HOME >> BIOLOGY >> NEWS
Sperm proteome gives 'tantalizing glimpse' towards the origin of sex

The first ever catalogue of the different types of proteins found in sperm could help reveal the origins of sex and explain some of the mysteries of infertility, say scientists.

Research published in Nature Genetics today describes 381 proteins present in sperm of the fruit fly, Drosophila melanogaster. Whilst more proteins may be identified as research progresses, this study marks the first substantial 'whole-cell' characterisation of the protein components of a higher eukaryotic cell (a cell in which all the genetic components are contained within a nucleus).

This so-called 'proteome' contains everything the sperm needs to survive and function correctly, and scientists can use it to investigate the factors that make some sperm more successful than others.

Around half of the genes of the fruit fly sperm proteome have comparable versions in humans and mice, making it a useful model for studying male infertility in mammals.

By comparing the sperm proteome of the fruit fly with other species, scientists will also be able to rewind evolution and work out the core sperm proteome the most basic constituents a sperm needs for sexual reproduction. This will shed light on how sex itself evolved.

"This is the first catalogue of sperm proteins for any organism, and it offers a tantalising glimpse into how we might begin to answer some of biology's most fundamental questions," said Dr Tim Karr from the University of Bath who led the study.

"Amazingly we know very little about what is in a sperm, which probably explains why we don't really understand sex, let alone how it evolved.

"Before we catalogued the sperm proteome, we only knew a few specific proteins in the Drosophila sperm.

"Being able to compare the structure and content of the proteomes of sperm from different species should help us understand the evolution and origin of sperm.

"We now know of at least 381, which is a grea
'"/>

Contact: Andrew McLaughlin
a.mclaughlin@bath.ac.uk
44-012-253-86883
University of Bath
12-Nov-2006


Page: 1 2 3

Related biology news :

1. Sperm created in the laboratory from embryonic stem cells produce viable progeny
2. Sperm stem cells closer to being like embryonic stem cells
3. Sperm trading can resolve hermaphrodite mating conflicts
4. Sperm enzyme is essential for male fertility, study shows
5. Protein structures for the entire yeast proteome
6. MicroRNAs, alternative splicing and the muscle proteome
7. Plague proteome reveals proteins linked to infection
8. Scientists characterize proteome of human cornea
9. NIH gives $8M to University of Pittsburgh School of Medicine for myositis research
10. Brain blood flow gives clues to treating depression
11. Immune system escape hatch gives cancer cells traction

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/22/2016)... 22, 2016  The American College of Medical Genetics and ... Magazine as one of the fastest-growing trade shows during ... the Bellagio in Las Vegas . ... of growth in each of the following categories: net square ... number of attendees. The 2015 ACMG Annual Meeting was ranked ...
(Date:6/22/2016)... June 22, 2016   Acuant , ... verification solutions, has partnered with RightCrowd ® ... for Visitor Management, Self-Service Kiosks and Continuous ... that add functional enhancements to existing physical ... and venues with an automated ID verification ...
(Date:6/22/2016)... 2016 On Monday, the Department of Homeland ... share solutions for the Biometric Exit Program. The Request ... Protection (CBP), explains that CBP intends to add biometrics ... the United States , in order to deter ... Logo - http://photos.prnewswire.com/prnh/20160622/382209LOGO ...
Breaking Biology News(10 mins):
(Date:6/24/2016)... ... 2016 , ... Researchers at the Universita Politecnica delle Marche in Ancona combed ... pleural mesothelioma. Their findings are the subject of a new article on the Surviving ... signposts in the blood, lung fluid or tissue of mesothelioma patients that can help ...
(Date:6/23/2016)... A person commits a crime, and the detective ... the criminal down. An outbreak of foodborne illness ... (FDA) uses DNA evidence to track down the bacteria that ... It,s not. The FDA has increasingly used a complex, cutting-edge ... illnesses. Put as simply as possible, whole genome sequencing is ...
(Date:6/23/2016)... SAN FRANCISCO , June 23, 2016   ... it has secured $1 million in debt financing from ... to ramp up automation and to advance its drug ... for its new facility. "SVB has been ... goes beyond the services a traditional bank would provide," ...
(Date:6/23/2016)... NEWPORT BEACH, Calif. , June 23, 2016 /PRNewswire/ ... offering new biological discoveries to the medical community, has ... and co-founder Matthew Nunez . "We ... provide us with the capital we need to meet ... funding will essentially provide us the runway to complete ...
Breaking Biology Technology:
Cached News: