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Smallpox outbreak: How long would it take for vaccines to protect people? Would it work?

against smallpox disease with another vaccine called Dryvax, the currently licensed vaccine. The new vaccine will be given either alone or in combination with Dryvax.

"Another purpose of the study is to see how quickly people can be protected against smallpox after a release of smallpox into the environment," Frey said.

Dryvax vaccine is the original Food and Drug Administration (FDA) licensed vaccine that was used to protect humans against smallpox disease. In this study, the Dryvax vaccine is being used as a research vaccine because its use in this study is different than the FDA approved current recommended use of this licensed vaccine.

The Dryvax vaccine is made from a live virus called vaccinia. The only people who presently receive this vaccine are people who work with viruses associated the risk of similar "pox" diseases; these are called by names like vaccinia, orthopox and monkeypox virus. (This group includes some government employees, some emergency workers military personnel and researchers).


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Contact: Joe Muehlenkamp
muehlenk@slu.edu
314-977-8015
Saint Louis University
30-Apr-2007


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