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Researchers discover master metabolism regulator with profound effect on fat metabolism

ith the depletion of stored fats in the body.

These findings about the crucial regulatory role of GCN2 kinase in the metabolism have major implications for the treatment or prevention of obesity, which is associated with increased risk for heart disease, diabetes, hypertension, and osteoarthritis. "Most of all," Cavener says, "we hope to be able to devise dietary interventions that will significantly improve the health of millions of children all over the world who suffer from amino acid deprivation associated with protein malnutrition."


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Contact: Barbara K. Kennedy
science@psu.edu
814-863-4682
Penn State
6-Feb-2007


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