HOME >> BIOLOGY >> NEWS
Smokeless tobacco more effective than cigarettes for delivering dangerous carcinogens into the body

PHILADELPHIA It may not be inhaled into the lungs, but smokeless tobacco exposes users to some of the same potent carcinogens as cigarettes. In the August issue of Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research, researchers at the University of Minnesota Cancer Center report that users of smokeless tobacco are exposed to higher amounts of tobacco-specific nitrosamines -- molecules that are known to be carcinogenic -- than smokers.

Smokeless tobacco, also known as oral snuff, is a variant on chewing tobacco that users suck on by slipping it between their cheeks and gums. In a study comparing 182 oral snuff users with 420 cigarette smokers, the Minnesota researchers found that snuff users were exposed to higher levels of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) than smokers. NNK is a human carcinogen known to produce lung cancer as well as cancers of the pancreas, nasal mucosa and liver in laboratory animals.

Smokeless tobacco products have been proposed by some as safer alternatives to cigarettes, but they are not safe, said author Stephen S. Hecht, Ph.D., professor of cancer prevention at the University of Minnesota Cancer Center. The only likely safe alternative to smoking is the long term use of nicotine replacement therapy as a means to reduce dependence.

In fact, this study lends evidence to support the notion that the oral use of tobacco actually provides a more efficient means for delivering certain carcinogens into the body through the bloodstream, although cigarette smoke includes a host of carcinogenic products that arent a major factor in smokeless tobacco, Hecht said.

The study participants included men and women aged 17 to 80 who had sought but had yet to begin treatment for tobacco addiction, and who used conventional, popular U.S. brands of smokeless tobacco. The researchers studied nitrosamine exposure by analyzing the urine of par
'"/>

Contact: Greg Lester
lester@aacr.org
267-646-0554
American Association for Cancer Research
9-Aug-2007


Page: 1 2

Related biology news :

1. Does the desire to consume alcohol and tobacco come from our genetic makeup?
2. Study confirms the risk of exposure to secondhand tobacco smoke outdoors
3. Race affects tobacco absorption in children
4. Georgetown leads effort to study safety of alternative tobacco products
5. Carcinogens from parents tobacco smoke found in their babies urine
6. Environmental tobacco smoke linked to behavior problems in children and pre-teens
7. Human albumin from tobacco plants
8. UCF, NIH study: Effective, safe anthrax vaccine can be grown in tobacco plants
9. Any exposure to tobacco smoke during pregnancy is risky
10. Developing a more effective vaccine for tuberculosis
11. Cost-effective method for gene silencing is featured in Cold Spring Harbor Protocols

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/6/2019)... ... August 05, 2019 , ... ... to announce its attendance at the Microscopy & Microanalysis 2019 Meeting ( M&M ... the Oregon Convention Center. , The Microscopy & Microanalysis Meeting, organized by the ...
(Date:8/1/2019)... ... August 01, 2019 , ... The GENSPEED platform is a compact, ... It is fully developed with over 100 units deployed in the field for multiple ... use, our collaboration with axiVEND will give us a foothold in the USA to ...
(Date:8/1/2019)... ... July 31, 2019 , ... Advancements with ... local listings for more information. , Factor Bioscience Inc. (Factor) is pioneering nucleic-acid ... and age-related diseases. This segment of Advancements will explore how Factor Bioscience is ...
Breaking Biology News(10 mins):
(Date:6/12/2019)... N.J. (PRWEB) , ... June 12, 2019 , ... ... custom built, helium-based leak testing instruments for the Pharmaceutical, Biotechnology, Medical Device and ... Shanghai Zillion has been signed. The agreement will grant exclusive rights for Zillion ...
(Date:6/11/2019)... REDWOOD CITY, Calif. (PRWEB) , ... June 10, ... ... (IOPP) today announced IOPP will add 80 of its scientific journals to ... addition of physics-related content to DeepDyve’s continually expanding library of more than 20 ...
(Date:6/11/2019)... ... June 11, 2019 , ... A study released today in ... are able to incorporate into human CD34+ cells, modifying their gene expression and ... increased the cells’ ability to lodge into bone marrow. This research performed by ...
(Date:5/31/2019)... (PRWEB) , ... May 29, ... ... our patent applications from the USPTO providing proprietary interest to our methodology, ... FOR SLEEP DISORDER DIAGNOSIS AND TREATMENT… extends Somnology’s IP rights including our ...
Breaking Biology Technology:
Cached News: