HOME >> BIOLOGY >> NEWS
Research teams uncover risk genes for multiple sclerosis

d Hafler, MD, the Jack, Sadie and David Breakstone professor of neurology at Harvard Medical School and Brigham and Womens Hospital, another of the consortium study authors. This study will likely spur further research into the connection between these seemingly separate conditions.

These advances are an outgrowth of a 15-year effort at UCSF to create a national repository of more than 10,000 samples of DNA from people with MS and their families, the largest such collection nationwide. A similar database, in both quantity and quality, had been developed at the University of Cambridge, in England. Both collections were used for both of these studies.

But the real breakthroughs came through collaboration. Hauser said that individually, none of the six centers in the consortium could have completed a study of this scale and complexity, but by using a Collaborative Research Award from the National MS Society, they were able to form a truly effective international consortium that could deliver the most exhaustive search for MS risk factors ever published.

The consortium paper is among a series of recent whole-genome association studies that have begun to uncover the genetic basis of complex diseases like diabetes, schizophrenia, and coronary artery disease. Unlike diseases caused by a mutation in a single gene, these conditions seem to arise from a combination of genetic, behavioral and environmental factors.

Jorge Oksenberg, PhD, a UCSF neurology professor who has been involved in the development of the UCSF collection for more than a decade, said that it wasnt until scientists were able to combine the potential of both repositories with the intellectual and financial resources of previously competing research teams that they were able to make the connections represented in these studies.

For studying these complex genetic diseases, where were looking at many genes contributing and each one contributing just a littl
'"/>

Contact: Kristen Bole
kbole@pubaff.ucsf.edu
415-476-2557
University of California - San Francisco
30-Jul-2007


Page: 1 2 3 4

Related biology news :

1. Gilbert Foundation and American Fed for Aging Research award grants on Alzheimers disease
2. Research shows skeleton to be endocrine organ
3. Research aims to identify markers for menopausal women at risk for deadly blood clot
4. Research team enlightens the reasons for severe blindness
5. Research shows NPD1 protects a key component of vision
6. Researchers find pathway that controls cell size and division
7. Researchers watch antibiotics, bacteria meet at atomic level
8. Researchers discover gene responsible for Restless Legs Syndrome
9. Research study describes the role part of the brain plays in memory
10. NY Stem Cell Foundations 2nd Annual Translational Stem Cell Research Conference
11. Researchers witness natural selection at work in dramatic comeback of male butterflies

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/15/2016)... 15, 2016 Yissum Research Development Company ... company of the Hebrew University, announced today the formation ... technology of various human biological indicators. Neteera Technologies has ... from private investors. ... detection of electromagnetic emissions from sweat ducts, enables reliable ...
(Date:3/11/2016)... http://www.apimages.com ) - --> http://www.apimages.com ) - ... Images ( http://www.apimages.com ) - Germany . ... new refugee identity cards. DERMALOG will be unveiling this device, and ... Hanover next week.   --> Germany ... the new refugee identity cards. DERMALOG will be unveiling this device, ...
(Date:3/10/2016)... BELL, Pa. , March 10, 2016   Unisys ... U.S. Customs and Border Protection (CBP) is testing its ... San Diego to help identify certain ... States . The test, designed to help determine the ... pedestrian environment, began in February and will run until May ...
Breaking Biology News(10 mins):
(Date:4/28/2016)... ... April 28, 2016 , ... Morris Midwest ( ... for regional manufacturers at its Maple Grove, Minnesota technical center, May 11-12. ... and Trumpf. Almost 20 leading suppliers of tooling, accessories, software and other ...
(Date:4/27/2016)... ... April 27, 2016 , ... Most ... devices with fingerprint recognition for secure access, voice recognition for hands-free communication, and ... consumers are interacting with biometrics technology today. But if they asked Joey ...
(Date:4/27/2016)... ... April 27, 2016 , ... NDA Partners Chairman Carl ... an Expert Consultant. Mr. Clark was formerly a Vice President with US ... small molecule monographs based on analytical methods. NDA Partners Expert Consultants are ...
(Date:4/27/2016)... ... April 27, 2016 , ... Global Stem Cells Group and the ... as other research and development initiatives for potential stem cell protocol management for 2016 ... Cells Group executives began meeting to establish a working agenda and foster initiatives to ...
Breaking Biology Technology:
Cached News: