HOME >> BIOLOGY >> NEWS
Researchers debut new X-ray resources for studying molecules

nstead of which buttons to push," said Janet Smith, Ph.D., a structural biologist at the University of Michigan in Ann Arbor and director of the development team.

Taking advantage of new technology, the additional experimental stations at APS can accommodate many robotic and automated tools. This capability could enable researchers to conduct their studies from their home laboratories.

Smith credited the Protein Structure Initiative, a 10-year, $600 million program funded largely by NIGMS, for driving the development of automated systems that will enhance the performance of the new resources at the DOE facility.

The beamlines also are the first to utilize novel APS technology that splits a single X-ray beam into two and then manipulates each one so it's just as intense as the original.

"The ability to do two experiments simultaneously from the same light source is a big bonus," explained Smith. "It doubles the value of real estate at the synchrotron."

But where the new beamlines really show their power is in their ability to produce extremely fine X-ray beams. This feature enables researchers to capture data on molecules that have been challenging to work with in the past.

Already, the new facilities have produced exciting results. One research team has succeeded in generating a detailed structure of the bacteria-infecting HK97 virus--a notable achievement given that most viruses are complex and difficult to image at high resolutions. Knowing the structures of viruses and proteins and how they attach to other molecules will help researchers develop drugs that block those interactions.

"The properties of these X-ray beams are even better than we envisioned," said Charles Edmonds, Ph.D., NIGMS scientific director for the interagency project. "They will allow researchers to do new kinds of experiments, leading to even more ideas and questions to ask."

Structural biologists wi
'"/>

Contact: Emily Carlson
carlsone@nigms.nih.gov
301-496-7301
NIH/National Institute of General Medical Sciences
23-Jun-2005


Page: 1 2 3

Related biology news :

1. Researchers find pathway that controls cell size and division
2. Researchers watch antibiotics, bacteria meet at atomic level
3. Researchers discover gene responsible for Restless Legs Syndrome
4. Researchers witness natural selection at work in dramatic comeback of male butterflies
5. Researchers discover human embryonic stem cells are the ultimate perpetual fuel cell
6. Researchers use new approach to predict protein function
7. Researchers probe risks, benefits of folic acid fortification
8. Researchers identify genetic mutation that may alter tumor cell proliferation
9. Researchers discover method for identifying how cancer evades the immune system
10. Researchers use adult stem cells to create soft tissue
11. Researchers find gene that spurs development of the epididymis

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:1/27/2016)... , Jan. 27, 2016  Rite Track, Inc. a ... West Chester, Ohio announced today ... service staff, based in Austin, Texas ... ability to provide modifications, installations and technical support offerings ... CEO of PLUS, commented, "PLUS has provided world class ...
(Date:1/22/2016)... DUBLIN , January 22, 2016 ... has announced the addition of the  ... to their offering. --> ... of the  "Global Behavioral Biometric Market ... --> Research and Markets ( http://www.researchandmarkets.com/research/4lmf2s/global_behavioral ...
(Date:1/20/2016)... , Jan. 20, 2016 A market ... to directly benefit from the explosion in genomics knowledge. ... Howe Sound Research. A range of dynamic trends are ... - personalized medicine - pharmacogenomics - pathogen evolution ... with large markets - greater understanding of the role ...
Breaking Biology News(10 mins):
(Date:2/4/2016)... ... , ... Many of the engineers at FireflySci, Inc. have been manufacturing quartz ... from other cuvette manufacturers is their supercharged customer service and their extensive database of ... steady flow of inside information, they have recently revamped their manufacturing techniques to reduce ...
(Date:2/3/2016)... , Feb. 3, 2016 Ascendis Pharma ... company that applies its innovative TransCon technology to address ... at an upcoming investor conference.Event:2016 Leerink Partners Global Healthcare ... Date:  , Wednesday, February 10, 2016 Time:  , ... www.ascendispharma.com . --> An audio webcast of ...
(Date:2/3/2016)... ... February 03, 2016 , ... ... series of potential targets (epitopes) specific to misfolded, propagating strains of Amyloid beta ... specific monoclonal antibody therapeutics for Alzheimer’s. , Following on from the first misfolded ...
(Date:2/3/2016)... , Feb. 3, 2016  Today, Symphony Technology Group ... AlphaImpactRx , a leading provider of primary research and ... IMS Health , a global information and technology ... capabilities and technologies will be integrated into IMS Health ... primary market research capabilities. ...
Breaking Biology Technology:
Cached News: