HOME >> BIOLOGY >> NEWS
Researchers discover gene responsible for Restless Legs Syndrome

An international team of researchers has identified the first gene associated with Restless Legs Syndrome (RLS), a common sleep disorder affecting tens of millions of people worldwide. The findings will be published July 18 in the online edition of the New England Journal of Medicine and will appear in an upcoming printed edition of the journal. The work was led by scientists at Emory University and deCODE Genetics, Inc., in Reykjavik, Iceland.

Restless legs syndrome is a condition that produces an intense, often irresistible urge to move the legs and is a major cause of insomnia and sleep disruption. RLS affects approximately 10 percent of the U.S. population and about one percent of school-aged children. The discovery provides strong new evidence that RLS is a genuine syndrome, a fact which has recently been the subject of some debate.

"We now have concrete evidence that RLS is an authentic disorder with recognizable features and underlying biological basis," says David Rye, MD, PhD, professor of neurology at Emory University School of Medicine, director of the Emory Healthcare Program in Sleep, and one of the study's lead authors. "This is the most definitive link between genetics and RLS that has been reported to date. We have known for quite some time that the majority of RLS patients have a close family member with the disorder, and now we have found a gene which is clearly linked to RLS," says Dr. Rye.

The researchers report a population-attributable risk for RLS of at least 50 percent, meaning that were the gene variant not present, more than half of all RLS cases would disappear.

The variant is very common--nearly 65 percent of the population carries at least one copy of the variant. Two copies of the variant more than doubles one's risk of experiencing RLS.

According to Dr. Rye, having two copies does not ensure that one will develop symptoms of RLS. "There remain yet-to-be-identified medical, environmen
'"/>

Contact: Jennifer Johnson
jennifer.johnson@emory.edu
404-727-5696
Emory University
18-Jul-2007


Page: 1 2

Related biology news :

1. Researchers find pathway that controls cell size and division
2. Researchers watch antibiotics, bacteria meet at atomic level
3. Researchers witness natural selection at work in dramatic comeback of male butterflies
4. Researchers discover human embryonic stem cells are the ultimate perpetual fuel cell
5. Researchers use new approach to predict protein function
6. Researchers probe risks, benefits of folic acid fortification
7. Researchers identify genetic mutation that may alter tumor cell proliferation
8. Researchers discover method for identifying how cancer evades the immune system
9. Researchers use adult stem cells to create soft tissue
10. Researchers find gene that spurs development of the epididymis
11. Researchers isolate new risk marker for overweight children

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:11/7/2018)... ... November 07, 2018 , ... John Powers, co-founder and President ... is pleased to announce that Gene Tox Lab Solutions, LLC has been admitted ... help healthcare organizations including hospitals and clinics manage their patient population through specialized ...
(Date:11/7/2018)... Mass. (PRWEB) , ... November 07, 2018 , ... ... special requests, and the flexibility to adjust to last-minute changes all contribute to ... Colpitts Clinical. The clinical trial patient travel and expense services provider says 80 ...
(Date:11/7/2018)... ... November 07, 2018 , ... ... solutions, announced today a modernized and streamlined White Label Program. This enhancement delivers ... newly established reseller administrative control portal. CallTower enhanced their white label program to ...
Breaking Biology News(10 mins):
(Date:11/5/2018)... ... November 05, 2018 , ... ... educational support for healthcare professionals through its website, http://www.glycomark.com , as part ... live chat and video option via the website in November from 9 a.m. ...
(Date:11/3/2018)... ... ... Triangle Insights Group, a premier life sciences consulting firm, announced today that ... the United States, appearing on this year’s Inc. 5000 list. Since its inception ... over the previous three years. , Separately, Triangle Insights was also ranked on ...
(Date:10/31/2018)... ... ... young Labrador retriever. Like most labs, Pippa is energetic, crazy, and fun-loving. When ... in her right knee. According to her mom, Kinsley, Pippa was limping constantly and ... heart to see Pippa lie around in pain because it hurt too much to play. ...
(Date:10/29/2018)... ... October 29, 2018 , ... PracticeMatch , a ... released its schedule of physician career fairs planned for 2019. The company has expanded ... hosting live events in the areas of the country which have the highest concentrations ...
Breaking Biology Technology:
Cached News: