HOME >> BIOLOGY >> NEWS
Sea creature's toxin could lead to promising cancer treatment

tinguishable in its biological action, but is easier to synthesize in the lab.

The researchers tested AB-5's effectiveness against cancer by implanting human tumor cells under the skin of m ice and treating them with either paclitaxel (Taxol) or vinblastine both approved drugs currently used or AB-5. The trial used tumor cells from human prostate, breast and colon cancers.

While all three drugs reduced tumors in the mice, the known drugs caused significant weight loss and loss of white blood cells while AB-5 caused neither side effect. "That the diazonamide toxin blocks mitosis selectively in cancer cells is almost too desirable an outcome to be true," said Dr. Steven McKnight, chairman of biochemistry and senior author of the second study. "As with any other unanticipated scientific discovery, the validity of these observations will be held to appropriately diligent scrutiny."


'"/>

Contact: Aline McKenzie
aline.mckenzie@utsouthwestern.edu
214-648-3404
UT Southwestern Medical Center
5-Feb-2007


Page: 1 2 3

Related biology news :

1. New use for a cell toxin found to inhibit survival proteins in cancer cells
2. Children of smokers have more than 5 times higher levels of a nicotine toxin
3. Genome of Clostridium botulinum reveals the background to worlds deadliest toxin
4. Engineered protein effective against Staphylococcus aureus toxin
5. Anthrax paralyzes immune cells with lethal toxin, UF research shows
6. Gene that governs toxin production in deadly mold found
7. Bacterial response to oxidation studied as toxin barometer
8. Scripps research scientists: Compounds show significant promise against potential bioweapon toxins
9. Algae toxin identification unravels fish-kill mystery
10. Red tide toxins leave beachgoers breathless
11. Study reveals molecular basis of botulism toxins deadly activity

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/16/2017)... Germany , March 16, 2017 CeBIT 2017 - Against identity ... Continue Reading ... Used combined in one project, multi-biometric solutions provide ... Used ... Systems) ...
(Date:3/9/2017)... , Australia , March 9, ... study data at the prestigious World Lung Imaging Workshop ... Andreas Fouras , was invited to deliver the ... pulmonary medicine. This globally recognised event brings together leaders ... share the latest developments in lung imaging. ...
(Date:3/7/2017)... , March 7, 2017 Brandwatch , the ... by The Prince,s Trust to uncover insights to support ... The Trust. The UK,s leading youth charity will be ... campaign results and get a better understanding of the topics and ... ...
Breaking Biology News(10 mins):
(Date:4/25/2017)... ... April 25, 2017 , ... Covalent Metrology ... Analytical Services unit provides high-quality data to clients, both faster and ... of receipt. There are no price premiums, and customers are welcome to participate ...
(Date:4/24/2017)... ... April 24, 2017 , ... ... in a cellular milieu; however, the broad application of this cellular target engagement ... with sensitive quantitative readouts. Cell-based thermal stabilization assays are valuable methods for particular ...
(Date:4/21/2017)... ... 21, 2017 , ... The 2017 Colorado Manufacturing Awards celebrates ... nominees and well as the first-year award for 2017 Manufacturing Women of the ... hosted by CompanyWeek and Manufacturers Edge, among other sponsors. , The Colorado ...
(Date:4/21/2017)... ... April 21, 2017 , ... The ... announced first round funding to three startups through the UConn Innovation Fund. The ... new business startups affiliated with UConn. , The UConn Innovation Fund provides investments ...
Breaking Biology Technology:
Cached News: