Scientists explore how complex organs develop from a simple bud

Durham, N.C. September 06, 2006 The current issue of Differentiation, guest-edited by Brigid Hogan, highlights several scientific investigations into the complex biological mechanism known as branching morphogenesis. Through a series of seven laboratory reviews, important insights governing this process during animal development are revealed. The articles analyze how branching morphogenesis occurs in different organ systems in the same species. They also compare the process between simple and complex organisms.

Key questions within the reviews --pertaining to the maintenance and repair of cells within adult branched organs, the role of cells only transiently associated with adult organs, and the extent to which defects in the growth and development of fetal stage organs can affect organ function after birth -- have important implications for human health.

Two of the reviews in the Journal delve into tubulogenesis a process that is intimately tied to branching morphogenesis. Another contains research aimed at helping patients whose salivary glands have been injured by radiation therapy or autoimmune rejection. An investigation into the morphogenesis of the prostate gland and seminal vesicles is included, as well as an in-depth look at the genetic and cellular interactions critical to placental development. Research on this process in mouse kidneys generated a real-time tracking procedure which has significant implications for genetic manipulation.

Ultimately, scientists hope analysis of branching morphogenesis will lead to the design of a computer program that is able to virtually reconstruct the complete process of organogenesis from simple bud to complex organ. The reviews in this special issue of Differentiation are written by top scientists offering fresh ideas and pertinent background information to readers interested in anything from molecular to cellular and developmental biology.


Contact: Sean Wagner
Blackwell Publishing Ltd.

Page: 1

Related biology news :

1. Scientists show that mitochondrial DNA variants are linked to risk factors for type 2 diabetes
2. Scientists prove that disputed Korean stem cell line comes from an unfertilized egg and not cloning
3. Scientists move closer to bio-engineered bladders
4. Scientists find stem cell switch
5. Scientists discover new way to study nanostructures
6. Scientists a step closer to understanding how anaesthetics work in the brain
7. Scientists to make news at Computational Biology Conference
8. Accident-prone? Scientists link brain function to knee injuries
9. Scientists take next step in understanding potential target for ovarian cancer treatment
10. Scientists find brown fat master switch
11. Scientists identify 2 distinct Parkinsons networks

Post Your Comments:
TAG: Scientists explore how complex organs develop from simple bud

(Date:10/2/2015)... DUBLIN , Oct. 02 2015 ... addition of the "Enforcing the Law Using ... http://www.researchandmarkets.com/research/6kp5mx/enforcing_the_law ) has announced the addition of ... report to their offering. --> Research ... addition of the "Enforcing the Law Using ...
(Date:9/30/2015)... global glucose monitoring device and diabetes management market is valued ... on the industry from Kalorama Information. Sales in the traditional glucose ... continuous glucose monitoring and sensor segment, according to the healthcare ... in its latest report, The Global Glucose Monitoring Market ... , ...
(Date:9/28/2015)...  The monitoring of vital signs, such as ... an essential component of patient assessment. Changes in ... a patient,s condition. However, in general care areas ... during routine observation rounds only once every four ... these observation rounds, the warning signs can go ...
Breaking Biology News(10 mins):
(Date:10/9/2015)... HERSHEY, Pa. and ROCKVILLE, ... Therapeutics, Inc. ("ITI"), a privately-held biotechnology company developing ... today announced that it has entered into an ... on LAMP-vax products for the treatment or prevention ... Upon execution of the agreement, Immunomic Therapeutics will ...
(Date:10/9/2015)... ... October 09, 2015 , ... Leading microbial genomics startup uBiome ... better understand the relationship between weight management and the microbiome. The study uses the ... participants using an iPhone app. , The uBiome app is available as a free ...
(Date:10/8/2015)... N.J. , Oct. 8, 2015  Genetic testing ... may aid the identification of more couples at risk ... a study presented today at the 2015 American Society ... October 10 in Baltimore, Maryland . ... Quest Diagnostics (NYSE: DGX ) are presenting at ...
(Date:10/8/2015)... , October 8, 2015 ... .   --> Goldman Small Cap ... the small cap and microcap sectors, announced today ... report on PharmaCyte Biotech, Inc. (OTCQB - PMCB), ... on developing and preparing treatments for cancer and ...
Breaking Biology Technology:
Cached News: