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Studies force new view on biology of flavonoids

goals in prevention of heart disease.

Both of these protective mechanisms could be long-lasting compared to antioxidants, which are more readily used up during their free radical scavenging activity and require constant replenishment through diet, scientists say.

However, Frei said, its also true that such mechanisms require only relatively small amounts of flavonoids to trigger them conceptually, its a little like a vaccine in which only a very small amount of an offending substance is required to trigger a much larger metabolic response. Because of this, there would be no benefit and possibly some risk to taking dietary supplements that might inject large amounts of substances the body essentially sees as undesirable foreign compounds.

Numerous studies in the United States and Europe have documented a relationship between adequate dietary intake of flavonoid-rich foods, mostly fruits and vegetables, and protection against heart disease, cancer and neurodegenerative disease, Frei said.


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Contact: Balz Frei
balz.frei@oregonstate.edu
541-737-5078
Oregon State University
5-Mar-2007


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