HOME >> BIOLOGY >> NEWS
'Sewer gas' induces suspended animation without decreasing blood pressure

VIRGINIA BEACH, VA (October 9, 2006) -- Hydrogen sulfide gas can induce a state of suspended animation in mice while maintaining normal blood pressure, a finding that researchers hope will one day help treat critically-ill patients.

Hydrogen sulfide gas, sometimes called sewer gas, produces a noxious odor often described as a rotten egg smell. The gas occurs naturally in swamps, springs and volcanoes. While usually harmless, it can be toxic if breathed in sufficient quantity, explained Gian Paolo Volpato, one of the study's authors.

The study, entitled "Cardiovascular response to breathing hydrogen sulfide in a murine model: separating the effects of body temperature," will be presented Sunday, Oct. 8, at The American Physiological Society conference, "Comparative Physiology 2006: Integrating Diversity," in Virginia Beach, VA, Oct. 8-11. Gian Paolo Volpato, Robert J. Searles, Marielle Scherrer-Crosbie, Oleg V. Evgenov, Kenneth D. Block, Fumito Ichinose and Warren M. Zapol of the Massachusetts General Hospital in Boston carried out the study.

The research built on a 2005 study from the University of Washington in Seattle and the Fred Hutchinson Cancer Research Center, which found that when mice breathed the gas, they went into a hibernation-like state. Their metabolic rate dropped by 90% and their body temperature decreased to nearly the temperature of the surrounding air.

New research looks at cardiovascular effects

"We wanted to confirm the Seattle study and record the effects the gas has on blood pressure, heart rate, respiratory rate and the activity level of the mice," Volpato explained. They administered 80 parts per million of hydrogen sulfide gas to their mice and found their:

  • heart rate fell from 500 beats per minute to 200 beats per minute
  • respiration rate decreased from 120 breaths to 25 breaths per minute
  • core body temperature fell from 38 C to 30 C
  • activi
    '"/>


Contact: Christine Guilfoy
cguilfoy@the-aps.org
301-634-7253
American Physiological Society
9-Oct-2006


Page: 1 2 3

Related biology news :

1. Antibody retards growth and induces death in liver cancer cells
2. AVN944 inhibits IMPDH and induces apoptosis-related biomarkers in patients with hematologic cancers
3. Reconstructed 1918 influenza virus induces immune response that fails to protect
4. High blood pressure induces low fat metabolism in heart muscle
5. New combination treatment induces regression of prostate cancer
6. Human trial proves ricin vaccine safe, induces neutralizing antibodies; further tests planned
7. Mouse model reveals that oncoprotein induces abnormal preleukemic blood cell progenitors
8. Past experience of pheromones induces dominant courtship behavior in fruit flies
9. Coming soon -- Protein synthesis without amino acids?
10. Research without borders: Head of Santa Fe Institute to address NSF
11. 2-protein team would be lost without each other

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/20/2016)... 20, 2016 Securus Technologies, a leading ... for public safety, investigation, corrections and monitoring announced ... it has secured the final acceptance by all ... Managed Access Systems (MAS) installed. Furthermore, Securus will ... be installed by October, 2016. MAS distinguishes between ...
(Date:6/9/2016)... in attendance control systems is proud to announce the introduction of fingerprint attendance control ... right employees are actually signing in, and to even control the opening of doors. ... ... ... Photo - ...
(Date:6/3/2016)... 3, 2016 Das ... Nepal hat ein 44 ... geprägter Kennzeichen, einschließlich Personalisierung, Registrierung und IT-Infrastruktur, ... Produktion und Implementierung von Identitätsmanagementlösungen. Zahlreiche renommierte ... Januar teilgenommen, aber Decatur wurde als konformste ...
Breaking Biology News(10 mins):
(Date:6/23/2016)... -- The Biodesign Challenge (BDC), a university competition that asks ... systems and biotechnology, announced its winning teams at the ... York City . The teams, chosen ... MoMA,s Celeste Bartos Theater during the daylong summit. Keynote ... of architecture and design, and Suzanne Lee , ...
(Date:6/23/2016)... ... June 23, 2016 , ... ... the launch of the Supplyframe Design Lab . Located in Pasadena, Calif., ... the future of how hardware projects are designed, built and brought to market. ...
(Date:6/23/2016)... ... 23, 2016 , ... In a new case report published today in STEM ... who developed lymphedema after being treated for breast cancer benefitted from an injection of ... dealing with this debilitating, frequent side effect of cancer treatment. , Lymphedema ...
(Date:6/23/2016)... BEACH, Calif. , June 23, 2016  Blueprint ... new biological discoveries to the medical community, has closed ... co-founder Matthew Nunez . "We have ... us with the capital we need to meet our ... will essentially provide us the runway to complete validation ...
Breaking Biology Technology:
Cached News: