Study finds obesity is associated with an impairment of coronary circulator...( t of the heart vessels that may precede...)

t of the heart vessels that may precede morphological changes in the further course of the development of coronary artery disease," said Schindler. PET imaging may identify overweight/obese individuals with normal SPECT imaging results, but at increased risk for the progression of coronary artery disease and future cardiovascular events, he explained.

"This scientific finding is one of a continuing series of studies from UCLA documenting impaired vascular reactivity in relation to hypertension, diabetes, hypercholesterolemia, smoking and obesity," said Josef Machac, M.D., director of the Clinical PET Center and Nuclear Medicine at Mount Sinai School of Medicine, New York, N.Y., and a vice chair of SNM's Scientific Program Committee (Cardiovascular Track).

The authors of "Obesity Is Associated With an Impairment of Coronary Circulatory Function" are Thomas H. Schindler, Jerson Cadenas, Michael Kreissl, Xiao-Li Zhang and Heinrich R. Schelbert, Department of Molecular and Medical Pharmacology, David Geffen School of Medicine at UCLA, Los Angeles, Calif.

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Contact: Maryann Verrillo
mverrillo@snm.org
703-708-9000
Society of Nuclear Medicine
20-Jun-2005

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