HOME >> BIOLOGY >> NEWS
Scientist honored with second-most cited research paper of the decade

Wladek Minor's busy laboratory inside Jordan Hall at the University of Virginia Health System is famous for strong cappuccino and European chocolates. But now there's something a lot bigger to crow about- the esteem of his competitive scientific colleagues around the world.

A professor of molecular physiology and biological physics and a native of Poland, Minor is a pioneer in the growing field of protein crystallography. His lab's work is not going unnoticed. A 1997 paper, "Processing of X-ray Differentiation Data Collected in Oscillation Mode," published with Zbyszek Otwinowski, a colleague at the University of Texas, is now the second-most cited scientific paper in the world in the last ten years, according to The Scientist magazine. The title may glaze the eyes of a layman, but the discovery is a building block of science and may one day help doctors treat cancer patients or people with viruses. "We are trying to elucidate the 3-dimensional structure of protein molecules which will hopefully lead to new cures for a host of diseases," Minor said.

Inside the Minor lab, a joyful polyglot of languages- Polish, Chinese, English- fills the air, usually seven days a week, amid chemical bottles, beakers, machines and microscopes. Minor's scientists use personal digital assistants (PDA's) connected to a central server to track all their experiments.

Minor and his ambitious team are tearing apart tiny proteins, trying to figure out the relationship between their structure and function. Their goal is to solve one of the greatest mysteries in intelligent drug design- how specific, targeted drugs can kill viruses or cancer cells by finding their way around the human body's complex chemistry and innumerable defenses.

The 1997 paper describes a computer program used to process the data coming from X-ray experiments made on protein crystals. The program is now used in over 1,200 laboratories worldwide and has been improved over the years. Mino
'"/>

Contact: Bob Beard
bobbeard@virginia.edu
434-982-4490
University of Virginia Health System
17-Jan-2006


Page: 1 2

Related biology news :

1. Scientists show that mitochondrial DNA variants are linked to risk factors for type 2 diabetes
2. Scientists prove that disputed Korean stem cell line comes from an unfertilized egg and not cloning
3. Scientists move closer to bio-engineered bladders
4. Scientists find stem cell switch
5. Scientists discover new way to study nanostructures
6. Scientists a step closer to understanding how anaesthetics work in the brain
7. Scientists to make news at Computational Biology Conference
8. Accident-prone? Scientists link brain function to knee injuries
9. Scientists take next step in understanding potential target for ovarian cancer treatment
10. Scientists find brown fat master switch
11. Scientists identify 2 distinct Parkinsons networks

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Scientist honored with second most cited research paper the decade

(Date:8/25/2015)... SALT LAKE CITY and BELLEVUE, ... a global leader in advanced robotic systems, announced today ... first-of-its-kind robotic unmanned ground vehicle (UGV), at the National ... Lake City.  The Guardian S is ... is the culmination of years of research and in-field ...
(Date:8/20/2015)... 2015   Sensory, Inc ., a Silicon ... experience and security of consumer electronics through state-of-the-art ... its TrulySecure™ is the first multimodal ... FIDO Certified™. The FIDO (Fast Identification ... FIDO UAF (Universal Authentication Framework) 1.0 specifications, which ...
(Date:8/18/2015)... 17, 2015 Research and Markets ( ... "Global Biometric Authentication & Identification Market: Focus ... Forecast, 2015-2020" report to their offering. ... systems market is expected to grow at an ... and generate over $25 billion (approximately) by 2020 ...
Breaking Biology News(10 mins):Sarcos to Debut First-of-its-Kind Snake Robot 2Sarcos to Debut First-of-its-Kind Snake Robot 3TrulySecure From Sensory Becomes First Face and Voice Biometrics Technology to be FIDO UAF Certified 2TrulySecure From Sensory Becomes First Face and Voice Biometrics Technology to be FIDO UAF Certified 3TrulySecure From Sensory Becomes First Face and Voice Biometrics Technology to be FIDO UAF Certified 4TrulySecure From Sensory Becomes First Face and Voice Biometrics Technology to be FIDO UAF Certified 5Global Biometric Authentication & Identification Market 2015: Focus On Modality, Motility & Application - Estimation & Forecasts to 2020 for the $25 Billion Industry 2
(Date:8/31/2015)... , Aug. 31, 2015 Research and ... the "Israel Biomedical Sensors Market - Growth, Trends ... The Israel Biomedical Sensors market is estimated ... 3.73% over the period 2014-2020 The near ... the genetic formulation of each individual. These sensors can ...
(Date:8/31/2015)... SYDNEY , Aug. 31, 2015  US-Australian ... NVGN ) today confirmed its comprehensive scientific ... ground-breaking technology platforms in areas of unmet patient ... through the remaining preclinical projects prior to entering ... lead compounds. Acting Chief Executive Officer, ...
(Date:8/31/2015)... ... August 31, 2015 , ... Regulatory agencies have acknowledged ... development approval process. Thus, innovator companies must understand what will be needed in ... CMO, has been hosting multiple educational panels and seminars for experts to share ...
(Date:8/28/2015)... 2015 Research and Markets ... "Global & USA BioSimilar Market Analysis to 2021" ... awaited US Biosimilar market will be initiated in September ... How will the global market react? Will biosimilars explode ... could save the US economy up to $250 billion ...
Breaking Biology Technology:Israel Biomedical Sensors Market 2015 - Growth, Trends & Forecasts to 2020 2Novogen Announces The Outcome Of A Comprehensive Science Review 2Novogen Announces The Outcome Of A Comprehensive Science Review 3Novogen Announces The Outcome Of A Comprehensive Science Review 4Novogen Announces The Outcome Of A Comprehensive Science Review 5Novogen Announces The Outcome Of A Comprehensive Science Review 6Regis Shares Expert Advice on Impurities in Drug Development 2Regis Shares Expert Advice on Impurities in Drug Development 3Global & USA BioSimilar Market Analysis Report 2015-2021 2Global & USA BioSimilar Market Analysis Report 2015-2021 3
Cached News: