HOME >> BIOLOGY >> NEWS
Researchers solve mystery of how nuclear pores duplicate before cell division

La Jolla, CA Researchers have long wondered how nuclear pores the all-important channels that control the flow of information in and out of a cell's nucleus double in number to prepare for the split to come when a cell divides. Now, for the first time, scientists at the Salk Institute for Biological Studies watched as new funnel-like pore structures formed from scratch, and inserted themselves into the nuclear membrane.

This discovery adds to the picture of how a cell divides in such a way that the genome (genetic blueprint) encased inside the nucleus can continue communicating with the rest of the cell. "This issue is as important to understanding the cell cycle as is the question of how DNA replicates," says Martin Hetzer, Ph.D., an assistant professor in the Molecular and Cell Biology Laboratory and lead author of the study published in the xxx issue of the journal Science.

Nuclear pores are gigantic structures that control the transport of molecules such as RNA and protein in and out of a cell's inner sanctum, the nucleus, which safeguards the cell's genomic brain. All chemical reactions that occur in a cell emanate from the genes within the nucleus. "Maybe not surprisingly, any disturbance in the flow of information across the nuclear membrane can alter cell functioning," says Hetzer.

"Nuclear pores are truly amazing," says postdoctoral researcher and co-first author Maximiliano D'Angelo, Ph.D. "They are the biggest protein structures within a cell and control the entire traffic in and out of the cell's nucleus, from tiny molecules such as histones, which bind DNA, to huge structures such as ribosomes," he explained.

To form the transport channels that span the nuclear membrane, 30 different proteins, called nucleoporins, come together in an orderly fashion and insert themselves into the nuclear envelope, where they form eight-fold symmetrical nuclear pore complexes. Each protein is present in copies of eight or multiples o
'"/>

Contact: Gina Kirchweger
kirchweger@salk.edu
858-453-4100 x1340
Salk Institute
20-Apr-2006


Page: 1 2

Related biology news :

1. Researchers find pathway that controls cell size and division
2. Researchers watch antibiotics, bacteria meet at atomic level
3. Researchers discover gene responsible for Restless Legs Syndrome
4. Researchers witness natural selection at work in dramatic comeback of male butterflies
5. Researchers discover human embryonic stem cells are the ultimate perpetual fuel cell
6. Researchers use new approach to predict protein function
7. Researchers probe risks, benefits of folic acid fortification
8. Researchers identify genetic mutation that may alter tumor cell proliferation
9. Researchers discover method for identifying how cancer evades the immune system
10. Researchers use adult stem cells to create soft tissue
11. Researchers find gene that spurs development of the epididymis

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/24/2017)... , April 24, 2017 ... and partner with  Identity Strategy Partners, LLP (IdSP) ... "With or without President Trump,s March 6, 2017 ... Terrorist Entry , refugee vetting can be instilled with ... resettlement. (Right now, all refugee applications are suspended ...
(Date:4/13/2017)... , April 13, 2017 UBM,s Advanced ... will feature emerging and evolving technology through ... Innovation Summits will run alongside the expo portion of ... sessions, panels and demonstrations focused on trending topics within ... advanced design and manufacturing event will take place June ...
(Date:4/11/2017)... April 11, 2017 No two people ... at the New York University Tandon School of ... have found that partial similarities between prints are ... in mobile phones and other electronic devices can ... The vulnerability lies in the fact that fingerprint-based ...
Breaking Biology News(10 mins):
(Date:5/23/2017)... ... May 23, 2017 , ... Firmex ... solution that makes it easy for organizations to send and gather large files ... FTP software or email file size limitations. , Using the same market-tested ...
(Date:5/23/2017)... ... May 22, 2017 , ... A new Technology Hot ... California, this August will feature high-level speakers on quantum devices, graphene electronic tattoo ... and Photonics, the largest multidisciplinary optical sciences meeting in North America, will run ...
(Date:5/23/2017)... ... ... Cambridge Semantics , the leading provider of Big Data management and ... Expo in Boston May 23-25 with a featured speaker and solution demos of ... is also a finalist for the Best of Show award. , James LaPointe, Managing ...
(Date:5/21/2017)... LOS ANGELES, CA (PRWEB) , ... May 19, ... ... at the annual meeting and educational conference of the American Association of Bioanalysts ... at the Galleria Hotel in Houston. The conference reinforces AAB’s commitment to excellence ...
Breaking Biology Technology:
Cached News: