HOME >> BIOLOGY >> NEWS
Scientists find a maturity gene

University of Utah researchers showed that a fruit fly gene is crucial for determining when juveniles begin to mature into adults, and how the transformation initially proceeds. Understanding this process in humans may help explain how adorable children become surly teenagers.

When the DHR4 gene is disabled, fruit flies prematurely begin metamorphosis maturation from an immature larva to a sexually active adult. It is the first genetic mutation found to cause early maturation in fruit flies, according to a new study in the Friday June 3 issue of the journal Cell. The flies are abnormally small and die as they enter adulthood, sometimes when their heads fail to emerge from their bodies.

"We identified a gene that is needed for the animal to progress through normal juvenile development to maturation," says University of Utah geneticist Carl Thummel, the study's principal author. "Without this gene, the juvenile stage is shortened, and it enters adulthood early. The animal then dies because the gene also is needed for continued maturation."

The process is relevant to people because insect metamorphosis is analogous to the transformation of a human "from a juvenile, non-reproductive stage to a mature, sexually reproductive adult," says Thummel, a professor of human genetics at the university and an investigator with the Howard Hughes Medical Institute.

"Our kids stay sweet and cute through about 12 years of life and then, suddenly, in response to steroid and thyroid hormones and their receptors [molecules that help hormones control genes], they begin this amazing transformation into smelly, hairy, sometimes surly, sexually mature teenagers," he adds. "How is this event timed, and how is it controlled at a molecular [genetic] level? Clearly there is genetic input, since the timing of maturation varies between families and cultures. But molecular mechanisms are presently unknown. Our study addresses this question using fruit flies,
'"/>

Contact: Lee Siegel
leesiegel@ucomm.utah.edu
801-581-8993
University of Utah Health Sciences Center
2-Jun-2005


Page: 1 2 3 4 5

Related biology news :

1. Scientists show that mitochondrial DNA variants are linked to risk factors for type 2 diabetes
2. Scientists prove that disputed Korean stem cell line comes from an unfertilized egg and not cloning
3. Scientists move closer to bio-engineered bladders
4. Scientists find stem cell switch
5. Scientists discover new way to study nanostructures
6. Scientists a step closer to understanding how anaesthetics work in the brain
7. Scientists to make news at Computational Biology Conference
8. Accident-prone? Scientists link brain function to knee injuries
9. Scientists take next step in understanding potential target for ovarian cancer treatment
10. Scientists find brown fat master switch
11. Scientists identify 2 distinct Parkinsons networks

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/8/2019)... ... 2019 , ... FISO Technologies proudly presents the innovative FOP-M200, ... fiber of 100 microns. With dimensions smaller than any competitive product, FISO is ... leader in the development of fiber optic sensors & signal conditioners used in ...
(Date:5/2/2019)... ... 2019 , ... Philadelphia intellectual property law firm Panitch ... Ph.D., a registered patent agent, has joined the firm as a new member ... technical support and scientific expertise in the pharmaceutical and biotechnical arts and assists ...
(Date:5/2/2019)... ... May 01, 2019 , ... uBiome, the leader in microbial ... Company’s General Counsel, as Interim Chief Executive Officer of uBiome, effective immediately. The ... leave. There will also be an independent investigation into uBiome’s billing practices to ...
Breaking Biology News(10 mins):
(Date:4/18/2019)... ... April 18, 2019 , ... ... team that includes a chemical engineer at Worcester Polytechnic Institute (WPI) has developed ... make it possible to manufacture isobutanol and other biofuels more economically. , Isobutanol, ...
(Date:4/10/2019)... ... April 10, 2019 , ... ... locked into multiple agreements to help companies advance their innovations to clinical ... ranging from synthetic biology companies that are gene editing therapeutic cells for ...
(Date:4/8/2019)... ... April 08, 2019 , ... ... solutions, announced today the launch of their app integration solution, CT Cloud Unite. ... and contact-orientated applications while using CT Cloud Voice and Skype for Business solutions. ...
(Date:3/29/2019)... ... March 28, 2019 , ... Specific ... CARB-X has proceeded with a second stage of funding for Specific’s Reveal™ rapid ... is on top of the $1.7 million already awarded by CARB-X. The additional ...
Breaking Biology Technology:
Cached News: