HOME >> BIOLOGY >> NEWS
Stanford/Packard scientist's data-mining technique strikes genetic gold

A new method to mine existing scientific data may provide a wealth of information about the interactions among genes, the environment and biological processes, say researchers at the Stanford University School of Medicine, Lucile Packard Children's Hospital and Harvard Medical School. Like panning for gold, they used the powerful technique to sift through millions of bits of unrelated information - in this case, gene expression data from so-called microarray experiments - to pinpoint genes likely to be involved in leukemia, aging, injury and muscle development.

"This is just the tip of the iceberg," said bioinformatics specialist Atul Butte, MD, PhD, who is also a pediatrician at Lucile Packard Children's Hospital at Stanford. "Nearly 100 different diseases have been studied using microarrays, spanning all of medicine. This is a new way to explore this type of data. We can study virtually everything that's been studied." Butte is the first author of the study, which is published in the Jan. 6 online issue of Nature Biotechnology.

The advance comes with a caveat, however: clinically useful nuggets will be buried under the avalanche of data inundating international repositories each year unless scientists come up with a way to better classify their experiments and results.

"Libraries figured out a long time ago how to classify items using the Dewey decimal and other systems," said Butte, who estimates that the contents of the databases are more than doubling each year. "We need to write software now that will help scientists assign the proper concepts to each experiment."

Microarray experiments allow researchers to compare the expression patterns of tens of thousands of individual genes over time in diseased and healthy cells, or in many other experimental conditions. Each experiment generates thousands of pieces of data about the cell's genes. Although biologists use the technology routinely, focusing only on the few result
'"/>

Contact: Krista Conger
kristac@stanford.edu
650-725-5371
Stanford University Medical Center
10-Jan-2006


Page: 1 2 3

Related biology news :

1. New Down syndrome gene identified by Stanford/Packard scientists
2. Jefferson scientists patent dramatically improves
3. American scientists research of lifes first cells
4. Good times ahead for dinosaur hunters, according to U of Penn scientists dinosaur census
5. FSU scientists biomolecular research published in Science, Nature
6. AAAS honors scientists commitment to justice for workers and scientific integrity in public policy
7. Turkish scientists discovery of how proteins work
8. Internet data-mining of natural history
9. Innovative tagging technique may help researchers better protect fish stocks
10. Innovative research technique reveals another natural wonder in Yellowstone Park
11. New techniques redefine assessment of liver disease

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:7/18/2020)... ... July 16, 2020 , ... A study has ... Invictus Medical Neoasis™ active noise control device to attenuate typical noises in a ... device attenuated the alarm sounds from patient monitors, ventilators and other bedside devices ...
(Date:7/10/2020)... ... July 08, 2020 , ... Overcoming Comparability ... Regulation, An FDAnews Webinar, Wednesday, July 22, 2020 • 1:30 p.m.-3:00 p.m. EDT, ... is the most effective way to complete one? Will the study comply with ...
(Date:7/4/2020)... ... July 03, 2020 , ... ... earn outstanding recognition and multiple awards for not only the products and treatments ... SoME® Skincare and Vivace® Microneedle RF. All the brands built by ABM have ...
Breaking Biology News(10 mins):
(Date:7/10/2020)... , ... July 08, 2020 , ... ... and products, announces a significant expansion of laboratory operations through its COVID-19 ... agencies implementing testing programs. , Bode-CARES provides a turnkey solution ...
(Date:7/10/2020)... LEXINGTON, Mass. (PRWEB) , ... July 09, 2020 ... ... novel approaches to cell therapy, today announced the hiring of Allen R. Nissenson, ... executive team and oversee the clinical development of Sentien’s lead product, SBI-101. ...
(Date:7/1/2020)... (PRWEB) , ... June 29, 2020 , ... ... year to date growth of 40% in 2020, despite many obstacles created as ... MedShift aims to increase revenue for its partnered medical practices and medical manufacturers ...
(Date:6/28/2020)... NIGUEL, Calif. (PRWEB) , ... June 25, 2020 , ... ... announced the launch of Safe Space™ for businesses of all types to ensure cleanliness, ... 3D LiDAR. , A Safe Space™ enabled business will provide a health ...
Breaking Biology Technology:
Cached News: