HOME >> BIOLOGY >> NEWS
Researchers debut new X-ray resources for studying molecules

nstead of which buttons to push," said Janet Smith, Ph.D., a structural biologist at the University of Michigan in Ann Arbor and director of the development team.

Taking advantage of new technology, the additional experimental stations at APS can accommodate many robotic and automated tools. This capability could enable researchers to conduct their studies from their home laboratories.

Smith credited the Protein Structure Initiative, a 10-year, $600 million program funded largely by NIGMS, for driving the development of automated systems that will enhance the performance of the new resources at the DOE facility.

The beamlines also are the first to utilize novel APS technology that splits a single X-ray beam into two and then manipulates each one so it's just as intense as the original.

"The ability to do two experiments simultaneously from the same light source is a big bonus," explained Smith. "It doubles the value of real estate at the synchrotron."

But where the new beamlines really show their power is in their ability to produce extremely fine X-ray beams. This feature enables researchers to capture data on molecules that have been challenging to work with in the past.

Already, the new facilities have produced exciting results. One research team has succeeded in generating a detailed structure of the bacteria-infecting HK97 virus--a notable achievement given that most viruses are complex and difficult to image at high resolutions. Knowing the structures of viruses and proteins and how they attach to other molecules will help researchers develop drugs that block those interactions.

"The properties of these X-ray beams are even better than we envisioned," said Charles Edmonds, Ph.D., NIGMS scientific director for the interagency project. "They will allow researchers to do new kinds of experiments, leading to even more ideas and questions to ask."

Structural biologists wi
'"/>

Contact: Emily Carlson
carlsone@nigms.nih.gov
301-496-7301
NIH/National Institute of General Medical Sciences
23-Jun-2005


Page: 1 2 3

Related biology news :

1. Researchers find pathway that controls cell size and division
2. Researchers watch antibiotics, bacteria meet at atomic level
3. Researchers discover gene responsible for Restless Legs Syndrome
4. Researchers witness natural selection at work in dramatic comeback of male butterflies
5. Researchers discover human embryonic stem cells are the ultimate perpetual fuel cell
6. Researchers use new approach to predict protein function
7. Researchers probe risks, benefits of folic acid fortification
8. Researchers identify genetic mutation that may alter tumor cell proliferation
9. Researchers discover method for identifying how cancer evades the immune system
10. Researchers use adult stem cells to create soft tissue
11. Researchers find gene that spurs development of the epididymis

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Researchers debut new ray resources for studying molecules

(Date:11/4/2014)... the right time might actually help boost a species, ... in understanding animal populations, pest control and managing fish ... journal Trends in Ecology and Evolution , a ... kind of positive population effect an overall species experiences ... the size and developmental stage of the creatures that ...
(Date:11/4/2014)...   3D scanner ... Fuel3D , a developer of 3D scanning solutions, ... $6.4 million (£4 million). This funding builds on the company,s ... and paves the way for the commercial launch of the ... round was led by Chimera Partners and will be used ...
(Date:11/3/2014)... University of Colorado Cancer Center study published ... of Sciences describes the activity of a recently ... 37 or IL-37. It has been known to limit ... the adaptive immune system: IL-37 inhibits the ability of ... , "Knowing this mechanism that underlies IL-37,s effect on ...
Breaking Biology News(10 mins):When less is more: Death in moderation boosts population density in nature 2Fuel3D Secures $6.4 Million in Expansion Funding 2Fuel3D Secures $6.4 Million in Expansion Funding 3PNAS: From HIV to cancer, IL-37 regulates immune system 2
(Date:11/24/2014)... , Nov. 24, 2014  IGI Laboratories, Inc. ... based specialty generic pharmaceutical company, today announced it ... to the U.S. Food and Drug Administration (FDA), which ... 2014 to seven, with eighteen submissions now pending at ... President and CEO of the Company, commented, "Our team ...
(Date:11/24/2014)... , Nov. 24, 2014  Last week, Representatives ... Butterfield (D-NC) took a bold bipartisan step ... introducing the OPEN Act. Original co-sponsors of the ... The Act will incentivize drug makers and innovators ... diseases and pediatric cancers, which opens the door ...
(Date:11/24/2014)...   First published articles now available ... , a world-leading provider of scientific, technical and medical information ... the latest title in the Current Opinion journal series ... . Current Opinion in Food ... keep up-to-date with the expanding volume of information published in ...
(Date:11/24/2014)... November 23, 2014 One of the most ... optics and photonics is now available to high school and ... cost. SPIE, the international society for optics and photonics ... complete SPIE Digital Library available to high schools ... “Light-based technologies are integral to all areas of life in ...
Breaking Biology Technology:IGI Laboratories, Inc. Announces ANDA Submission 2OPEN Act Introduced to Repurpose Drugs for Rare Diseases 2Elsevier Announces Launch of New Journal: Current Opinion in Food Science 2Elsevier Announces Launch of New Journal: Current Opinion in Food Science 3SPIE Digital Library Now Available to High Schools, Two-Year Colleges at No or Low Cost 2
Cached News: