HOME >> BIOLOGY >> NEWS
Sea creature's toxin could lead to promising cancer treatment

tinguishable in its biological action, but is easier to synthesize in the lab.

The researchers tested AB-5's effectiveness against cancer by implanting human tumor cells under the skin of m ice and treating them with either paclitaxel (Taxol) or vinblastine both approved drugs currently used or AB-5. The trial used tumor cells from human prostate, breast and colon cancers.

While all three drugs reduced tumors in the mice, the known drugs caused significant weight loss and loss of white blood cells while AB-5 caused neither side effect. "That the diazonamide toxin blocks mitosis selectively in cancer cells is almost too desirable an outcome to be true," said Dr. Steven McKnight, chairman of biochemistry and senior author of the second study. "As with any other unanticipated scientific discovery, the validity of these observations will be held to appropriately diligent scrutiny."


'"/>

Contact: Aline McKenzie
aline.mckenzie@utsouthwestern.edu
214-648-3404
UT Southwestern Medical Center
5-Feb-2007


Page: 1 2 3

Related biology news :

1. New use for a cell toxin found to inhibit survival proteins in cancer cells
2. Children of smokers have more than 5 times higher levels of a nicotine toxin
3. Genome of Clostridium botulinum reveals the background to worlds deadliest toxin
4. Engineered protein effective against Staphylococcus aureus toxin
5. Anthrax paralyzes immune cells with lethal toxin, UF research shows
6. Gene that governs toxin production in deadly mold found
7. Bacterial response to oxidation studied as toxin barometer
8. Scripps research scientists: Compounds show significant promise against potential bioweapon toxins
9. Algae toxin identification unravels fish-kill mystery
10. Red tide toxins leave beachgoers breathless
11. Study reveals molecular basis of botulism toxins deadly activity

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Sea creature toxin could lead promising cancer treatment

(Date:10/27/2014)... CA – October 28, 2014 – A new randomized ... proprietary blend of collagen and calcium, KoACT®, was far ... the leaching of calcium from bones and rebuilding new ... PubMed at: http://www.ncbi.nlm.nih.gov/pubmed/25314004 , ahead of print in ... The research was conducted by Bahram H. Arjmandi, PhD, ...
(Date:10/27/2014)... 2014 NXT-ID, Inc. (NASDAQ: NXTD ... authentication company focused on the growing mobile commerce market ... Tunnell , Chief Technology Officer. Mr Tunnell examines the ... With the variety of new payment solutions being ... payment method has its own attributes that promise to ...
(Date:10/27/2014)... October 27, 2014—New results from a safety and ... test efficacy, indicate that a live attenuated enterotoxigenic ... in combination with a novel adjuvant, provided significant ... data for this vaccine/adjuvant combination, which was 58.5 ... severity using a highly rigorous ETEC human challenge ...
Breaking Biology News(10 mins):New RCT: KoACT® beats calcium and vitamin D for optimal bone strength 2Media Alert; NXT-ID Chief Technology Officer Comments on Why You Need a Smart Wallet 2Media Alert; NXT-ID Chief Technology Officer Comments on Why You Need a Smart Wallet 3Media Alert; NXT-ID Chief Technology Officer Comments on Why You Need a Smart Wallet 4Clinical results indicate vaccine candidate highly efficacious against bacterial diarrhea 2
(Date:10/26/2014)... The report "Protective Coatings Market by Resin ... & Forecast to 2019", defines and segments the global ... consumed and value generated. The protective coatings consumption is ... 6,701.3 KT by 2019, at a CAGR of 9.52% ... tables and 22 figures spread through 219 slides and ...
(Date:10/25/2014)... 23, 2014 ViaDerma, Inc ... company devoted to bringing new products to market, ... , ViaDerma has developed an innovative, patent-pending dual ... mass transfer of pharmaceutical active ingredients to penetrate ... immediate localized therapy. The transdermal delivery method also ...
(Date:10/25/2014)... According to new market research report "Data ... Enterprise, Telecom), by Design Types (Electrical, Mechanical), and ... 3, Tier 4) - Global Forecast to 2019", ... Center Construction Market into various segments with an ... report also identifies the factors driving this market, ...
(Date:10/25/2014)... 24, 2014 The Workgroup ... leading nonprofit authority on the use of health ... announces its appointment of four new co-chairs to ... leaders include:, ,     Peter Dumont, Senior ... Pupo, Specialist Leader, Deloitte Consulting LLP , ...
Breaking Biology Technology:Protective Coatings Market Poised to Reach $18,431.8 Million by 2019 - Report by MarketsandMarkets 2Protective Coatings Market Poised to Reach $18,431.8 Million by 2019 - Report by MarketsandMarkets 3Protective Coatings Market Poised to Reach $18,431.8 Million by 2019 - Report by MarketsandMarkets 4ViaDerma, Inc. Announces Plans to Pursue Out-Licensing Partnerships in 2015 2ViaDerma, Inc. Announces Plans to Pursue Out-Licensing Partnerships in 2015 3Data Center Construction Market Worth $22.73 Billion by 2019 - New Report by MarketsandMarkets 2Data Center Construction Market Worth $22.73 Billion by 2019 - New Report by MarketsandMarkets 3Data Center Construction Market Worth $22.73 Billion by 2019 - New Report by MarketsandMarkets 4WEDI Appoints Four New Security and Privacy Workgroup Co-chairs 2
Cached News: