HOME >> BIOLOGY >> NEWS
Stress and nerve cells survival in rats; finding may open window for depression treatment

WASHINGTON, DC March 9, 2007 A single, socially stressful situation can kill off new nerve cells in the brain region that processes learning, memory, and emotion, and possibly contribute to depression, new animal research shows.

Researchers found that in young rats, the stress of encountering aggressive, older rats did not stop the generation of new nerve cellsthe first step in the process of neurogenesis. But stress did prevent the cells, located in the hippocampus, from surviving, leaving fewer new neurons for processing feelings and emotions. The hippocampus is one of two regions of the brain that continues to develop new nerve cells throughout life, in both rats and humans. The reduction of neurogenesis could be one cause of depression, says senior author Daniel Peterson, PhD, of the Rosalind Franklin University of Medicine and Science, near Chicago. His team reports their findings in the March 14 issue of The Journal of Neuroscience.

"This is strong evidence that the effects of social stress on neurogenesis occur after a delay of 24 hours or more, providing a possible time window for treatment after acute episodes of stress," says Henriette van Praag, PhD, of the Salk Institute for Biological Studies.

When Peterson and his research team put a young rat in a cage with two older rats for 20 minutes, the resident rats quickly pinned down and, in many cases, bit the intruder. The team reported that intruder rats were fearful and acted depressed around the bigger, more mature animals and had stress hormone levels six times as high as young rats that didn't experience a stressful encounter.

Examining the rats' brains under a microscope, the scientists discovered that even with high levels of stress hormones, the young, stressed rats generated as many new cells as their unstressed counterparts. Previous research had led some to think that hormone levels played a role in blocking the generation of new cells or caused
'"/>

Contact: Sara Harris
sharris@sfn.org
202-962-4000
Society for Neuroscience
13-Mar-2007


Page: 1 2

Related biology news :

1. Stressed-out African naked mole-rats may provide clues about human infertility
2. Stress hormones may play new role in speeding up cancer growth
3. Stress and the city: Urban birds keep cool
4. Stress imaging tests predict prognosis of heart disease in obese persons
5. Stress-induced levels of corticotropin-releasing factor responsible for binge behaviour
6. Stress interferes with problem-solving; Beta-blocker may help
7. Stressed cells spark DNA repair missteps and speed evolution
8. Stress, mood and other factors may affect moms diet during pregnancy
9. Stress impairs thinking via mania-linked enzyme
10. Natures weapon against nerve agents
11. Autism-related proteins control nerve excitability, researchers find

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:7/17/2019)... ... July 16, 2019 , ... Imagine using a simple, portable test ... loss before it causes osteoporosis. For South Dakota School of Mines & Technology researcher ... game-changer in terms of our ability to monitor and prevent disease,” says Wang. ...
(Date:7/9/2019)... ... July 08, 2019 , ... On June 27, ... of the innovation behind two Danisco amylase patent applications (EP2859097 and EP2825643). The ... on prior art was without merit and awarded costs to Danisco. , ...
(Date:6/20/2019)... (PRWEB) , ... June 19, 2019 , ... ... announced by the Infectious Diseases Society of America Foundation, and the possibly millions ... Aging to study infectious agents in AD, are a “welcome affirmation” of the ...
Breaking Biology News(10 mins):
(Date:5/31/2019)... ... May 30, 2019 , ... Object Pharma, Inc., a ... acquisition of Metabiologics, Inc., a globally recognized leader in the production and sale ... rights to a full spectrum of botulinum neurotoxins, as well as a CDC ...
(Date:5/15/2019)... , ... May 15, 2019 , ... Milton Hershey School® ... recognition for his work within the biomedical industry, where he is changing lives by ... devices. , “William Harding epitomizes the vision of our founders – Milton and ...
(Date:5/8/2019)... ... May 07, 2019 , ... Standing at 16.2 hands, Atlas is on the large ... a drill team and barrel racing, among other activities. When loping around a corner ... went from being a busy horse to only being able to walk. Fortunately Atlas’ ...
(Date:5/2/2019)... ... April 30, 2019 , ... ... ISO 9001:2015 standard, REPROCELL USA Inc. has demonstrated its ability to provide ... USA Inc. aims to enhance customer satisfaction through the effective implementation of ...
Breaking Biology Technology:
Cached News: