HOME >> BIOLOGY >> NEWS
Researchers discover transport molecule that allows boron into cells

DALLAS Nov. 4, 2004 Researchers at UT Southwestern Medical Center at Dallas have identified a protein that transports the essential nutrient boron into cells, where it is important for cell growth and bone development.

The findings are in the Nov. 5 edition of the journal Molecular Cell and are online.

The protein, NaBC1, is found in most tissues and is part of a large family of ion transporting proteins that allow charged molecules to travel across cell membranes. Ion transporters are embedded in the cell membrane, opening and closing like gates to let charged ions and molecules enter and leave the cell. The movement of these molecules affects numerous essential cellular functions.

Like other nutrients, cells must transport boron across the membrane to control its concentration within the cell. The discovery of NaBC1 may help scientists understand how cells control internal boron concentration and the role of boron in a wide range of cellular processes, such as cell growth and bone mineralization.

"NaBC1 is very specific for the transport of borate, which is found in nearly everything we eat," said Dr. Shmuel Muallem, professor of physiology and the study's senior author.

Borate, the form of boron that the body uses, is essential for plant growth, pollination and crop size but until recently, no one knew how it entered plant cells. A borate transporter discovered in the plant Arabidopsis by another research group was shown to be very similar to human NaBC1.

Dr. Muallem, who had been studying NaBC1 in another context, hypothesized that NaBC1 was the human borate transporter.

"Since animals, including humans, get enough boron from our diets, it's hard to study the effect of boron deficiency in animal models and humans, but under conditions of malnutrition, there may be a strong effect of boron deficiency on embryonic development and, in adults, on bone maintenance and metabolic function," said
'"/>

Contact: Amanda Siegfried
amanda.siegfried@utsouthwestern.edu
214-648-3404
UT Southwestern Medical Center
4-Nov-2004


Page: 1 2 3

Related biology news :

1. Researchers find pathway that controls cell size and division
2. Researchers watch antibiotics, bacteria meet at atomic level
3. Researchers discover gene responsible for Restless Legs Syndrome
4. Researchers witness natural selection at work in dramatic comeback of male butterflies
5. Researchers discover human embryonic stem cells are the ultimate perpetual fuel cell
6. Researchers use new approach to predict protein function
7. Researchers probe risks, benefits of folic acid fortification
8. Researchers identify genetic mutation that may alter tumor cell proliferation
9. Researchers discover method for identifying how cancer evades the immune system
10. Researchers use adult stem cells to create soft tissue
11. Researchers find gene that spurs development of the epididymis

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:12/18/2018)... POWAY, Calif. (PRWEB) , ... December 18, 2018 , ... ... Dressage. He has been competing for many years however in 2006, he had ... a trot. It was determined that he suffered from cartilage degeneration in his ...
(Date:12/13/2018)... ... December 13, 2018 , ... Study Protocol Summary of QC Procedure , 1 ... first assessment performed at the site., 3 - Three photos captured with Apple iPad ... in BOX., 5 - Photos moved to eAdjudication® and submitted to Reviewers., 6 - ...
(Date:12/13/2018)... , ... December 12, 2018 , ... ... advancement of regenerative cellular therapy, has announced the launch of Maxx-Cell, the world's ... a gold standard approach of aspirating a patients autologous bone marrow cells. Maxx™-Cell ...
Breaking Biology News(10 mins):
(Date:1/11/2019)... ... January 11, 2019 , ... Drawing on over 22 ... January 22, 2019 at 2:30pm EST will explore some of the key lessons that ... using one vendor vs. using multiple vendors, and find out how to ensure that ...
(Date:1/8/2019)... , ... January 08, 2019 , ... The American ... grant recipients were named by a selection committee made up of industry leaders identified ... The Career Development grants are mentored awards created to support ASGCT members designing transformative ...
(Date:1/4/2019)... ... January 03, 2019 , ... Calidi Biotherapeutics, ... cancer, today announced the founding of a scientific and medical advisory board (SMAB). ... key leaders in the Immuno-Oncology field. The founding members of Calidi Biotherapeutics SMAB ...
(Date:12/18/2018)... ... December 18, 2018 , ... USDM Life ... the life sciences industry, unveiled a completely redesigned website at http://www.usdm.com . ... browsing experience for their valued clients and business partners. , The website ...
Breaking Biology Technology:
Cached News: