HOME >> BIOLOGY >> NEWS
Scientists unpick genetics of first 15 minutes of life

Scientists have identified the gene responsible for controlling a first key step in the creation of new life, according to new research published in the journal Nature tomorrow (Thursday 27 October 2005).

The gene, known as HIRA, 'chaperones' the early processes that take place once a sperm enters an egg, giving it a crucial role in the most fundamental process in sexually reproducing animals.

The absence or mutation of this gene in the maternal (mother's) genome explains why eggs fail to produce a zygote or early embryo - despite the presence of 'healthy' sperm.

Although the researchers use the fruit fly Drosophila melanogaster to discover the basic genetic processes of sex, the same genetic processes are present in all sexually reproducing animals, including humans.

"All sexually reproducing animals do the same kind of DNA 'dance' when the DNA from the mother's egg cell and the father's sperm cell meet for the first time," said Dr Tim Karr from the University of Bath (UK) who worked closely with Drs Benjamin Loppin and Pierre Couble from Centre de Gntique Molculaire et Cellulaire (France) on the project.

"When the sperm enters the egg, the DNA it carries needs to be re-packaged so that it can engage in normal cellular activities, including combining with the maternal DNA in the first act of genetic fertilisation.

"A single gene, HIRA, looks after this re-packaging process, making it fundamental for those first 15 minutes in the regeneration of a new life."

When sperm cells are created, the molecule that the sperm DNA is wrapped around (called chromatin) is remodelled by swapping the type of 'packing material', known as histone proteins, it contains.

When it arrives at the egg cell, however, the sperm DNA needs to be re-packaged with a new set of histone proteins so that the sperm DNA can engage in normal cellular activities. The result is called the male pro-nucleus.

To understand how this pr
'"/>

Contact: Andrew McLaughlin
a.mclaughlin@bath.ac.uk
44-1-225-386-883
University of Bath
26-Oct-2005


Page: 1 2

Related biology news :

1. Scientists show that mitochondrial DNA variants are linked to risk factors for type 2 diabetes
2. Scientists prove that disputed Korean stem cell line comes from an unfertilized egg and not cloning
3. Scientists move closer to bio-engineered bladders
4. Scientists find stem cell switch
5. Scientists discover new way to study nanostructures
6. Scientists a step closer to understanding how anaesthetics work in the brain
7. Scientists to make news at Computational Biology Conference
8. Accident-prone? Scientists link brain function to knee injuries
9. Scientists take next step in understanding potential target for ovarian cancer treatment
10. Scientists find brown fat master switch
11. Scientists identify 2 distinct Parkinsons networks

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Scientists unpick genetics first minutes life

(Date:4/8/2015)... CHARLOTTE, N.C. , April 8, 2015 /PRNewswire/ ... technology solutions and services, and Morpho, a leading ... in partnership to produce the market,s most advanced ... Infinisource,s iSolved NXG time clock is setting ... attendance and labor data for the small and ...
(Date:4/2/2015)... Sweden , April 2, 2015 ... its touch fingerprint sensor FPC1025 from the distributor World ... will commence during Q2 2015 although the major part ... The sensors will be used by smartphone manufacturers in ... 110 MSEK is included in the communicated revenue guidance ...
(Date:3/30/2015)... 2015 Research and Markets ( http://www.researchandmarkets.com/research/lc9bnl/global_gesture ... Gesture Recognition Market in Automotive Sector 2014-2018" report ... Global Gesture Recognition market in Automotive Sector to grow ... Gesture recognition is the ability of a ... an individual. Gesture recognition technology can be 2D-based or ...
Breaking Biology News(10 mins):iSolved Time Clock Offers Unmatched Accuracy due to Morpho Biometrics 2iSolved Time Clock Offers Unmatched Accuracy due to Morpho Biometrics 3Fingerprint Cards Receives Touch Fingerprint Sensor Order of SEK 110 Million 2Global Gesture Recognition Market in Automotive Sector Report 2015 - Growing Number of Partnerships 2
(Date:4/23/2015)... , April 23, 2015  Cryoport, Inc. (OTCBB: ... logistics solutions for the life sciences industry, today ... cryogenic logistics solutions within the animal husbandry market ... Farms to support the shipment of equine semen ... horse Stallions. Animal husbandry is ...
(Date:4/23/2015)... -- Metanome, Inc., an industry leader in comprehensive microbiome ... name to Diversigen, Inc.  The name was changed ... source for the myriad of services and expertise ... of the microbiome.  From the wide diversity in ... that are difficult to handle, such as low ...
(Date:4/22/2015)...  The Heinz Family Foundation today announced the ... which will present unrestricted cash awards totaling $1.25 ... and determination in finding solutions to critical issues ... recipients include a prolific cartoonist whose quirky characters ... relationships; two former Marines who are re-engaging veterans ...
(Date:4/22/2015)... , April 22, 2015 Steep ... analytics, announced today that it has opened an ... continued growth and expansion.  The common stock investment ... Section 506(c), a law intended to encourage funding ... Prior to 506(c), small businesses largely relied on ...
Breaking Biology Technology:Cryoport to Support the Equine Animal Husbandry Market Through Agreement with Yancey Farms 2Cryoport to Support the Equine Animal Husbandry Market Through Agreement with Yancey Farms 3Metanome Announces Corporate Name Change to Diversigen 2From a Scientist Who Develops Human Microlivers to a New Yorker Cartoonist Who Masterfully Depicts the Humor and Heartbreak of Everyday Life: The 20th Heinz Awards Honors Six Changemakers 2From a Scientist Who Develops Human Microlivers to a New Yorker Cartoonist Who Masterfully Depicts the Humor and Heartbreak of Everyday Life: The 20th Heinz Awards Honors Six Changemakers 3From a Scientist Who Develops Human Microlivers to a New Yorker Cartoonist Who Masterfully Depicts the Humor and Heartbreak of Everyday Life: The 20th Heinz Awards Honors Six Changemakers 4From a Scientist Who Develops Human Microlivers to a New Yorker Cartoonist Who Masterfully Depicts the Humor and Heartbreak of Everyday Life: The 20th Heinz Awards Honors Six Changemakers 5From a Scientist Who Develops Human Microlivers to a New Yorker Cartoonist Who Masterfully Depicts the Humor and Heartbreak of Everyday Life: The 20th Heinz Awards Honors Six Changemakers 6Steep Hill Launches $5M Limited Stock Offering 2Steep Hill Launches $5M Limited Stock Offering 3
Cached News: