Reduced frontal-lobe activity and impulsivity may be linked to alcoholism risk

Increased impulsivity, or a lack of impulse control, is a key characteristic of many psychiatric disorders, including alcohol dependence. Recent studies suggest that increased impulsivity is involved in a predisposition to developing these disorders. A new study of brain processes provides support for this theory.

Results are published in the January issue of Alcoholism: Clinical & Experimental Research.

"Altered impulsivity is a prominent manifestation in many disinhibitory psychiatric disorders, such as alcohol- or substance-related disorders, conduct disorder, attention-deficit hyperactive disorder (ADHD), antisocial personality disorder (ASP), bipolar disorder, impulse control disorders, and so on," said Bernice Porjesz, professor and director of the Henri Begleiter Neurodynamics Laboratory at SUNY Downstate Medical Center. "Individuals suffering with these disorders may frequently and unpredictably act without planning in advance or without regard to the negative consequences of their behaviors, which in turn can result in serious aftermath. In severe cases, it may lead to danger to the patient or to others."

Porjesz added that the majority of psychiatric diseases are "complex diseases," meaning that their development is influenced by an underlying biological susceptibility of genetic factors, environmental factors, and interactions among multiple genes and the environment.

"Disinhibitory disorders share many similar clinical presentations as well as similar neurobiological abnormalities such as brain waves," said Porjesz. "This suggests that this group of disorders may have some underlying genetic vulnerabilities in common that contribute to the disorders. One recent study of genetic and environmental contributions to internalizing and externalizing disorders determined that the single most important factor underlying externalizing disorders is a genetic liability involving impulse control."



Page: 1 2 3

Related biology news :

1. Reduced body temperature extends lifespan in study from the Scripps Research Institute
2. Reduced calorie and carbohydrate diet slows progression of Alzheimers disease in mouse model
3. Reduced fish stocks linked to increased bushmeat trade, wildlife declines in W. Africa
4. Prenatal alcohol exposure alters brain activity in the frontal-striatal areas
5. Genes activity points to more lethal subtype of AML
6. Weizmann Institute scientists develop a general control switch for protein activity
7. Slow wave activity during sleep is lower in African-Americans than Caucasians
8. ChemGenex announces publication confirming activity of Ceflatonin in T315I-Positive CML
9. Neuronal activity gives clues to working memory
10. CSHL links activity in brain synapses and developmental abnormalities with schizophrenia gene
11. Hyperactivity and academic achievement could be linked by genetics

Post Your Comments:

(Date:7/23/2019)... ... , ... NanoFUSE is pleased to announce the ... spine and orthopedic use. Bioactive glass is a calcium phosphate coated silica that ... orthopedics for over 30 years and now NanoFUSE Biologics has used advanced research ...
(Date:7/19/2019)... ... July 19, 2019 , ... ... and Crystalline States – Insights from Synchrotron X-ray Pair Distribution (SXPDF) Studies”. The ... with Chris Benmore of Argonne National Laboratory and Gabriel de Araujo of the ...
(Date:7/17/2019)... Pa. (PRWEB) , ... July 15, 2019 , ... ... of computational science expertise exclusively for Life Sciences and Healthcare companies, announces the ... provide critical advisory services and strategic direction to start-up and emerging bio-pharma companies ...
Breaking Biology News(10 mins):
(Date:6/11/2019)... Fla. (PRWEB) , ... June 10, 2019 , ... ... in science and technology in an upcoming episode, scheduled to broadcast 4Q/2019. Check ... the Eppendorf Group) and will educate viewers about how its technology facilitates laboratories ...
(Date:6/11/2019)... POWAY, Calif. (PRWEB) , ... June 11, 2019 ... ... parent company of Personalized Stem Cells Inc. (PSC) , has announced that ... of Public Health, Food and Drug Branch for manufacturing. This is an ...
(Date:5/31/2019)... ... May 29, 2019 , ... For many years, the primary forms of cancer ... breakthrough therapies. Advances in immuno-oncology have led to the advent of Chimeric Antigen Receptor ... T cell receptors known as “CARs”. The CAR enables the final product to produce ...
(Date:5/31/2019)... ... May 30, 2019 , ... Object ... announce the strategic acquisition of Metabiologics, Inc., a globally recognized leader in the ... ownership and commercialization rights to a full spectrum of botulinum neurotoxins, as well ...
Breaking Biology Technology:
Cached News: