HOME >> BIOLOGY >> NEWS
Scientists prove that disputed Korean stem cell line comes from an unfertilized egg and not cloning

Can a genetic signature identify the origin of a human stem cell line? Scientists report that a widely available method for comprehensive genetic analysis can help distinguish the type of human embryo that stem cells come from. The research, to be published online August 2nd by the journal Cell Stem Cell, published by Cell Press, also provides an intriguing new insight into the largest scandal in the history of human stem cell research.

Different methods can be used to make embryonic stem (ES) cells. Human ES cells are typically made from embryos that are donated by couples that have undergone in vitro fertilization as a form of assisted reproduction therapy for infertility. Parthenogenetic ES (pES) cells are derived from embryos created by artificial activation of eggs in the absence of sperm. ES cells generated by somatic nuclear transfer (ntES) are derived from embryos that are created when the nucleus of an egg is replaced by the nucleus from a body cell. Creation of human ntES are pES are of particular interest to researchers as they may provide stem cells that are nearly genetically identical to the donor and, therefore, particularly well suited for customized, rejection-proof cell transplantation therapies.

To better understand the specific genetic recombination events that occur in ES cells derived by these different methods, researchers under the direction of Dr. George Q. Daley of Childrens Hospital Boston and the Harvard Stem Cell Institute together with an international set of collaborators completed a thorough genome-wide analysis of five novel pES cells, 30 mouse ntES, as well as the SCNT-hES-1 cell line, the first human ES cell line purportedly generated by Korean scientists using human eggs and somatic cell nuclear transfer. The original paper describing the SCNT-hES-1 cell line was retracted after an investigation by the Seoul National University revealed research misconduct, but the derivation of the cell line was never fully
'"/>

Contact: Erin Doonan
edoonan@cell.com
617-397-2802
Cell Press
2-Aug-2007


Page: 1 2

Related biology news :

1. Scientists show that mitochondrial DNA variants are linked to risk factors for type 2 diabetes
2. Scientists move closer to bio-engineered bladders
3. Scientists find stem cell switch
4. Scientists discover new way to study nanostructures
5. Scientists a step closer to understanding how anaesthetics work in the brain
6. Scientists to make news at Computational Biology Conference
7. Accident-prone? Scientists link brain function to knee injuries
8. Scientists take next step in understanding potential target for ovarian cancer treatment
9. Scientists find brown fat master switch
10. Scientists identify 2 distinct Parkinsons networks
11. Scientists follow familiar TRAIL to new cancer therapy

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/13/2020)... ... February 13, 2020 , ... ... with Nobio CEO Yoram Ashery to discuss how their revolutionary technology ... that combats bacteria to keep people healthy with their revolutionary nanoparticle technology. Nobio ...
(Date:2/11/2020)... ... February 11, 2020 , ... ... The LaunchPort™ medical device accelerator in Port Covington, Baltimore. The newly formed company ... must be addressed to manage increased demand for home dialysis treatments. The start-up ...
(Date:2/6/2020)... NEW YORK (PRWEB) , ... ... ... global, full-service clinical research organization (CRO) specializing in complex interventional medical device ... as Vice President, Regulatory Strategy. In this newly established role, Dorothy oversees ...
Breaking Biology News(10 mins):
(Date:2/21/2020)... ... February 20, 2020 , ... The dietary supplement industry now ... what’s listed on an ingredient panel is actually in their product. As ... the adoption of CertainT, which is designed to protect the intellectual property (IP) ...
(Date:2/21/2020)... ... 21, 2020 , ... Pharmaceutical manufacturers are under increasing pressure ... to new approaches like ‘Industry 4.0’ and continuous manufacturing, combat the growing and ... therapies. But with an industry with the world’s tightest regulations and complex value ...
(Date:2/19/2020)... ... February 18, 2020 , ... Intech , the ... a new and unified global brand identity, as it celebrates its 20th anniversary. ... as well as an enthusiasm for designing and manufacturing state-of-the-art medical devices, Intech ...
(Date:2/13/2020)... ... 12, 2020 , ... Arriello , a provider of ... Veeva Vault Safety™ as part of the company’s continued growth in pharmacovigilance ... of safety information such as SUSARs and ICSRS, aggregate report production, signal management, ...
Breaking Biology Technology:
Cached News: