HOME >> BIOLOGY >> NEWS
Researchers uncover sequence of major rice pathogen

In a genomics milestone, an international consortium of researchers has for the first time lifted the veil from a fungal plant pathogen by sequencing the genome or set of all genes of the most destructive enemy of rice: Magnaporthe grisea, the fungus that causes rice blast disease.

Dr. Ralph Dean, professor of plant pathology and director of North Carolina State University's Center for Integrated Fungal Research, is the lead author of a research paper that describes the M. grisea genome, published in the April 21 issue of the journal Nature.

It is estimated that rice blast, the leading cause of rice loss, is responsible each year for killing enough rice to feed 60 million people worldwide.

In the Nature paper, Dean and his co-authors shed some light on the adaptations required by a fungus to cause disease. The researchers identify novel receptors that allow the fungus to recognize its environment; secreted proteins that are likely used as offensive weapons to damage rice plants; and redundant, or duplicate, mechanisms that protect the fungus from efforts to fight against it.

"It's a clever system," Dean says. "If you have important genes, you tend to have a lot of them."

The paper also reports that the M. grisea genome contains retro-elements, or remnants of viruses, living in what Dean calls "hot spots" in the genome.

"These virus remnants live in discreet parts of the genome and have high rates of recombination, which may be why the fungus can evolve new strains so quickly," Dean says.

M. grisea undoubtedly produces toxins which may enable it to be a more effective pathogen. However our knowledge is limited to date, Dean says. The genome sequence should give researchers "a better idea of what types of genes are involved in making the toxin molecules," he says.

Some of these genes reside in clusters, Dean says, so one focus will be to take apart the clusters and learn more about toxins and their p
'"/>

Contact: Dr. Ralph Dean
ralph_dean@ncsu.edu
919-513-0020
North Carolina State University
21-Apr-2005


Page: 1 2

Related biology news :

1. Researchers find pathway that controls cell size and division
2. Researchers watch antibiotics, bacteria meet at atomic level
3. Researchers discover gene responsible for Restless Legs Syndrome
4. Researchers witness natural selection at work in dramatic comeback of male butterflies
5. Researchers discover human embryonic stem cells are the ultimate perpetual fuel cell
6. Researchers use new approach to predict protein function
7. Researchers probe risks, benefits of folic acid fortification
8. Researchers identify genetic mutation that may alter tumor cell proliferation
9. Researchers discover method for identifying how cancer evades the immune system
10. Researchers use adult stem cells to create soft tissue
11. Researchers find gene that spurs development of the epididymis

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/21/2019)... CONSHOHOCKEN, Pa. (PRWEB) , ... May 21, 2019 , ... ... trial randomization and drug supply chain management, has been named one of Inc. Magazine’s ... , The full list , now featured on Inc.com and hitting the newsstands ...
(Date:5/21/2019)... ... May 21, 2019 , ... At their May 16 ... Tissue Engineered Medical Products (TEMPs) of the American Society for Testing and Materials ... Gaining this approval was the next step in the company’s plan to establish ...
(Date:5/14/2019)... (PRWEB) , ... May 13, 2019 , ... ... Tuesday, June 4th, at a very special Pre-EWMA 2019 event at Gothenburg’s Universeum ... the latest Trends, Opportunities and Innovations in Advanced Wound Care. , SmartTRAK’s Advanced ...
Breaking Biology News(10 mins):
(Date:4/16/2019)... ... April 16, 2019 , ... ... their project partner, the U.S. Army Center for Environmental Health Research (USACEHR), with ... Combined In-Licensing/Out-Licensing.” , Blue Sources, a veteran-owned company located at the Frederick Innovative ...
(Date:4/15/2019)... ... 15, 2019 , ... Sirrus, Inc., a developer of novel ... expansion to increase production of methylene malonate monomers and oligomers. , The expanded ... full-scale production facility, which is scheduled to break ground in 2019. “The expanded ...
(Date:4/10/2019)... ... April 10, 2019 , ... ... have locked into multiple agreements to help companies advance their innovations to ... industry, ranging from synthetic biology companies that are gene editing therapeutic cells ...
(Date:4/9/2019)... , ... April 09, 2019 , ... ... focused on increasing the capacity of life sciences organizations to accelerate innovation and ... Assurance platform in the past 12 months. , USDM’s Cloud Assurance ...
Breaking Biology Technology:
Cached News: