. Link between obesity and enlarged heart discovered by University of Arizona researchers
8. Fat fish put obesity on the hook
9. Uncovering the molecular basis of obesity
10. Fat tissue-derived hormone leptin increases e-cadherin expression, obesity-breast cancer link noted
11. Food cue-related brain activity linked to obesity?

Post Your Comments:

(Date:11/17/2015)... EASTON, Mass. , Nov. 17, 2015 ... a leader in the development and sale of broadly ... the worldwide life sciences industry, today announced it has ... of its $5 million Private Placement (the "Offering"), increasing ... to $4,025,000.  One or more additional closings are expected ...
(Date:11/12/2015)... BOSTON , Nov. 12, 2015  A golden ... for Duchenne muscular dystrophy (DMD) has provided a new ... Boston Children,s Hospital, the Broad Institute of MIT and ... Brazil . Cell, ... some dogs "escape" the disease,s effects. The Boston Children,s ...
(Date:11/12/2015)... , Nov. 11, 2015   Growing ... reliable analytical tools has been paving the way ... qualitative determination of discrete analytes in clinical, agricultural, ... are being predominantly used in medical applications, however, ... environmental sectors due to continuous emphasis on improving ...
Breaking Biology News(10 mins):
(Date:11/23/2015)... Nov. 24, 2015 Women with a certain type ... face a higher risk of lung cancer than men with ... week at the annual meeting of the Radiological Society of ... --> --> Lung nodules are small ... solid or subsolid based on their appearance on CT. Solid ...
(Date:11/23/2015)... 2015 China Cord Blood Corporation (NYSE: ... of cord blood collection, laboratory testing, hematopoietic stem cell ... preliminary unaudited financial results for the second quarter and ... 2015. --> --> ... for the second quarter of fiscal 2016 increased by ...
(Date:11/23/2015)... Church, VA (PRWEB) , ... November 23, 2015 , ... ... Ellen McCarthy , former Director, Plans and Programs, National Geospatial Intelligence Agency (NGA), has ... to us with an incredibly distinguished career in the intelligence community and the private ...
(Date:11/23/2015)... and PISCATAWAY, New Jersey ... Cambridge Crystallographic Data Centre (CCDC) announces the ... Structural Database (CSD) and the CSD-System, now complemented ... worldwide: CSD-Discovery to support the discovery of new ... and CSD-Enterprise, the complete set of the CCDC,s ...
Breaking Biology Technology:
Cached News: