HOME >> BIOLOGY >> NEWS
Rewiring the mammalian brain -- neurons make fickle friends

A new discovery from the Brain Mind Institute of the EPFL (Ecole Polytechnique Fdrale de Lausanne) shows that the brain rewires itself following an experience. The research further shows that this process of creation, testing, and reconfiguring of brain circuits takes place on a scale of just hours, suggesting that the brain is evolving considerably even during the course of a single day.

Scientists know that the strength of the connections between neurons changes to shape memories. They also know that the developing brain has a high level of plasticity as neurons forge connections with other neurons. This new research, published in the August 7, 2006 early online edition of the Proceedings of the National Academy of Sciences, goes further, investigating how neurons choose their connections with neighboring neurons. Researchers Henry Markram and Jean-Vincent Le B found that connections between neurons switch rapidly on and off, leading to a form of adaptive rewiring in which the brain is engaged in a continuous process of changing, strengthening and pruning its circuitry.

Studying neuron clusters from the neocortex of neonatal rats, Markram and Le B found that instead of growing preferentially towards specific receivers, neurons actually have no particular affinity for any other neuron, but instead remain in a state of perpetual readiness to reconfigure circuits. They found that over the course of just a few hours, connections are formed and re-formed many times.

"The circuitry of the brain is like a social network where neurons are like people, directly linked to only a few other people," explains Markram. "This finding indicates that the brain is constantly switching alliances and linking with new circles of "friends" to better process information."

In their samples, the rewiring process was occurring continuously at a slow pace. By exciting the sample with glutamate, they found that the rate increased markedly. This
'"/>

Contact: Mary Parlange
mary.parlange@epfl.ch
41-216-937-022
Ecole Polytechnique Fdrale de Lausanne
7-Aug-2006


Page: 1 2

Related biology news :

1. In a first, Einstein scientists discover the dynamics of transcription in living mammalian cells
2. St. Jude study solves mystery of mammalian ears
3. Doing nature one better: Expanding the genetic code in living mammalian cells
4. No need to thank dinosaur-killing asteroid for mammalian success
5. Chimpanzees found to use tools to hunt mammalian prey
6. Rong Li Lab demonstrates the process of mammalian egg maturation
7. Filling a niche -- role of Rb in mammalian stem cells
8. Non-coding RNAs help silence the mammalian transcription
9. Sexual reproduction delays aging in a mammalian species
10. Marsupial genome reveals insights into mammalian evolution
11. Fat overload kills mammalian cells key culprit identified

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/5/2017)... -- The Allen Institute for Cell Science today announces the ... and dynamic digital window into the human cell. The ... of deep learning to create predictive models of cell ... growing suite of powerful tools. The Allen Cell Explorer ... available resources created and shared by the Allen Institute ...
(Date:3/30/2017)... , March 30, 2017  On April 6-7, ... Hack the Genome hackathon at Microsoft,s headquarters ... two-day competition will focus on developing health and wellness ... Hack the Genome is the first ... tremendous. The world,s largest companies in the genomics, tech ...
(Date:3/27/2017)... N.Y. , March 27, 2017  Catholic ... Information and Management Systems Society (HIMSS) Analytics for ... EMR Adoption Model sm . In addition, CHS ... of U.S. hospitals using an electronic medical record ... for its high level of EMR usage in ...
Breaking Biology News(10 mins):
(Date:10/10/2017)... ... October 10, 2017 , ... ... company advancing targeted antibody-drug conjugate (ADC) therapeutics, today confirmed licensing rights that ... Polymerized Liposomal Nanoparticle), a technology developed in collaboration with Children’s Hospital Los ...
(Date:10/10/2017)... 2017 International research firm Parks Associates announced today ... the TMA 2017 Annual Meeting , October 11 in ... home security market and how smart safety and security products impact the ... Parks Associates: Smart Home Devices: ... "The residential security market has experienced ...
(Date:10/10/2017)... ... October 10, 2017 , ... The ... prestigious awards honoring scientists who have made outstanding contributions to analytical ... during Pittcon 2018, the world’s leading conference and exposition for laboratory science, which ...
(Date:10/9/2017)... ... October 09, 2017 , ... At its national board meeting in North Carolina, ... Harvard University’s Departments of Physics and Astronomy, has been selected for membership in ... team for the 2015 Breakthrough Prize in Fundamental physics for the discovery of the ...
Breaking Biology Technology:
Cached News: