HOME >> BIOLOGY >> NEWS
Scientists unpick genetics of first 15 minutes of life

Scientists have identified the gene responsible for controlling a first key step in the creation of new life, according to new research published in the journal Nature tomorrow (Thursday 27 October 2005).

The gene, known as HIRA, 'chaperones' the early processes that take place once a sperm enters an egg, giving it a crucial role in the most fundamental process in sexually reproducing animals.

The absence or mutation of this gene in the maternal (mother's) genome explains why eggs fail to produce a zygote or early embryo - despite the presence of 'healthy' sperm.

Although the researchers use the fruit fly Drosophila melanogaster to discover the basic genetic processes of sex, the same genetic processes are present in all sexually reproducing animals, including humans.

"All sexually reproducing animals do the same kind of DNA 'dance' when the DNA from the mother's egg cell and the father's sperm cell meet for the first time," said Dr Tim Karr from the University of Bath (UK) who worked closely with Drs Benjamin Loppin and Pierre Couble from Centre de Gntique Molculaire et Cellulaire (France) on the project.

"When the sperm enters the egg, the DNA it carries needs to be re-packaged so that it can engage in normal cellular activities, including combining with the maternal DNA in the first act of genetic fertilisation.

"A single gene, HIRA, looks after this re-packaging process, making it fundamental for those first 15 minutes in the regeneration of a new life."

When sperm cells are created, the molecule that the sperm DNA is wrapped around (called chromatin) is remodelled by swapping the type of 'packing material', known as histone proteins, it contains.

When it arrives at the egg cell, however, the sperm DNA needs to be re-packaged with a new set of histone proteins so that the sperm DNA can engage in normal cellular activities. The result is called the male pro-nucleus.

To understand how this pr
'"/>

Contact: Andrew McLaughlin
a.mclaughlin@bath.ac.uk
44-1-225-386-883
University of Bath
26-Oct-2005


Page: 1 2

Related biology news :

1. Scientists show that mitochondrial DNA variants are linked to risk factors for type 2 diabetes
2. Scientists prove that disputed Korean stem cell line comes from an unfertilized egg and not cloning
3. Scientists move closer to bio-engineered bladders
4. Scientists find stem cell switch
5. Scientists discover new way to study nanostructures
6. Scientists a step closer to understanding how anaesthetics work in the brain
7. Scientists to make news at Computational Biology Conference
8. Accident-prone? Scientists link brain function to knee injuries
9. Scientists take next step in understanding potential target for ovarian cancer treatment
10. Scientists find brown fat master switch
11. Scientists identify 2 distinct Parkinsons networks

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/22/2016)... , June 22, 2016  The American College of Medical ... Show Executive Magazine as one of the fastest-growing trade ... 25-27 at the Bellagio in Las Vegas ... highest percentage of growth in each of the following categories: ... companies and number of attendees. The 2015 ACMG Annual Meeting ...
(Date:6/22/2016)... , June 22, 2016   ... management and verification solutions, has partnered with ... software solutions for Visitor Management, Self-Service Kiosks ... provides products that add functional enhancements to ... provides corporations and venues with an automated ...
(Date:6/22/2016)... On Monday, the Department of Homeland Security ... solutions for the Biometric Exit Program. The Request for ... (CBP), explains that CBP intends to add biometrics to ... United States , in order to deter visa ... Logo - http://photos.prnewswire.com/prnh/20160622/382209LOGO ...
Breaking Biology News(10 mins):
(Date:6/27/2016)... ... June 27, 2016 , ... ... on what they believe could be a new and helpful biomarker for malignant ... Click here to read it now. , Biomarkers are components in ...
(Date:6/27/2016)... ... 2016 , ... Parallel 6 , the leading software as a service ... Virtual Patient Encounter CONSULT module which enables both audio and video telemedicine communication ... , Using the CONSULT module, patients and physicians can schedule a face to face ...
(Date:6/27/2016)... ... June 27, 2016 , ... Newly created ... services and solutions to the healthcare market. The company's primary focus is on ... sales and marketing strategies that are necessary to help companies efficiently bring their ...
(Date:6/27/2016)... Hill, N.C. (PRWEB) , ... June 27, 2016 ... ... U.S. commercial operations for Amgen, will join the faculty of the University ... serve as adjunct professor of strategy and entrepreneurship at UNC Kenan-Flagler, with a ...
Breaking Biology Technology:
Cached News: