HOME >> BIOLOGY >> NEWS
Stuck on you: CEACAM6 helps E. coli stick to intestinal lining in Crohn's disease

In Crohn's disease, the lining of the small intestine is abnormally colonized by E. coli organisms that are able to adhere to and invade intestinal epithelial cells. In a study appearing online on May 24 in advance of publication in the June print issue of the Journal of Clinical Investigation, Arlette Darfeuille-Michaud and colleagues from Universit d'Auvergne, France, show that the adherent-invasive E. coli (AIEC) adhere to a region of intestinal epithelial cells known as the brush border in patients with Crohn's disease, but not in healthy individuals. They show that this adhesion is dependent on the expression of the receptor CEACAM6 (carcinoembryonic antigenrelated cell adhesion molecule 6) on the surface of the epithelial cells. They go on to show that CEACAM6 expression is increased in Crohn's disease patients after infection with AIEC bacteria, indicating that this organism can promote its own colonization in individuals with Crohn's disease. The authors conclude that CEACAM6 expression in individuals with inflammatory bowel disease could be used as a diagnostic marker for Crohn's disease.


'"/>

Contact: Brooke Grindlinger
press_releases@the-jci.org
212-342-9006
Journal of Clinical Investigation
24-May-2007


Page: 1

Related biology news :

1. Genetic variation helps to understand predisposition to schizophrenia
2. Link between sunspots, rain helps predict disease in east Africa
3. Taking a supplement of glycine helps prevent degenerative diseases such as arthrosis or osteoporosis
4. Progesterone therapy and preterm birth: More evidence helps identify women who can benefit
5. Nanotechnology helps scientists make bendy sensors for hydrogen vehicles
6. Preconditioning helps protect brains blood vessels from stroke
7. Manchester University helps with pharaoh DNA analysis
8. A spoonful of sugar helps your waistline go down
9. Study helps preserve Arctic whale, Eskimo subsistence hunt
10. Ethanol injection helps manage bone metastasis in thyroid cancer patients
11. Fusing imaging technologies creates synergy, helps diagnose heart disease accurately

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/23/2017)... , May 23, 2017  Hunova, the first robotic gym for the ... been officially launched in Genoa, Italy . The first ... and the USA . The technology was developed ... market by the IIT spin-off Movendo Technology thanks to a 10 million ... News Release, please click: ...
(Date:5/6/2017)... , May 5, 2017 RAM ... announced a new breakthrough in biometric authentication based ... quantum mechanical properties to perform biometric authentication. These new ... semiconductor material created by Ram Group and its ... entertainment, transportation, supply chains and security. Ram Group ...
(Date:4/18/2017)... Inc., a global expert in SoC-based imaging and computing solutions, has ... features the company,s hybrid codec technology. A demonstration utilizing TeraFaces ® ... be showcased during the upcoming Medtec Japan at Tokyo Big Sight ... Las Vegas Convention Center April 24-27. ... Click here for an image of the ...
Breaking Biology News(10 mins):
(Date:10/10/2017)... (PRWEB) , ... October 10, 2017 , ... ... innovation and business process optimization firm for the life sciences and healthcare industries, ... conference in San Francisco. , The presentation, “Automating GxP Validation for Agile ...
(Date:10/9/2017)... Charlotte, N.C. (PRWEB) , ... October 09, 2017 , ... ... Purple announced Dr. Christopher Stubbs, a professor in Harvard University’s Departments of Physics and ... Dr. Stubbs was a member of the winning team for the 2015 Breakthrough Prize ...
(Date:10/7/2017)... (PRWEB) , ... October 06, ... ... leader in Hi-C-based genomic technologies, launched its ProxiMeta™ Hi-C metagenome deconvolution product, ... Hi-C kit and accompanying cloud-based bioinformatics software to perform Hi-C metagenome deconvolution ...
(Date:10/5/2017)... YORBA LINDA, CA (PRWEB) , ... October 05, 2017 , ... ... tech innovators, engineers, and scientists from around the world, is giving back to cancer ... shirt sold in October. , Now through October 31, shoppers can use promo ...
Breaking Biology Technology:
Cached News: