HOME >> BIOLOGY >> NEWS
Researchers probe risks, benefits of folic acid fortification

BOSTON Since the institution of nationwide folic acid fortification of enriched grains in the mid 1990s, the number of infants born in the United States and Canada with neural tube defects has declined by 20 percent to 50 percent. Concurrent with the institution of fortification, however, the rate at which new cases of colorectal cancer were diagnosed in men and women increased, report researchers at the Jean Mayer USDA Human Nutrition Research Center on Aging (USDA HNRCA) at Tufts University. Joel Mason, MD, director of the USDA HNRCAs Vitamins and Carcinogenesis Laboratory, and colleagues analyze the temporal association between folic acid fortification and the rise in colorectal cancer rates, and present their resulting hypothesis in an article in the July issue of Cancer Epidemiology Biomarkers & Prevention.

Nationwide fortification of enriched grains is generally considered one of the greatest advances in public health policy, says Mason, who is also an associate professor at the Friedman School of Nutrition Science and Policy at Tufts. But since the time that the food supply in North America was fortified with folic acid, we have been experiencing four to six additional cases of colorectal cancer for every 100,000 individuals each year compared to the trends that existed before fortification.

Our analysis suggests that this increase is not explained by chance or by increased cancer screening. Therefore, it is important to analyze risks and benefits of fortification, and encourage scientific debate in countries that are considering instituting or enhancing folic acid fortification.

Mason and colleagues analyzed data from national cancer registries, one in the United States and another in Canada. The US data were derived from the nationwide Surveillance Epidemiology and End Results (SEER) registry that publishes cancer occurrence rates and survival data, covering approximately 26 percent of the population. The Canadian data
'"/>

Contact: Siobhan Gallagher
siobhan.gallagher@tufts.edu
617-636-6586
Tufts University, Health Sciences
10-Jul-2007


Page: 1 2 3

Related biology news :

1. Researchers find pathway that controls cell size and division
2. Researchers watch antibiotics, bacteria meet at atomic level
3. Researchers discover gene responsible for Restless Legs Syndrome
4. Researchers witness natural selection at work in dramatic comeback of male butterflies
5. Researchers discover human embryonic stem cells are the ultimate perpetual fuel cell
6. Researchers use new approach to predict protein function
7. Researchers identify genetic mutation that may alter tumor cell proliferation
8. Researchers discover method for identifying how cancer evades the immune system
9. Researchers use adult stem cells to create soft tissue
10. Researchers find gene that spurs development of the epididymis
11. Researchers isolate new risk marker for overweight children

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/18/2018)... ... October 18, 2018 , ... Avastus Preclinical Services LLC, ... opening of its new West Cambridge flagship facility scheduled for December 1, 2018. ... lab, tissue culture, necropsy and surgery rooms will give the company a strong ...
(Date:10/18/2018)... COLLEGE STATION, Texas (PRWEB) , ... October 18, ... ... one step closer to reality , Texas A&M receives USDA-APHIS deregulation approval , ... ground into flour to deliver protein to millions of people, a project to ...
(Date:10/16/2018)... ... October 16, 2018 , ... ... of advanced software solutions for biopharmaceutical R&D, today announced Genedata Imagence®, the ... screening (HCS) images. The deep learning-based solution accelerates, by orders of magnitude, ...
Breaking Biology News(10 mins):
(Date:10/16/2018)... ... October 16, 2018 , ... Infinity Healing Center, along with ... revolutionary technology that effectively treats pain, reduces the need for opioids, and lowers ... technology using photobiomodulation (PBM) has been effective for the treatment of medical conditions ...
(Date:10/11/2018)... NY (PRWEB) , ... October 11, 2018 , ... ... in the treatment of diseases like leukemia, lymphoma, sickle cell anemia, among others, ... new therapies. Quick Specialized Healthcare Logistics’ new e-book provides expert advice on ways ...
(Date:10/5/2018)... ... October 04, 2018 , ... Earthres ... website that elevates the company’s brand identity and better reflects its current breadth ... broader range of engineering expertise and related support services to clients in seven ...
(Date:10/2/2018)... ... October 02, 2018 , ... ... this week that teams have initiated validation of standards and testing of procedures ... direction of Dr. Larry Kennedy, ACRES VP for Quality Management Systems and Chief ...
Breaking Biology Technology:
Cached News: