HOME >> BIOLOGY >> NEWS
Researchers use adult stem cells to create soft tissue

NEW YORK, June 28, 2007 Researchers from Columbia University Medical Center received a $2.5 million grant from the National Institute of Biomedical Imaging and Bioengineering to use stem cells to engineer soft tissue, developing a process that should ultimately allow scientists to use a patients own stem cells to develop tissue for facial reconstruction following disfiguring injuries from war, cancer surgery or accidents.

The Columbia research team, led by Jeremy Mao, D.D.S., Ph.D., associate professor of dental medicine, aims to create long-lasting soft tissue implants from mesenchymal stem cells harvested from the patients own bone marrow or adipose tissue. Mesenchymal stem cells can differentiate into bone, fat, cartilage and other types of cells.

Our research has shown that mesenchymal stem cells can create tissue that is biocompatible with the host and that the continuous generation of these cells can replenished the implant to reduce shrinkage, said Dr. Mao.

Currently, surgeons often graft from the patients own tissue, which creates additional wounds. Grafted cells also fail to stay alive, causing implants to shrink up to 70 percent and lose their shape and volume. Attempts have also been made to use fat cells left over after liposuction, but those cells also have a limited lifespan.

The Columbia team of biologists, biomedical engineers, biomaterial scientists, imaging experts and surgeons has shown that human mesenchymal stem cells can create long-lasting implants in mice. The implant is created by placing the stem cells into an FDA-approved scaffold that mimics the conditions needed to turn stem cells into fat cells. Because stem cells have the ability to replicate and differentiate, they can regenerate the soft tissue, keeping the implant from shrinking. In mice, these cells have successfully created fat cells that could be implanted and retained their size and shape for at least a month.

Because the imp
'"/>

Contact: Craig LeMoult
cel2113@columbia.edu
212-305-0820
Columbia University Medical Center
28-Jun-2007


Page: 1 2

Related biology news :

1. Researchers find pathway that controls cell size and division
2. Researchers watch antibiotics, bacteria meet at atomic level
3. Researchers discover gene responsible for Restless Legs Syndrome
4. Researchers witness natural selection at work in dramatic comeback of male butterflies
5. Researchers discover human embryonic stem cells are the ultimate perpetual fuel cell
6. Researchers use new approach to predict protein function
7. Researchers probe risks, benefits of folic acid fortification
8. Researchers identify genetic mutation that may alter tumor cell proliferation
9. Researchers discover method for identifying how cancer evades the immune system
10. Researchers find gene that spurs development of the epididymis
11. Researchers isolate new risk marker for overweight children

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:1/23/2020)... ... January 23, 2020 , ... Asymmetrex ... Regenerative Manufacturing Institute (ARMI). Headquartered in Manchester, New Hampshire, ARMI is the ... partner organizations from industry, government, academia and the non-profit sector to develop ...
(Date:1/10/2020)... ... January 09, 2020 , ... Cutting Edge Spine, a ... 510(K) clearance and commercial launch of the latest addition to its bioactive portfolio ... EVOL®ha-DLIF is made of PEEK-OPTIMA HA Enhanced material supplied by Invibio Biomaterial Solutions. ...
(Date:1/2/2020)... Texas (PRWEB) , ... January 02, 2020 , ... ... custom and semi-custom aqueous reagents, chemicals, and medias, as well as medical grade ... and cell- and tissue-based product manufacturers. , “We are excited to bring ...
Breaking Biology News(10 mins):
(Date:12/31/2019)... ... December 31, 2019 , ... ... product development lab in Maryland. Emphasis will be in expanding capabilities ... capabilities, Vici Health Sciences will be well positioned to meet the growing demand ...
(Date:12/27/2019)... ... December 27, 2019 , ... Leak Detection ... for the Pharmaceutical, Biotechnology, Medical Device and Food Packaging Industries is excited to ... Following acquisition by CLJ Holdings in February, 2019, a comprehensive and aggressive reorganization ...
(Date:12/18/2019)... Ariz. (PRWEB) , ... December 17, 2019 , ... ... has received its 31st FDA clearance for reprocessing Electrophysiology (EP) devices since the ... closest competitors, Stryker Sustainability Solutions and SterilMed (a Johnson & Johnson company) have ...
(Date:12/14/2019)... ... December 12, 2019 , ... ... built, helium-based leak testing instruments for the Pharmaceutical, Biotechnology, Medical Device and Food ... The new LDA LT80 (LOW TEMPERATURE -80C) helium leak testing system is designed ...
Breaking Biology Technology:
Cached News: