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r circuit that is very similar in both species. Further identification of the targets of AMP-1 will be important in understanding how lifespan is regulated in animals and how it may be controlled and extended therapeutically.

Apfeld leaves us with some food for thought "In humans, AMP-1 is activated in muscle in response to exercise. It is tempting to speculate that perhaps some of the beneficial effects of exercise in human health are the result of the effect of AMP-1 activation on the aging process"


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Contact: Heather Cosel
coselpie@cshl.edu
Cold Spring Harbor Laboratory
2-Dec-2004


Page: 1 2

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