HOME >> BIOLOGY >> NEWS
Scientist honored with second-most cited research paper of the decade

Wladek Minor's busy laboratory inside Jordan Hall at the University of Virginia Health System is famous for strong cappuccino and European chocolates. But now there's something a lot bigger to crow about- the esteem of his competitive scientific colleagues around the world.

A professor of molecular physiology and biological physics and a native of Poland, Minor is a pioneer in the growing field of protein crystallography. His lab's work is not going unnoticed. A 1997 paper, "Processing of X-ray Differentiation Data Collected in Oscillation Mode," published with Zbyszek Otwinowski, a colleague at the University of Texas, is now the second-most cited scientific paper in the world in the last ten years, according to The Scientist magazine. The title may glaze the eyes of a layman, but the discovery is a building block of science and may one day help doctors treat cancer patients or people with viruses. "We are trying to elucidate the 3-dimensional structure of protein molecules which will hopefully lead to new cures for a host of diseases," Minor said.

Inside the Minor lab, a joyful polyglot of languages- Polish, Chinese, English- fills the air, usually seven days a week, amid chemical bottles, beakers, machines and microscopes. Minor's scientists use personal digital assistants (PDA's) connected to a central server to track all their experiments.

Minor and his ambitious team are tearing apart tiny proteins, trying to figure out the relationship between their structure and function. Their goal is to solve one of the greatest mysteries in intelligent drug design- how specific, targeted drugs can kill viruses or cancer cells by finding their way around the human body's complex chemistry and innumerable defenses.

The 1997 paper describes a computer program used to process the data coming from X-ray experiments made on protein crystals. The program is now used in over 1,200 laboratories worldwide and has been improved over the years. Mino
'"/>

Contact: Bob Beard
bobbeard@virginia.edu
434-982-4490
University of Virginia Health System
17-Jan-2006


Page: 1 2

Related biology news :

1. Scientists show that mitochondrial DNA variants are linked to risk factors for type 2 diabetes
2. Scientists prove that disputed Korean stem cell line comes from an unfertilized egg and not cloning
3. Scientists move closer to bio-engineered bladders
4. Scientists find stem cell switch
5. Scientists discover new way to study nanostructures
6. Scientists a step closer to understanding how anaesthetics work in the brain
7. Scientists to make news at Computational Biology Conference
8. Accident-prone? Scientists link brain function to knee injuries
9. Scientists take next step in understanding potential target for ovarian cancer treatment
10. Scientists find brown fat master switch
11. Scientists identify 2 distinct Parkinsons networks

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/20/2016)... 2016 Securus Technologies, a leading provider ... public safety, investigation, corrections and monitoring announced that ... has secured the final acceptance by all three ... Access Systems (MAS) installed. Furthermore, Securus will have ... installed by October, 2016. MAS distinguishes between legitimate ...
(Date:6/7/2016)... TORONTO , June 7, 2016  Syngrafii ... begun a business relationship that includes integrating Syngrafii,s ... pilot branch project. This collaboration will result in ... for the credit union, while maintaining existing document ... http://photos.prnewswire.com/prnh/20160606/375871LOGO ...
(Date:6/1/2016)... -- Favorable Government Initiatives Coupled With Implementation ... to Boost Global Biometrics System Market Through 2021  ... " Global Biometrics Market By Type, By End ... - 2021", the global biometrics market is projected to ... growing security concerns across various end use sectors such ...
Breaking Biology News(10 mins):
(Date:6/27/2016)... ... June 27, 2016 , ... Parallel 6 , the leading software ... Clinical Reach Virtual Patient Encounter CONSULT module which enables both audio and ... clinical trial team. , Using the CONSULT module, patients and physicians can schedule a ...
(Date:6/24/2016)... discussions on a range of subjects including policies, debt and ... Poloz. Speaking at a lecture to the Canadian ... to the country,s inflation target, which is set by both ... "In certain areas there needs to be ... why not sit down and address strategy together?" ...
(Date:6/23/2016)... , ... June 23, 2016 , ... ... pleased to announce the launch of their brand, UP4™ Probiotics, into Target stores ... 35 years, is proud to add Target to its list of well-respected retailers. ...
(Date:6/23/2016)... ... June 23, 2016 , ... Charm Sciences, Inc. is pleased ... received AOAC Research Institute approval 061601. , “This is another AOAC-RI approval of ... Salter, Vice President of Regulatory and Industrial Affairs. “The Peel Plate methods perform ...
Breaking Biology Technology:
Cached News: