Standardized microarrays may bring us one step closer

A new study by 64 renowned scientists may bring us one step closer to personalized medical treatment--that is, medical treatment tailored to each person's unique genetic make-up and medical condition. The study shows researchers how to get more consistent and reliable results when using a technology called microarrays or gene chips. Microarrays allow scientists to see how differences in gene expression are linked to specific diseases. Improving and standardizing microarray experiments will also allow earlier detection of diseases like cancer.

"The microarray is fairly new so, right now, researchers are using a lot of different methods and protocols in microarray experiments. That makes it hard for researchers to compare their results to results from other labs," said Kenneth Olden, Ph.D., Director of the National Institute of Environmental Health Sciences (NIEHS). "When scientists start using the same methods, equipment and reagents, data can be compared across the entire field of medicine and scientific advances will come more quickly."

The study, conducted by the Toxicogenomics Research Consortium, which is funded by the National Institute of Environmental Health Sciences, part of the National Institutes of Health, was initiated in 2001 to asses what causes variation in gene expression experiments within and between labs, as well as within and between microarray platforms. The TRC is a consortium of 7 research centers including: NIEHS Microarray Group of the National Center for Toxicogenomics, Duke University, Fred Hutchinson Cancer Research Center/University of Washington, Massachusetts Institute of Technology, Oregon Health and Sciences University, and University of North Carolina at Chapel Hill. Icoria Inc. was also a research partner. The paper appears in the May issue of Nature Methods.

The researchers systematically examined the processes involved in most microarray or gene expression studies, and found that using a standardized

Contact: Robin Mackar
NIH/National Institute of Environmental Health Sciences

Page: 1 2 3

Related biology news :

1. Standardized house dust aids health researchers
2. Carnegie Mellon U. transforms DNA microarrays with standard Internet communications tool
3. MIT study: Maturity brings richer memories
4. Variant CJD -- Prion amplification breakthrough brings new insights and hopes for a blood test
5. Extracting eggs from pre-pubertal cancer patients brings hope for future fertility
6. Discovery could help bring down price of DNA sequencing
7. US conservation efforts bring more marine turtles to UK
8. US conservation efforts bring more marine turtles to UK
9. Swell gel could bring relief to back pain sufferers
10. Dilbert of academia brings humor to talk at UH
11. Disorderly protein brings order to cell division

Post Your Comments:

(Date:6/9/2016)... Finland , June 9, 2016 ... National Police deploy Teleste,s video security solution to ensure the ... France during the major tournament ... data communications systems and services, announced today that its video ... Prefecture to back up public safety across the ...
(Date:6/2/2016)... June 2, 2016 The Department of ... awarded the 44 million US Dollar project, for the ... Plates including Personalization, Enrolment, and IT Infrastructure , ... the production and implementation of Identity Management Solutions. Numerous renowned ... Decatur was selected for the most ...
(Date:6/1/2016)... , June 1, 2016 ... in Election Administration and Criminal Identification to Boost Global ... a recently released TechSci Research report, " Global Biometrics ... Region, Competition Forecast and Opportunities, 2011 - 2021", the ... billion by 2021, on account of growing security concerns ...
Breaking Biology News(10 mins):
(Date:6/23/2016)... June 23, 2016 A person commits a crime, ... scene to track the criminal down. An outbreak ... and Drug Administration (FDA) uses DNA evidence to track down ... Sound far-fetched? It,s not. The FDA has increasingly used ... investigations of foodborne illnesses. Put as simply as possible, whole ...
(Date:6/23/2016)... -- The Biodesign Challenge (BDC), a university competition that asks ... systems and biotechnology, announced its winning teams at the ... York City . The teams, chosen ... MoMA,s Celeste Bartos Theater during the daylong summit. Keynote ... of architecture and design, and Suzanne Lee , ...
(Date:6/23/2016)... ... June 23, 2016 , ... In a new case report published ... how a patient who developed lymphedema after being treated for breast cancer benefitted from ... the paradigm for dealing with this debilitating, frequent side effect of cancer treatment. ...
(Date:6/23/2016)... -- On Wednesday, June 22, 2016, the NASDAQ ... Dow Jones Industrial Average edged 0.27% lower to finish at ... Stock-Callers.com has initiated coverage on the following equities: Infinity Pharmaceuticals ... NKTR ), Aralez Pharmaceuticals Inc. (NASDAQ: ARLZ ... Learn more about these stocks by accessing their free trade ...
Breaking Biology Technology:
Cached News: