HOME >> BIOLOGY >> NEWS
Researchers devise way to mass-produce embryonic stem cells

That's important because traditional laboratory methods used to grow these cells are costly and don't produce cells fast enough to respond to increasing demands for human embryonic stem cells, said Shang-Tian Yang, a professor of chemical and biomolecular engineering at Ohio State University.

Federal rules forbid the federal funding of research on human embryonic stem cell lines that aren't listed on the National Institutes of Health's Human Embryonic Stem Cell Registry. There are currently 22 embryonic stem cell lines on the registry, and the demand for these cells is steadily growing.

"We have to find a way to mass-produce them because traditional cell culturing methods can't meet the projected high market demand for stem cells," Yang said.

He and Anli Ouyang, a doctoral student in chemical engineering, grew mouse embryonic stem cells in a bioreactor. Cell growth increased 193-fold in 15 days. At the end of that period, cell density the number of cells that had grown in the bioreactor was anywhere from 10- to 100-fold higher than the number of stem cells produced by conventional laboratory methods. That's several hundreds of millions more stem cells.

Mass-producing cells like this could reduce stem cell production costs by at least 80 percent, Yang said, as it requires less equipment and monitoring.

Embryonic stem cells are unspecialized, or undifferentiated, cells that can grow into any of the body's 200 different types of cells.

Yang and Ouyang presented their findings in San Diego on March 15 at the national meeting of the American Chemical Society.

They grew some mouse embryonic stem cells in a flask a conventional way to grow stem cells while other stem cells grew upon strands of polymer threads inside a bioreactor.

The bioreactor used in this study is a tissue-growing device developed by Ohio State scientists. While this bioreactor could be used to produce adult stem cells, the researchers c
'"/>

Contact: Shang-Tian Yang
Yang.15@osu.edu
614-292-6611
Ohio State University
15-Mar-2005


Page: 1 2 3

Related biology news :

1. Researchers find pathway that controls cell size and division
2. Researchers watch antibiotics, bacteria meet at atomic level
3. Researchers discover gene responsible for Restless Legs Syndrome
4. Researchers witness natural selection at work in dramatic comeback of male butterflies
5. Researchers discover human embryonic stem cells are the ultimate perpetual fuel cell
6. Researchers use new approach to predict protein function
7. Researchers probe risks, benefits of folic acid fortification
8. Researchers identify genetic mutation that may alter tumor cell proliferation
9. Researchers discover method for identifying how cancer evades the immune system
10. Researchers use adult stem cells to create soft tissue
11. Researchers find gene that spurs development of the epididymis

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:12/10/2018)... (PRWEB) , ... December 10, 2018 , ... ... a strategic alliance to advance their shared goal of accelerating the development of ... unique scale-up bioprocess systems to TRT’s core technology around human umbilical cord perivascular ...
(Date:12/5/2018)... ... December 03, 2018 , ... uBiome, the leader ... professor in the Division of Gastroenterology and Hepatology at UC San Diego and ... Board. Joining the board of leading scientists and doctors from around the world, ...
(Date:12/5/2018)... ... December 04, 2018 , ... ... the much-anticipated launch of their 100-liter (26 gallon) SAFEthread Drum. The 100-liter ... in 2017, which brought a much-needed modern redesign to the plastic drums being ...
Breaking Biology News(10 mins):
(Date:11/20/2018)... SPRINGS, Ga. (PRWEB) , ... November 19, 2018 , ... ... now receive custom dental implants from Dr. Dan Myers at THE DENTIST ... offering dental implant placement and restorations for the last 20 years. He now offers ...
(Date:11/20/2018)... , ... November 20, 2018 , ... Dr. Steven White ... for gingivitis at their office in Cornelius, NC. This common infection, left untreated, can ... in practice, along with special training and certification in laser dentistry, Drs. White and ...
(Date:11/13/2018)... ... November 13, 2018 , ... Renowned Honolulu veterinarian, Dr. Patrick Leadbeater, has ... Kauai. Dr. Leadbeater, of Kahala Pet Hospital on Oahu, is a ... began traveling to the island of Kauai on an almost weekly basis to perform ...
(Date:11/13/2018)... Sandy Springs, GA (PRWEB) , ... November 12, ... ... cosmetic dentist with state-of-the-art practices in Alpharetta and Sandy Springs, now welcomes ... clear aligners provide a discreet and comfortable alternative to traditional braces in the ...
Breaking Biology Technology:
Cached News: