rome, and we suspect the same in the new syndrome," says Dietz. "Our studies so far support the idea that these patients' cells compensate for the problems in TGF-beta receptor 1 and 2, but in doing so overshoot what's normal. More work needs to be done to address this issue, which might offer a target for developing medical intervention for these patients."
The Johns Hopkins researchers were funded by the Howard Hughes Medical Institute, the National Heart, Lung and Blood Institute, the National Institute of Arthritis and Musculoskeletal and Skin Diseases and the National Marfan Foundation.
Authors on the paper are Loeys, Dietz, Junji Chen, Enid Neptune, Daniel Judge, Megan Podowski, Tammy Holm, Jennifer Meyers, Carmen Leitch, Nicholas Katsanis, Neda Sharifi, Lauren Xu, Loretha Myers, Philip Spevak and Duke Cameron of Johns Hopkins; Julie De Backer, Jan Hellemans, Paul Coucke and Anne De Paepe of Ghent University Hospital, Belgium; Yan Chen and Daniel Rifkin of New York University School of Medicine; Elaine Davis of McGill University, Montreal, Canada; Catherine Webb, Northwestern University School of Medicine; and Wolfram Kress, University of Wuerzburg, Germany.
Page: 1 2 3 4 Related biology news :1
Contact: Joanna Downer
Johns Hopkins Medical Institutions
. Preclinical study links gene to brain aneurysm formation2
. Study suggests other causes for childhood brain aneurysms3
. New research suggests abdominal aortic aneurysm will afflict millions of baby boomers4
. Why do aneurysms form? New studies suggest leading role for white blood cells5
. New study suggests role for clazosentan in the prevention of cerebral vasospasm after aneurysmal SAH6
. UCSD medical researchers use brain cell transplants to correct muscle spasms after aneurysm surgery7
. Estrogen protects male rats from aortic aneurysms8
. Unknotting DNA clue to cancer syndrome9
. Metabolic syndrome -- dont blame the belly fat10
. Researchers identify fifth gene responsible for Joubert syndrome11
. Fragile X syndrome -- A stimulating environment restores neuronal function in mice