HOME >> BIOLOGY >> NEWS
Research teams uncover risk genes for multiple sclerosis

d Hafler, MD, the Jack, Sadie and David Breakstone professor of neurology at Harvard Medical School and Brigham and Womens Hospital, another of the consortium study authors. This study will likely spur further research into the connection between these seemingly separate conditions.

These advances are an outgrowth of a 15-year effort at UCSF to create a national repository of more than 10,000 samples of DNA from people with MS and their families, the largest such collection nationwide. A similar database, in both quantity and quality, had been developed at the University of Cambridge, in England. Both collections were used for both of these studies.

But the real breakthroughs came through collaboration. Hauser said that individually, none of the six centers in the consortium could have completed a study of this scale and complexity, but by using a Collaborative Research Award from the National MS Society, they were able to form a truly effective international consortium that could deliver the most exhaustive search for MS risk factors ever published.

The consortium paper is among a series of recent whole-genome association studies that have begun to uncover the genetic basis of complex diseases like diabetes, schizophrenia, and coronary artery disease. Unlike diseases caused by a mutation in a single gene, these conditions seem to arise from a combination of genetic, behavioral and environmental factors.

Jorge Oksenberg, PhD, a UCSF neurology professor who has been involved in the development of the UCSF collection for more than a decade, said that it wasnt until scientists were able to combine the potential of both repositories with the intellectual and financial resources of previously competing research teams that they were able to make the connections represented in these studies.

For studying these complex genetic diseases, where were looking at many genes contributing and each one contributing just a littl
'"/>

Contact: Kristen Bole
kbole@pubaff.ucsf.edu
415-476-2557
University of California - San Francisco
30-Jul-2007


Page: 1 2 3 4

Related biology news :

1. Gilbert Foundation and American Fed for Aging Research award grants on Alzheimers disease
2. Research shows skeleton to be endocrine organ
3. Research aims to identify markers for menopausal women at risk for deadly blood clot
4. Research team enlightens the reasons for severe blindness
5. Research shows NPD1 protects a key component of vision
6. Researchers find pathway that controls cell size and division
7. Researchers watch antibiotics, bacteria meet at atomic level
8. Researchers discover gene responsible for Restless Legs Syndrome
9. Research study describes the role part of the brain plays in memory
10. NY Stem Cell Foundations 2nd Annual Translational Stem Cell Research Conference
11. Researchers witness natural selection at work in dramatic comeback of male butterflies

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/6/2017)... 6, 2017 Forecasts by Product ... Readers, by End-Use (Transportation & Logistics, Government & Public ... & Fossil Generation Facility, Nuclear Power), Industrial, Retail, Business ... Are you looking for a definitive report on ... ...
(Date:4/3/2017)... 3, 2017  Data captured by IsoCode, ... detected a statistically significant association between the ... treatment and objective response of cancer patients ... predict whether cancer patients will respond to ... well as to improve both pre-infusion potency testing ...
(Date:3/28/2017)... PUNE, India , March 28, 2017 ... (Analog, IP, Biometrics), Hardware (Camera, Monitors, Servers, Storage Devices), ... Maintenance), Vertical, and Region - Global Forecast to 2022", ... 30.37 Billion in 2016 and is projected to reach ... 15.4% between 2017 and 2022. The base year considered ...
Breaking Biology News(10 mins):
(Date:4/25/2017)... CA (PRWEB) , ... April 25, 2017 , ... ... of L3 Healthcare, is pleased to announce the company is now a certified ... The iMedNet software certification enables the company’s clinical research team to build, ...
(Date:4/25/2017)... ... 25, 2017 , ... Leaders of Quorum Review IRB and ... sessions at this week’s Association of Clinical Research Professionals (ACRP) 2017 Meeting & ... research. , "We are excited to present subject matter expertise on topics that impact ...
(Date:4/21/2017)... ... 2017 , ... Having worked on the design of the innovative Triton™ ... to top lab design architects from around the country at the Lab Design Conference ... and Engineering Greg Casey will be at the show, where they will highlight the ...
(Date:4/21/2017)... ... April 21, 2017 , ... ... nourishing a range of emerging bio and technology start-ups, is hosting “Celebration Friday” ... This double event will start with libations and networking at 3:30 p.m. at ...
Breaking Biology Technology:
Cached News: