HOME >> BIOLOGY >> NEWS
Scientists unpick genetics of first 15 minutes of life

Scientists have identified the gene responsible for controlling a first key step in the creation of new life, according to new research published in the journal Nature tomorrow (Thursday 27 October 2005).

The gene, known as HIRA, 'chaperones' the early processes that take place once a sperm enters an egg, giving it a crucial role in the most fundamental process in sexually reproducing animals.

The absence or mutation of this gene in the maternal (mother's) genome explains why eggs fail to produce a zygote or early embryo - despite the presence of 'healthy' sperm.

Although the researchers use the fruit fly Drosophila melanogaster to discover the basic genetic processes of sex, the same genetic processes are present in all sexually reproducing animals, including humans.

"All sexually reproducing animals do the same kind of DNA 'dance' when the DNA from the mother's egg cell and the father's sperm cell meet for the first time," said Dr Tim Karr from the University of Bath (UK) who worked closely with Drs Benjamin Loppin and Pierre Couble from Centre de Gntique Molculaire et Cellulaire (France) on the project.

"When the sperm enters the egg, the DNA it carries needs to be re-packaged so that it can engage in normal cellular activities, including combining with the maternal DNA in the first act of genetic fertilisation.

"A single gene, HIRA, looks after this re-packaging process, making it fundamental for those first 15 minutes in the regeneration of a new life."

When sperm cells are created, the molecule that the sperm DNA is wrapped around (called chromatin) is remodelled by swapping the type of 'packing material', known as histone proteins, it contains.

When it arrives at the egg cell, however, the sperm DNA needs to be re-packaged with a new set of histone proteins so that the sperm DNA can engage in normal cellular activities. The result is called the male pro-nucleus.

To understand how this pr
'"/>

Contact: Andrew McLaughlin
a.mclaughlin@bath.ac.uk
44-1-225-386-883
University of Bath
26-Oct-2005


Page: 1 2

Related biology news :

1. Scientists show that mitochondrial DNA variants are linked to risk factors for type 2 diabetes
2. Scientists prove that disputed Korean stem cell line comes from an unfertilized egg and not cloning
3. Scientists move closer to bio-engineered bladders
4. Scientists find stem cell switch
5. Scientists discover new way to study nanostructures
6. Scientists a step closer to understanding how anaesthetics work in the brain
7. Scientists to make news at Computational Biology Conference
8. Accident-prone? Scientists link brain function to knee injuries
9. Scientists take next step in understanding potential target for ovarian cancer treatment
10. Scientists find brown fat master switch
11. Scientists identify 2 distinct Parkinsons networks

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Scientists unpick genetics first minutes life

(Date:5/28/2015)... , May 28, 2015 Industry ... of a new report titled "Markets for Self-Healing ... polymers, inorganic capsule and vascular systems, biomaterials, relevant ... grow to around $2.7 billion by 2020. ... n-tech,s extensive coverage of smart materials. Other recent n-tech ...
(Date:5/27/2015)...   Codonics (codonics.com), a global ... documentation solutions and Omnicell  (omnicell.com), a ... is pleased to announce their state of ... System® (SLS), an award-winning FDA class 2 ... Anesthesia Workstation, helps prevent medication errors, streamlines ...
(Date:5/26/2015)... May 26, 2015 Research ... addition of the "Saudi Arabia Biometric Systems ... their offering. ,     (Logo: http://photos.prnewswire.com/prnh/20130307/600769) , ,The biometric ... is projected to grow at over 22% ... is attributed to the surging demand for better ...
Breaking Biology News(10 mins):The Market for Self-Healing Materials to Reach $2.7 Billion by 2020 Says New n-tech Research Study 2The Market for Self-Healing Materials to Reach $2.7 Billion by 2020 Says New n-tech Research Study 3Codonics and Omnicell Expand Partnership 2Codonics and Omnicell Expand Partnership 3Codonics and Omnicell Expand Partnership 4Saudi Arabia Biometric Systems Market Forecast and Opportunities, 2020 with Morpho Safran, ZK Technlogy, and Suprema Dominating 2
(Date:5/28/2015)... 2015 Research and ... of Jain PharmaBiotech,s new report  "Alzheimer Disease ... their offering.       (Logo: http://photos.prnewswire.com/prnh/20130307/600769) ... in management. With nearly 8 million sufferers ... markets of the world and anticipated increases ...
(Date:5/28/2015)... DUBLIN , May 28, 2015 /PRNewswire/ ... http://www.researchandmarkets.com/research/7k46bt/therapeutic_drug ) has announced the addition of ... Monitoring - Technologies, Markets, and Companies" ... http://photos.prnewswire.com/prnh/20130307/600769) , This report deals ... specialty, aimed at improving patient care by ...
(Date:5/28/2015)... N.J. , May 28, 2015  Quest Diagnostics ... of diagnostic information services, announced that it is scheduled ... in New York.  Steve Rusckowski , the company,s ... and five point strategy.  The presentation is scheduled for ... The presentation will be webcast live during ...
(Date:5/28/2015)... May 28, 2015 ... has announced the addition of Jain ... Technologies, Markets and Companies"  to their ... report describes and evaluates animal biotechnology ... and pharmaceuticals as well as improvement ...
Breaking Biology Technology:Global Alzheimer Disease Report 2015-2024 - New Drugs, Markets and Companies 2Global Alzheimer Disease Report 2015-2024 - New Drugs, Markets and Companies 3Global Therapeutic Drug Monitoring Market 2015-2024 2Quest Diagnostics to Speak at the Jefferies 2015 Global Healthcare Conference 2Global Animal Biotechnology Report 2015 - Technologies, Markets and Companies Analysis to 2024 2Global Animal Biotechnology Report 2015 - Technologies, Markets and Companies Analysis to 2024 3
Cached News: