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Researchers identify genetic mutation that may alter tumor cell proliferation

el that involves Lilly Research Laboratories in Indianapolis, TGen in Phoenix, Lilly Singapore Centre for Drug Discovery, and the Economic Development Board of Singapore, adds Richard Gaynor, MD, Vice President of Oncology Discovery at Eli Lilly & Company. He added, This mutation further validates AKT1 as an attractive drug target, and it also will be a valuable tool for the stratification of patients for targeted therapies. This paradigm of identifying specific defects in cancer cells to successfully develop innovative therapies has been validated with oncology drugs such as Gleevec in leukemia and Herceptin in breast cancer.


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Contact: Amy Erickson
aerickson@tgen.org
602-343-8522
The Translational Genomics Research Institute
4-Jul-2007


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