HOME >> BIOLOGY >> NEWS
Researchers aim to cut future need for liver transplants

University of Edinburgh scientists have identified primitive liver cells possibly dormant from the earliest developmental stage of a human being which have the potential to mature into different cells types and help repair a failing liver. Their newly-published findings could pave the way for alternative treatments using cell replacements instead of organ transplants for those with liver failure.

A functioning liver is essential for human survival with liver failure ultimately resulting in death, and liver transplantation is presently the only treatment for acute and chronic liver failure. However, the supply of donor livers is insufficient to meet demand, and in the United Kingdom, 20% of patients waiting for a liver transplant will die from liver failure before a suitable donated organ becomes available.

Head of the group Dr James Ross said: "Potentially, cell replacement therapies could provide alternative treatments that would avoid difficulties associated with obtaining sufficient donor organ transplantation. We have now identified primitive cells with the potential to mature into different cell types within and out with the liver. It is possible that these cells lie dormant in the adult liver and may be the source of repair cells that are activated by severe liver injury."

"The liver is often able to repair and heal itself following injury or damage and this occurs in one of three ways. Firstly, mature liver cells have a well recognised and extensive capacity to divide in response to injury. Secondly, in response to massive loss of functioning liver tissue, a population of primitive liver stem cells may be stimulated to proliferate and develop into mature liver cells. The third mechanism of liver repair involves circulating stem cells originating from other sources, such as the bone marrow, and it is possible that these cells may be recruited into the liver and form new liver cells."


'"/>

Contact: Linda Menzies
Linda.Menzies@ed.ac.uk
44-131-650-6382
University of Edinburgh
6-Jul-2006


Page: 1

Related biology news :

1. Researchers find pathway that controls cell size and division
2. Researchers watch antibiotics, bacteria meet at atomic level
3. Researchers discover gene responsible for Restless Legs Syndrome
4. Researchers witness natural selection at work in dramatic comeback of male butterflies
5. Researchers discover human embryonic stem cells are the ultimate perpetual fuel cell
6. Researchers use new approach to predict protein function
7. Researchers probe risks, benefits of folic acid fortification
8. Researchers identify genetic mutation that may alter tumor cell proliferation
9. Researchers discover method for identifying how cancer evades the immune system
10. Researchers use adult stem cells to create soft tissue
11. Researchers find gene that spurs development of the epididymis

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/25/2019)... ... June 25, 2019 , ... ... Using 23andMe raw data, easily available from 23andMe, customers can get access to ... service is available for both 23andMe Ancestry and Health + Ancestry customers., With ...
(Date:6/16/2019)... , ... June 14, 2019 , ... ... invited to lecture at the fifth annual Neodent World Congress. Attended by thousands ... innovative progress and latest advancements in the world of dentistry. The three-day event ...
(Date:6/11/2019)... ... June 12, 2019 , ... With a rapidly growing ... leverage the Geneious Biologics platform as a premium hub for bioinformatics and computer ... says: “The Geneious team has done an excellent job accommodating our specific data, ...
Breaking Biology News(10 mins):
(Date:6/12/2019)... EGG HARBOR TOWNSHIP, N.J. (PRWEB) , ... June ... ... premier manufacturer of custom built, helium-based leak testing instruments for the Pharmaceutical, Biotechnology, ... partnership agreement with Shanghai Zillion has been signed. The agreement will grant exclusive ...
(Date:6/11/2019)... CITY, Calif. (PRWEB) , ... June 10, 2019 ... ... (IOPP) today announced IOPP will add 80 of its scientific journals to DeepDyve’s ... of physics-related content to DeepDyve’s continually expanding library of more than 20 million ...
(Date:6/11/2019)... ... June 11, 2019 , ... A study released ... cells (MSC-EV) are able to incorporate into human CD34+ cells, modifying their gene ... MSC-EVs also increased the cells’ ability to lodge into bone marrow. This research ...
(Date:5/31/2019)... (PRWEB) , ... May 29, ... ... our patent applications from the USPTO providing proprietary interest to our methodology, ... FOR SLEEP DISORDER DIAGNOSIS AND TREATMENT… extends Somnology’s IP rights including our ...
Breaking Biology Technology:
Cached News: