HOME >> BIOLOGY >> NEWS
Sea creature's toxin could lead to promising cancer treatment

tinguishable in its biological action, but is easier to synthesize in the lab.

The researchers tested AB-5's effectiveness against cancer by implanting human tumor cells under the skin of m ice and treating them with either paclitaxel (Taxol) or vinblastine both approved drugs currently used or AB-5. The trial used tumor cells from human prostate, breast and colon cancers.

While all three drugs reduced tumors in the mice, the known drugs caused significant weight loss and loss of white blood cells while AB-5 caused neither side effect. "That the diazonamide toxin blocks mitosis selectively in cancer cells is almost too desirable an outcome to be true," said Dr. Steven McKnight, chairman of biochemistry and senior author of the second study. "As with any other unanticipated scientific discovery, the validity of these observations will be held to appropriately diligent scrutiny."


'"/>

Contact: Aline McKenzie
aline.mckenzie@utsouthwestern.edu
214-648-3404
UT Southwestern Medical Center
5-Feb-2007


Page: 1 2 3

Related biology news :

1. New use for a cell toxin found to inhibit survival proteins in cancer cells
2. Children of smokers have more than 5 times higher levels of a nicotine toxin
3. Genome of Clostridium botulinum reveals the background to worlds deadliest toxin
4. Engineered protein effective against Staphylococcus aureus toxin
5. Anthrax paralyzes immune cells with lethal toxin, UF research shows
6. Gene that governs toxin production in deadly mold found
7. Bacterial response to oxidation studied as toxin barometer
8. Scripps research scientists: Compounds show significant promise against potential bioweapon toxins
9. Algae toxin identification unravels fish-kill mystery
10. Red tide toxins leave beachgoers breathless
11. Study reveals molecular basis of botulism toxins deadly activity

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Sea creature toxin could lead promising cancer treatment

(Date:7/29/2014)... from scientists at the University of Kent has shown ... are regulated a breakthrough that could have a ... from Kent,s School of Biosciences uncovered the mechanism whereby ... known as actin filaments are ,fine-tuned, to ... filaments appear to completely stable, providing a framework for ...
(Date:7/29/2014)... affects 1 in 100,000 people characterized by a loss ... remains unknown, a new study by a team of researchers ... Germany and other European institutions confirms for the first time ... 6 July in Nature Genetics , is an important ... a sphincter in the lower esophagus opens, allowing food to ...
(Date:7/28/2014)... Amundsen reached the South Pole in 1911, but new ... any human. , Using data from 16 ice cores ... including the South Pole, a group led by Joe ... Nevada, created the most accurate and precise reconstruction to ... new record, described in an article published today in ...
Breaking Biology News(10 mins):Mysterious esophagus disease is autoimmune after all 2Lead pollution beat explorers to South Pole, persists today 2Lead pollution beat explorers to South Pole, persists today 3
(Date:7/29/2014)... , July 29, 2014 ... surgical equipment market (types, applications and geography) - Size, ... Report, Opportunities, Segmentation and Forecast, 2013 - 2020", suggests ... reach $12.1 billion by 2020 registering a CAGR of ... the breakthrough achieved by the electro surgical devices in ...
(Date:7/29/2014)... Hershey, PA & Rockville, MD (PRWEB) July 29, ... Immunomic Therapeutics, Inc. (ITI), a vaccine pioneer in ... the financial services firm Newport Coast Securities, Inc. ... , ITI is commercializing LAMP-vax technology, a breakthrough ... $25B+ vaccines and immunotherapy market. The company exclusively ...
(Date:7/29/2014)... DisasterTalk is a texting app which allows ... masts or other transmitters are down. The app can transmit ... the need for any Wi-Fi, and can also use a ... app has launched as a housing report finds ... risk of being affected by natural disasters. With the risk ...
(Date:7/29/2014)... California (PRWEB) July 29, 2014 The ... is a next generation approach to robotics. What sets ... is patent pending technology that allows them to communicate, ... all wirelessly over the internet. , “The invention is ... giving the little Droidles a life of their own, ...
Breaking Biology Technology:Global Surgical Equipment Market is expected to reach $12.1 billion by 2020 - Allied Market Research 2Global Surgical Equipment Market is expected to reach $12.1 billion by 2020 - Allied Market Research 3Immunomic Therapeutics Engages Newport Coast Securities, Inc. 2Immunomic Therapeutics Engages Newport Coast Securities, Inc. 3DisasterTalk App Could Save Lives as Report Reveals 8% of US Homes at Very High Risk of Natural Disaster 2Droidles, the Social Network of Robots and Open Source Platform for the Internet of Things, Launches for Crowd Funding on IndieGoGo.com 2
Cached News: