"The diversity of organic chemistry, with its harvest of competing, interconnected reactions, becomes an asset rather than a liability in the case of the energy-driven system," explains Shapiro. "The existence of side reaction paths can provide the network with the capacity of reacting to circumstances."
Shapiro outlines how replicator theories, though they have been supported by "prebiotic" syntheses carried out by chemists using modern apparatus and purified reagents, are highly unlikely. The creation of a molecule that can self-replicate requires the combination of diverse chemicals in a long sequence of reactions in a specific order, interspersed by complicated separations, purifications, and changes in locale.
Instead, Shapiro introduces the idea of a "driver" reaction, linked to a free energy source, that helps convert an unorganized mixture into a organized, self-regulated metabolic network.
"If we wish a more plausible origin of life, then we must work with the assumption that life began, somehow, among one of the mixtures of simple organic molecules that are produced by abiotic processes," writes Shapiro. "Nature will be instructing us, rather than we attempting to impose our schemes onto it."
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Contact: Suzanne Wu
swu@press.uchicago.edu
773-834-0386
University of Chicago Press Journals
16-May-2006