HOME >> BIOLOGY >> NEWS
Researchers use adult stem cells to create soft tissue

NEW YORK, June 28, 2007 Researchers from Columbia University Medical Center received a $2.5 million grant from the National Institute of Biomedical Imaging and Bioengineering to use stem cells to engineer soft tissue, developing a process that should ultimately allow scientists to use a patients own stem cells to develop tissue for facial reconstruction following disfiguring injuries from war, cancer surgery or accidents.

The Columbia research team, led by Jeremy Mao, D.D.S., Ph.D., associate professor of dental medicine, aims to create long-lasting soft tissue implants from mesenchymal stem cells harvested from the patients own bone marrow or adipose tissue. Mesenchymal stem cells can differentiate into bone, fat, cartilage and other types of cells.

Our research has shown that mesenchymal stem cells can create tissue that is biocompatible with the host and that the continuous generation of these cells can replenished the implant to reduce shrinkage, said Dr. Mao.

Currently, surgeons often graft from the patients own tissue, which creates additional wounds. Grafted cells also fail to stay alive, causing implants to shrink up to 70 percent and lose their shape and volume. Attempts have also been made to use fat cells left over after liposuction, but those cells also have a limited lifespan.

The Columbia team of biologists, biomedical engineers, biomaterial scientists, imaging experts and surgeons has shown that human mesenchymal stem cells can create long-lasting implants in mice. The implant is created by placing the stem cells into an FDA-approved scaffold that mimics the conditions needed to turn stem cells into fat cells. Because stem cells have the ability to replicate and differentiate, they can regenerate the soft tissue, keeping the implant from shrinking. In mice, these cells have successfully created fat cells that could be implanted and retained their size and shape for at least a month.

Because the imp
'"/>

Contact: Craig LeMoult
cel2113@columbia.edu
212-305-0820
Columbia University Medical Center
28-Jun-2007


Page: 1 2

Related biology news :

1. Researchers find pathway that controls cell size and division
2. Researchers watch antibiotics, bacteria meet at atomic level
3. Researchers discover gene responsible for Restless Legs Syndrome
4. Researchers witness natural selection at work in dramatic comeback of male butterflies
5. Researchers discover human embryonic stem cells are the ultimate perpetual fuel cell
6. Researchers use new approach to predict protein function
7. Researchers probe risks, benefits of folic acid fortification
8. Researchers identify genetic mutation that may alter tumor cell proliferation
9. Researchers discover method for identifying how cancer evades the immune system
10. Researchers find gene that spurs development of the epididymis
11. Researchers isolate new risk marker for overweight children

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/10/2019)... ... October 10, 2019 , ... Mindray, a global developer ... the American Society of Anesthesiologists 2019 Annual Meeting to visit exhibit #841 and ... Orlando, Florida, and will provide more than 14,000 healthcare professionals from around the ...
(Date:10/8/2019)... , ... October 07, 2019 , ... The future of ... the genetic level, resulting in people living longer, healthier lives. But it will be ... earth. , Leroy E. Hood, MD, PhD, Chief Strategy Officer and Co-Founder of the ...
(Date:10/3/2019)... ... 2019 , ... Personalized Stem Cells, Inc (“PSC”), a human adipose-derived ... clinical trial for stem cell treatment of knee osteoarthritis . The successful enrollment comes ... subsidiary of VetStem Biopharma. , PSC CEO, Michael Dale, stated, “We are proud that ...
Breaking Biology News(10 mins):
(Date:9/17/2019)... ... September 17, 2019 , ... Tucker, a Labrador retriever, was just a puppy ... was limping and lame on his right hip and elbow. At one year of ... “the worst case the vet had seen.” He was prescribed pain medications, both oral ...
(Date:9/17/2019)... ... September 16, 2019 , ... When a lot of researchers think ... for the complete 3D characterization of tissues through the use of confocal and light ... image analysis and advanced cell culture focused contract research organization and today offers ...
(Date:9/11/2019)... ... September 09, 2019 , ... Tunnell Consulting, an ... announced that its president and CEO Maryann Gallivan has been accepted into the ... Forbes Council accepted Gallivan based on the role she and Tunnell Consulting ...
(Date:9/11/2019)... (PRWEB) , ... September 10, 2019 , ... ... and manufacturing solutions for drugs, biologics, gene therapies, and consumer health products, today ... to be held at the Bausparkasse Schwäbisch Hall AG, Schwabisch Hall, Germany, on ...
Breaking Biology Technology:
Cached News: