Revealed -- Mosquito genes that could be controlling the spread of killer viruses

The genes that make up the immune system of the Aedes aegypti mosquito which transmits deadly viral diseases to humans have been identified in new research out today in Science.

The immune system of this mosquito is of great importance as scientists believe it plays a key role in controlling the transmission of viruses that cause yellow and dengue fevers diseases that infect over 50 million people worldwide every year.

This study is the first of its kind on the newly-sequenced genome of the Aedes aegypti mosquito, which is also published in this weeks Science. The researchers identified over 350 genes which are involved in the Aedes mosquitos immune system, and discovered that they evolve much faster than the rest of the genes in the genome. Identifying which of these key genes are implicated in the transmission of viral diseases is an area of future research that could lead to new ways of combating these diseases. One possibility would be to affect the activity of the genes and therefore help the mosquitoes fight off the viruses more effectively, preventing transmission to humans.

Imperial College scientists participating in this study established previously that other mosquitoes do have a robust immune system that can either allow or block transmission of malaria parasites. Further research will be needed to ascertain whether some of the newly discovered genes in Aedes may provide a similar defence mechanism that can fight the disease viruses.

Dr George Christophides of Imperials Division of Cell and Molecular Biology, senior author on the paper explains: Our study has revealed the genetic landscape made by parts of this mosquitos newly-sequenced genome which are involved with immunity. By working to understand as much as possible about these genes, and the way they interact with specific pathogens, we hope to gain a more complete understanding of the mechanisms by which a pathogen either survives inside the insect b

Contact: Danielle Reeves
Imperial College London

Page: 1 2

Related biology news :

1. Mosquito genes explain response to climate change
2. Mosquito spray increases toxicity of pyrethroids in creek, study finds
3. Mosquito immune system examined
4. Mosquitoes are more attracted to individuals infected with malaria
5. Mosquito study shows new, faster way West Nile can spread
6. Health concerns: Mosquito mapping may help
7. Interaction of just 2 genes governs coloration patterns in mice
8. Gene regulation, not just genes, is what sets humans apart
9. Study finds gender differences in renal and other genes contributing to blood pressure
10. New databases put wings on search for bipolar risk genes
11. Research teams uncover risk genes for multiple sclerosis

Post Your Comments:

(Date:11/12/2015)... , Nov. 11, 2015   Growing need ... analytical tools has been paving the way for ... determination of discrete analytes in clinical, agricultural, environmental, ... being predominantly used in medical applications, however, their ... sectors due to continuous emphasis on improving product ...
(Date:11/9/2015)... 09, 2015 ... the "Global Law Enforcement Biometrics Market ... --> http://www.researchandmarkets.com/research/52ggmn/global_law ) has announced the ... Biometrics Market 2015-2019" report to their ... ( http://www.researchandmarkets.com/research/52ggmn/global_law ) has announced the addition ...
(Date:10/29/2015)... MINNETONKA, Minn. , Oct. 29, 2015   ... that supports the entire spectrum of clinical research, is ... the Minnesota High Tech Association (MHTA) as one of ... in the "Software – Small and Growing" category. The ... and individuals who have shown superior technology innovation and ...
Breaking Biology News(10 mins):
(Date:11/30/2015)... November 30, 2015 TapImmune, Inc. ... development of innovative peptide and gene-based immunotherapeutics and vaccines ... announced it will be presenting at the 8 th ... 2015 at 2.30 PM PT. Dr. John N. ... will be giving the presentation and will join TapImmune ...
(Date:11/30/2015)... BETHESDA, Md. , Nov. 30, 2015  Northwest ... biotechnology company developing DCVax® personalized immune therapies for solid ... to adding an additional independent director, and the Company ... investigation of allegations in a recent anonymous internet report ... on both initiatives. Linda Powers stated, ...
(Date:11/27/2015)... PA (PRWEB) , ... November 27, 2015 , ... ... Technical Program that includes over 2,000 technical presentations offered in symposia, oral ... chemistry and applied spectroscopy, covers a wide range of applications such as, but ...
(Date:11/25/2015)... , Nov. 25, 2015  PharmAthene, Inc. (NYSE ... has adopted a stockholder rights plan (Rights Plan) in ... operating loss carryforwards (NOLs) under Section 382 of the ... --> PharmAthene,s use of its NOLs could ... change" as defined in Section 382 of the Code. ...
Breaking Biology Technology:
Cached News: