HOME >> BIOLOGY >> NEWS
Researchers discover transport molecule that allows boron into cells

DALLAS Nov. 4, 2004 Researchers at UT Southwestern Medical Center at Dallas have identified a protein that transports the essential nutrient boron into cells, where it is important for cell growth and bone development.

The findings are in the Nov. 5 edition of the journal Molecular Cell and are online.

The protein, NaBC1, is found in most tissues and is part of a large family of ion transporting proteins that allow charged molecules to travel across cell membranes. Ion transporters are embedded in the cell membrane, opening and closing like gates to let charged ions and molecules enter and leave the cell. The movement of these molecules affects numerous essential cellular functions.

Like other nutrients, cells must transport boron across the membrane to control its concentration within the cell. The discovery of NaBC1 may help scientists understand how cells control internal boron concentration and the role of boron in a wide range of cellular processes, such as cell growth and bone mineralization.

"NaBC1 is very specific for the transport of borate, which is found in nearly everything we eat," said Dr. Shmuel Muallem, professor of physiology and the study's senior author.

Borate, the form of boron that the body uses, is essential for plant growth, pollination and crop size but until recently, no one knew how it entered plant cells. A borate transporter discovered in the plant Arabidopsis by another research group was shown to be very similar to human NaBC1.

Dr. Muallem, who had been studying NaBC1 in another context, hypothesized that NaBC1 was the human borate transporter.

"Since animals, including humans, get enough boron from our diets, it's hard to study the effect of boron deficiency in animal models and humans, but under conditions of malnutrition, there may be a strong effect of boron deficiency on embryonic development and, in adults, on bone maintenance and metabolic function," said
'"/>

Contact: Amanda Siegfried
amanda.siegfried@utsouthwestern.edu
214-648-3404
UT Southwestern Medical Center
4-Nov-2004


Page: 1 2 3

Related biology news :

1. Researchers find pathway that controls cell size and division
2. Researchers watch antibiotics, bacteria meet at atomic level
3. Researchers discover gene responsible for Restless Legs Syndrome
4. Researchers witness natural selection at work in dramatic comeback of male butterflies
5. Researchers discover human embryonic stem cells are the ultimate perpetual fuel cell
6. Researchers use new approach to predict protein function
7. Researchers probe risks, benefits of folic acid fortification
8. Researchers identify genetic mutation that may alter tumor cell proliferation
9. Researchers discover method for identifying how cancer evades the immune system
10. Researchers use adult stem cells to create soft tissue
11. Researchers find gene that spurs development of the epididymis

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/5/2019)... ... 04, 2019 , ... PI’s new L-505 linear ... 0.005 microns resolution, respectively. The new design allows for very compact multi-axis assemblies, ... motors with linear encoders and low-friction ball-screws to simple open-loop stepper motors. ...
(Date:4/4/2019)... ... April 02, 2019 , ... The live session ... into the connectivity between product risk management (ISO 14971) and the clinical risk ... process. , With increasing global regulation and reimbursement challenges faced by medical device ...
(Date:4/1/2019)... ... April 01, 2019 , ... uBiome announces the ... Conditions” by the US Patent and Trademark Office on January 1, 2019 with ... uBiome collaborators Dr. Zachary Apte, Dr. Daniel Almonacid, Dr. Jessica Richman, and ...
Breaking Biology News(10 mins):
(Date:4/12/2019)... Fla. (PRWEB) , ... April 12, 2019 , ... ... explore recent developments in neurotechnology and will educate about innovative tools and devices ... Check your local listings for more information. , This segment of Advancements will ...
(Date:4/10/2019)... ... April 10, 2019 , ... After more than three months of renovation, Lajollacooks4u ... equipped with updated appliances and modern lighting and fixtures, and will provide additional workspace ... “We’ve seen tremendous growth in the demand for our team-building events and cooking classes ...
(Date:4/9/2019)... ... April 09, 2019 , ... Sonny Bar Lisa, or Sonny ... for approximately two months. After a series of diagnostics, an MRI was performed ... owner, Alison, researched the injury and found that VetStem Regenerative Cell Therapy ...
(Date:4/8/2019)... ... April 08, 2019 , ... CallTower, ... announced today the launch of their app integration solution, CT Cloud Unite. ... contact-orientated applications while using CT Cloud Voice and Skype for Business solutions. This ...
Breaking Biology Technology:
Cached News: