HOME >> BIOLOGY >> NEWS
Researchers at IRB Barcelona discover a new mechanism that regulates stem cell division

Errors in stem cell division can give rise to tumours. By studying stem cells in the fruit fly, scientists at the Institute for Research in Biomedicine (IRB Barcelona) have identified one of the mechanisms that govern how these cells divide. The study appears this week in the scientific journal Developmental Cell.

Stem cells have the extraordinary capacity to divide producing two very distinct cells: one retains stem cell identity and continues to undergo asymmetric division, while the other specializes for a specific function and shows limited capacity to divide. This strategy allows a single stem cell to generate great amounts of tissue during a lifetime.

To ensure the correct differential identity of the resulting cells, the complex apparatus that divides that stem cell in two must form along a pre-established axis. If this does not occur, the division may be symmetric, which will generate two identical stem cells. That is to say, instead of producing tissue, the stem cells with a "disoriented" division axis may give rise to more stem cells; this is potentially dangerous for the organism as it would lead to uncontrolled proliferation of this type of cell.

How is this danger avoided? Researchers headed by Cayetano Gonzlez, ICREA Research Professor at IRB Barcelona, have studied stem cell division and discovered that one of the key factors lies in the behaviour of the intracellular structure known as the centrosome. Most animal cells have two centrosomes before division takes place and their position governs the direction of the division. In cells that divide symmetrically (giving rise to two identical cells), the two centrosomes of cell are practically identical. Surprisingly, Gonzalez and his team found striking differences in the two centrosomes of the stem cells they were studying. One is located in a fixed position and is very active during the entire cell cycle, while the other moves around the cell before coming to a stands
'"/>

Contact: Sonia Armengou
sarmengou@pcb.ub.es
34-934-037-255
Institute for Research in Biomedicine (IRB)
5-Mar-2007


Page: 1 2

Related biology news :

1. Researchers find pathway that controls cell size and division
2. Researchers watch antibiotics, bacteria meet at atomic level
3. Researchers discover gene responsible for Restless Legs Syndrome
4. Researchers witness natural selection at work in dramatic comeback of male butterflies
5. Researchers discover human embryonic stem cells are the ultimate perpetual fuel cell
6. Researchers use new approach to predict protein function
7. Researchers probe risks, benefits of folic acid fortification
8. Researchers identify genetic mutation that may alter tumor cell proliferation
9. Researchers discover method for identifying how cancer evades the immune system
10. Researchers use adult stem cells to create soft tissue
11. Researchers find gene that spurs development of the epididymis

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/30/2017)... The research team of The Hong Kong Polytechnic University (PolyU) ... ground breaking 3D fingerprint minutiae recovery and matching technology, pushing contactless ... use in identification, crime investigation, immigration control, security of access and ... ... A research team led by Dr Ajay Kumar ...
(Date:3/27/2017)... CENTRE, N.Y. , March 27, 2017 /PRNewswire-USNewswire/ ... Healthcare Information and Management Systems Society (HIMSS) Analytics ... Outpatient EMR Adoption Model sm . In addition, ... 12% of U.S. hospitals using an electronic medical ... CHS for its high level of EMR usage ...
(Date:3/23/2017)... Mar. 23, 2017 Research and Markets has ... Analysis & Trends - Industry Forecast to 2025" report to ... ... a CAGR of around 8.8% over the next decade to reach ... analyzes the market estimates and forecasts for all the given segments ...
Breaking Biology News(10 mins):
(Date:8/16/2017)... ... 16, 2017 , ... We are proud to announce the ... our Dilworth, MN site. The inspection took place Monday, July 31st through Friday, ... of a routine Bioresearch Monitoring Program (BIMO) with the USFDA wherein multiple Dermatology ...
(Date:8/15/2017)... (PRWEB) , ... August 15, 2017 , ... Kapstone ... celebrating 10 years of successes helping medical technology companies and inventors develop and safeguard ... a renowned full-service national engineering firm with a portfolio of clients in the United ...
(Date:8/15/2017)... , ... August 15, 2017 , ... ... family of 6” modular downlights designed to stay tightly sealed and perform efficiently ... where damp and wet location listings just aren't enough, such as: hospitals; behavioral ...
(Date:8/14/2017)... ... August 14, 2017 , ... Every year, ... researchers in the antibody community have recently come together to address this antibody ... the laboratory. , The team at Thermo Fisher Scientific ...
Breaking Biology Technology:
Cached News: