Stowers scientists clarify role of tumor suppressor gene

provide effective leukemia treatment without adversely affecting normal stem cells."

"Stem cells hold great promise for the treatment of many human diseases," said Robb Krumlauf, Ph.D., Scientific Director. "But the body's limited supply of adult stem cells and our current inability to expand stem cells outside of the body have created major bottlenecks in developing practical therapies. These findings, paired with Dr. Li's earlier work, are bringing us closer to translating this research into long-awaited therapies."

Additional contributing authors from the Stowers Institute include Justin Grindley, Ph.D., Senior Research Associate; Tong Yin, Ph.D., Postdoctoral Research Associate; Sachintha Jayasinghe, Laboratory Manager I; Cici He, Research Specialist II; Jason Ross, Predoctoral Researcher; Jeffrey Haug, Managing Director - Cytometry Facility; Dawn Rupp, Research Technician II; Kimberly Porter-Westpfahl, Research Technician I; Leanne Wiedemann, Ph.D., Staff Scientist. Hong Wu, Ph.D. at University of California at Los Angeles also contributed to the article.

"This publication was a true cooperative effort, which would not have been possible without the contributions of Drs. Grindley, He, and Yin, and the members of the Cytometry core facility," said Dr. Li. "No single person can take credit for these findings, so we're very fortunate to have such a dedicated team of collaborators here at the Stowers Institute."


Contact: Marie Jennings
Stowers Institute for Medical Research

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