HOME >> BIOLOGY >> NEWS
Study finds gender differences in renal and other genes contributing to blood pressure

cent statistical power to detect genes contributing as little as three percent to blood pressure variation. The research team also scored over 60,000 genotypes at 35 gene locations involved in two major pathways regulating blood pressure, kidney or adrenergic or regulation. The genotyping was confined to the top and bottom fifth percentile participants.

Results

The researchers found significant differences in genetic contributors to blood pressure in males versus females. For example, common genetic variants of the b1-adrenergic and 2A adrenergic receptor genes contributed to blood pressure (BP) variation in females while variants at the 2 adrenergic receptor and angiotensinogen genes contributed to BP variation in males.

Conclusion

The researchers leveraged the power of using the extremes (highs and lows) of a trait (blood pressure) measured in a large community-based population with the strategy of assessing genetic variants of genes involved in two major blood pressure regulation pathways to identify gender differences in genetic contribution to blood pressure. The results reinforce previous observations of the role of gender in cardiovascular traits and imply that the development of genetic diagnostic and therapeutic indices for hypertension must take gender into account to provide an accurate assessment and treatment of hypertension.


'"/>

Contact: Donna Krupa
dkrupa@the-aps.org
301-634-7209
American Physiological Society
8-Aug-2007


Page: 1 2

Related biology news :

1. Study begins to reveal clues to the cause and progression of sepsis
2. Study suggests estrogen deficiency can lead to obesity-induced high blood pressure after menopause
3. Study: Sticking to the sand might not be such good, clean fun for beachgoers
4. Study points to new way to predict death risk from torn aorta
5. Study identifies new gene therapy tools for inherited blindness
6. Study finds contaminated water reaching Floridas offshore keys
7. Study sheds light on why humans walk on two legs
8. Study explains how pathogens evolve to escape detection
9. Study finds hereditary link to premenstrual depression
10. Study identifies energy efficiency as reason for evolution of upright walking
11. Study shows cane sugar, corn sweeteners have similar effects on appetite

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/19/2019)... ... 2019 , ... The Laser Institute (LIA)'s 38th ... held in Orlando, Florida and featured the conference’s many firsts. A meeting of ... with a deeper industry foci, more expansive technical sessions, and a new Business ...
(Date:10/17/2019)... , ... October 15, 2019 , ... ... Media for the Microbiological Community”. , Microbiology International currently manufactures ready-to-use culture broth ... also offers pre-poured agar plates & liquid supplements. , This major step underpins ...
(Date:10/17/2019)... ... October 16, 2019 , ... The International Society for ... Baseline® Guide: Water and Steam Systems (Third Edition) . This guide provides in-depth ... systems. Industry professionals can better understand Good Manufacturing Practices (GMPs), to comply with ...
Breaking Biology News(10 mins):
(Date:10/3/2019)... ... October 02, 2019 , ... Today marked the ... is enabling clinical program outsourcing success by cultivating radical improvements in leadership, staff, ... veteran executive Brenda Reese, phaseUP™ brings clients deep, broad and unique expertise in ...
(Date:10/3/2019)... ... 03, 2019 , ... Yesterday, at the 2019 meeting of Outsourcing in Clinical ... L. Sherley, M.D., Ph.D., discussed important design factors that currently limit the success of ... and suppliers of clinical trials, in his talk Dr. Sherley focused on ...
(Date:9/24/2019)... N.J. and WALTHAM, Mass. (PRWEB) , ... ... ... Catalent, the leading global provider of advanced delivery technologies, development, and manufacturing ... Neurosciences, Inc. (NASDAQ: NERV), a clinical-stage biopharmaceutical company focused on the development ...
(Date:9/22/2019)... Ore. (PRWEB) , ... September 20, 2019 , ... ... commercial launch of Brain-Derived Neurotrophic Factor (BDNF) testing in serum . BDNF ... nervous systems. BDNF stimulates the growth and differentiation of new neurons in the ...
Breaking Biology Technology:
Cached News: