HOME >> BIOLOGY >> NEWS
Researchers discover gene responsible for Restless Legs Syndrome

An international team of researchers has identified the first gene associated with Restless Legs Syndrome (RLS), a common sleep disorder affecting tens of millions of people worldwide. The findings will be published July 18 in the online edition of the New England Journal of Medicine and will appear in an upcoming printed edition of the journal. The work was led by scientists at Emory University and deCODE Genetics, Inc., in Reykjavik, Iceland.

Restless legs syndrome is a condition that produces an intense, often irresistible urge to move the legs and is a major cause of insomnia and sleep disruption. RLS affects approximately 10 percent of the U.S. population and about one percent of school-aged children. The discovery provides strong new evidence that RLS is a genuine syndrome, a fact which has recently been the subject of some debate.

"We now have concrete evidence that RLS is an authentic disorder with recognizable features and underlying biological basis," says David Rye, MD, PhD, professor of neurology at Emory University School of Medicine, director of the Emory Healthcare Program in Sleep, and one of the study's lead authors. "This is the most definitive link between genetics and RLS that has been reported to date. We have known for quite some time that the majority of RLS patients have a close family member with the disorder, and now we have found a gene which is clearly linked to RLS," says Dr. Rye.

The researchers report a population-attributable risk for RLS of at least 50 percent, meaning that were the gene variant not present, more than half of all RLS cases would disappear.

The variant is very common--nearly 65 percent of the population carries at least one copy of the variant. Two copies of the variant more than doubles one's risk of experiencing RLS.

According to Dr. Rye, having two copies does not ensure that one will develop symptoms of RLS. "There remain yet-to-be-identified medical, environmen
'"/>

Contact: Jennifer Johnson
jennifer.johnson@emory.edu
404-727-5696
Emory University
18-Jul-2007


Page: 1 2

Related biology news :

1. Researchers find pathway that controls cell size and division
2. Researchers watch antibiotics, bacteria meet at atomic level
3. Researchers witness natural selection at work in dramatic comeback of male butterflies
4. Researchers discover human embryonic stem cells are the ultimate perpetual fuel cell
5. Researchers use new approach to predict protein function
6. Researchers probe risks, benefits of folic acid fortification
7. Researchers identify genetic mutation that may alter tumor cell proliferation
8. Researchers discover method for identifying how cancer evades the immune system
9. Researchers use adult stem cells to create soft tissue
10. Researchers find gene that spurs development of the epididymis
11. Researchers isolate new risk marker for overweight children

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/7/2019)... ... 07, 2019 , ... Landsec and Spartan Bioscience today announced ... , In May, Landsec will undertake trials using Spartan’s innovative Legionella test. Spartan’s ... take corrective action within hours instead of weeks. This test, if approved, ...
(Date:5/2/2019)... ... 2019 , ... Philadelphia intellectual property law firm Panitch ... Ph.D., a registered patent agent, has joined the firm as a new member ... technical support and scientific expertise in the pharmaceutical and biotechnical arts and assists ...
(Date:5/2/2019)... ... May 01, 2019 , ... Gateway Genomics ... future children, announces a new publication titled, “ Self-Collection of Maternal Blood for ... Child Health. Previous studies had only shown early gender determination using venous blood. ...
Breaking Biology News(10 mins):
(Date:5/14/2019)... ... May 13, 2019 , ... Leak ... instruments for the Pharmaceutical, Biotechnology, Medical Device and Food Packaging Industries’ is excited ... website aims to improve LDA’s ability to communicate directly with the marketplace; serving ...
(Date:5/4/2019)... ... 03, 2019 , ... Diopsys Inc, the world leader in ... vision test, a new full field electroretinography (ffERG) protocol designed to detect ... Americans will have glaucoma, with black Americans having the highest prevalence rate. This ...
(Date:5/2/2019)... ... 02, 2019 , ... Boston Robotic Hair Restoration announces the ... the days of painful hair transplant procedures. Boston Robotic Hair Restoration offers the ... robotic intelligent solution to offer a minimally invasive procedure. With the ARTAS® iX ...
(Date:4/16/2019)... SAN ANTONIO (PRWEB) , ... April 16, 2019 ... ... biometrics-based human identification systems, applications, and technology, today announced that Bank South Pacific ... through a competitive RFP process. The bank awarded Fulcrum a contract to deliver ...
Breaking Biology Technology:
Cached News: