HOME >> BIOLOGY >> NEWS
Researchers discover human embryonic stem cells are the ultimate perpetual fuel cell

Hamilton, ON. (July 11, 2007) A startling discovery on the development of human embryonic stem cells by scientists at McMaster University will change how future research in the area is done.

An article published in the prestigious scientific journal Nature this week reports on a new understanding of the growth of human stem cells. It had been thought previously that stem cells are directly influenced by cells in the local environment or niche, but the situation may be more complex. Human embryonic stem cells are perpetual machines that generate fuel for life.

In this weeks Nature, researchers of the McMaster Cancer and Stem Cell Research Institute show that human embryonic stem (ES) cells can actually produce distinctive niche cells, which then release stem-cell nourishing proteins to help keep their parents ticking over.

Scientific Director Mick Bhatia and colleagues provide the first evidence that human ES cells have the unique ability to generate human-ES-cell-derived fibroblast-like niche cells (hdFs) in vitro despite removal from their in vivo microenvironment. These hdFs then provide a continuous source of supportive proteins, including insulin-like growth factor 2 (IGF-II), which they now show could be the protein to sustain hESCs..

Researchers are interested in the relationship between stem cells and their niche, because the niche represents a route for modifying stem cell behaviour if human ES cells can be reliably guided down a particular pathway, then they can be more readily used for future clinical therapy to regenerate damaged tissue such as neurons for Parkinsons disease, or insulin producing cells for diabetes .

The research has been funded by the Canadian Institutes for Health Research and the National Cancer Institute of Canada.

The Nature article is the latest in a series of important papers published by scientists at the 18-month-old institute, which was established with funding
'"/>

Contact: Veronica McGuire
vmcguir@mcmaster.ca
905-525-9150 x22169
McMaster University
11-Jul-2007


Page: 1 2

Related biology news :

1. Researchers find pathway that controls cell size and division
2. Researchers watch antibiotics, bacteria meet at atomic level
3. Researchers discover gene responsible for Restless Legs Syndrome
4. Researchers witness natural selection at work in dramatic comeback of male butterflies
5. Researchers use new approach to predict protein function
6. Researchers probe risks, benefits of folic acid fortification
7. Researchers identify genetic mutation that may alter tumor cell proliferation
8. Researchers discover method for identifying how cancer evades the immune system
9. Researchers use adult stem cells to create soft tissue
10. Researchers find gene that spurs development of the epididymis
11. Researchers isolate new risk marker for overweight children

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/30/2017)... , March 30, 2017  On April 6-7, 2017, ... the Genome hackathon at Microsoft,s headquarters in ... competition will focus on developing health and wellness apps ... Hack the Genome is the first hackathon ... The world,s largest companies in the genomics, tech and ...
(Date:3/27/2017)... ROCKVILLE CENTRE, N.Y. , March 27, 2017 ... by Healthcare Information and Management Systems Society (HIMSS) ... Analytics Outpatient EMR Adoption Model sm . In ... top 12% of U.S. hospitals using an electronic ... recognized CHS for its high level of EMR ...
(Date:3/22/2017)... Lithuania , March 21, 2017   ... and object recognition technologies, today announced the release ... kit (SDK), which provides improved facial recognition using ... cameras on a single computer. The new version ... to improve accuracy, and it utilizes a Graphing ...
Breaking Biology News(10 mins):
(Date:5/16/2017)... ... May 16, 2017 , ... Genedata, a leading provider ... User Group Meetings, which will be held in Boston, Cambridge/UK, Shanghai, and ... in screening data analysis and learn about the latest advances in screening technologies ...
(Date:5/16/2017)... ... (PRWEB) May 16, 2017 , ... ... (CAOS), long-standing development partners Invibio Biomaterial Solutions, UK, and China’s Double Medical ... help expand knowledge of the implantation of Double Medical’s Direct Lateral Interbody ...
(Date:5/15/2017)... ... May 15, 2017 , ... ... the clinical skincare brand has today launched its first-ever cross-medium campaign, #StandFirm, with ... shared across digital and social media channels, emphasizing Algenist’s stance on individuality and ...
(Date:5/11/2017)... ... May 11, 2017 , ... Quorum Review IRB , the ... that it has joined SMART IRB , a platform designed to simplify the ... to ease burdens related to multi-site research and serve as a roadmap for institutions ...
Breaking Biology Technology:
Cached News: