Rotavirus can spread beyond the intestine

A new study in PLoS Medicine has shown that children who have rotavirus, a very common cause of diarrhea in children, and who have antigens (protein fragments from the surface of the virus) in their blood, also have infectious virus in their blood. Margaret Conner and colleagues from Baylor College of Medicine, Houston Texas, tested samples obtained from hospitalized children with gastroenteritis and compared them with samples taken from children admitted with bronchiolitis or noninfectious, nonchronic conditions and healthy adults.

Rotavirus antigen was detected in the blood of 51 of 57 of children with rotavirus-positive stools, in 8 of 9 of children without diarrhea but with rotavirus-positive stools, in 2 of 17 children with bronchiolitis of unknown cause without gastroenteritis, and in 5 of 41 children with gastroenteritis but with rotavirus-negative stools. No antigen was found in the blood of any other groups. A further study of 11 children who had antigen in their blood and 9 who did not showed that infectious virus was detected in the blood of all 11 children who were antigen-positive children but in just 2 out of 9 children who were antigen-negative.

The authors conclude that in the children studied most of those infected with rotavirus also had infectious virus in their blood. The presence of virus in the blood appears to be directly related to the presence of antigen in the blood but is independent of the presence of diarrhea. The finding of infectious rotavirus in the blood suggests that the disease is not limited to just the intestine. A related perspective by David Candy discusses the study’s findings further.


Contact: Andrew Hyde
Public Library of Science

Page: 1

Related biology news :

1. Proteaceae spread by continental drift and transoceanic dispersal
2. Californians urged to help reduce spread of Sudden Oak Death
3. Citrus greening continues to spread in citrus growing areas
4. A compound from olive-pomace oil gets 80 percent slowing down of HIV spread
5. Revealed -- Mosquito genes that could be controlling the spread of killer viruses
6. How memory T cells curb the spread of viruses throughout the body
7. Small-scale agricultural changes may help eradicate widespread disease
8. Cornell lab confirms deadly fish virus spreading to new species
9. Landmark study details demographic, ecological and genetic spread of rabies in raccoon outbreak
10. Cancer cells reprogram energy needs to grow and spread, study suggests
11. Supermap of avian flu yields new info on source/spread

Post Your Comments:

(Date:10/27/2015)... , Oct. 27, 2015 In the ... issues of concern for various industry verticals such as ... due to the growing demand for secure & simplified ... various ,sectors, such as hacking of bank accounts, misuse ... electronic equipment such as PC,s, laptops, and smartphones are ...
(Date:10/27/2015)... Synaptics Inc. (NASDAQ: SYNA ), the leader ... adopted the Synaptics ® ClearPad ® Series ... newest flagship smartphones, the Nexus 5X by LG and ... --> --> Synaptics works closely with ... in the joint development of next generation technologies. Together, ...
(Date:10/26/2015)... LAS VEGAS , Oct. 26, 2015 ... an innovator in modern authentication and a founding member ... launch of its latest version of the Nok Nok™ ... to use standards-based authentication that supports existing and emerging ... Suite is ideal for organizations deploying customer-facing applications that ...
Breaking Biology News(10 mins):
(Date:11/25/2015)... , ... November 25, 2015 , ... ... uBiome, were featured on AngelList early in their initial angel funding process. Now, ... syndicate for individuals looking to make early stage investments in the microbiome space. ...
(Date:11/24/2015)... (PRWEB) , ... November 24, 2015 , ... The United ... recipient of the 2016 USGA Green Section Award. Presented annually since 1961, the USGA ... his or her work with turfgrass. , Clarke, of Iselin, N.J., is ...
(Date:11/24/2015)... , Nov. 24, 2015 Halozyme Therapeutics, Inc. (NASDAQ: ... in New York on Wednesday, December 2 ... Torley , president and CEO, will provide a corporate overview. ... York at 1:00 p.m. ET/10:00 a.m. PT . ... relations, will provide a corporate overview. --> th ...
(Date:11/24/2015)... ... November 24, 2015 , ... ... But unless it is bound to proteins, copper is also toxic to cells. ... at Worcester Polytechnic Institute (WPI) will conduct a systematic study of copper in ...
Breaking Biology Technology:
Cached News: