HOME >> BIOLOGY >> NEWS
Study identifies target for preventing sexual transmission of HIV

ze the CCR5 receptor so HIV cannot bind to it. We developed an altered RANTES molecule, called PSC-RANTES, that is thousands of times more effective than RANTES at targeting CCR5 making it unavailable to the virus."

In their experiment, Dr. Lederman and his colleagues applied a highly concentrated solution containing the altered chemokine to the vaginal membranes of rhesus macaque monkeys and challenged them with high doses of a virus that combined the outer surface of HIV and the inner workings of SIV so called SHIV. The solution was successful in protecting the macaques without any detectable side effects.

"There is still a lot of work to be done before we have an affordable, easy to use method of blocking transmission of HIV through the vaginal membranes," Dr. Lederman said. "But we have taken an important step. Now that we have shown that it is possible to block SHIV transmission through the vagina in macaques and have identified the target molecule for blocking that transmission, the door is open to the development of a topical agent that could prevent infection with HIV in humans."


'"/>

Contact: George Stamatis
george.stamatis@case.edu
216-368-3635
American Medical Association
14-Oct-2004


Page: 1 2

Related biology news :

1. Study begins to reveal clues to the cause and progression of sepsis
2. Study finds gender differences in renal and other genes contributing to blood pressure
3. Study suggests estrogen deficiency can lead to obesity-induced high blood pressure after menopause
4. Study: Sticking to the sand might not be such good, clean fun for beachgoers
5. Study points to new way to predict death risk from torn aorta
6. Study identifies new gene therapy tools for inherited blindness
7. Study finds contaminated water reaching Floridas offshore keys
8. Study sheds light on why humans walk on two legs
9. Study explains how pathogens evolve to escape detection
10. Study finds hereditary link to premenstrual depression
11. Study identifies energy efficiency as reason for evolution of upright walking

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Study identifies target for preventing sexual transmission HIV

(Date:6/19/2013)... across the Midwest are expected to contribute to a ... "dead zone," according to a University of Michigan ecologist ... with one for the Chesapeake Bay. , The Gulf ... and Atmospheric Administration, calls for an oxygen-depleted, or hypoxic, ... would place it among the 10 largest on record. ...
(Date:6/18/2013)... June 19, 2013  Paris Air Show – ... Test Systems) , a leading provider of innovative ... is demonstrating its solutions this week at the ... With growing challenges including increasingly complex armament systems ... feature-rich, specialized aerospace test solutions that address legacy ...
(Date:6/18/2013)... UT Arlington environmental engineer has been awarded a ... to ensure water quality and flow in the ... , Andrew Kruzic, UT Arlington associate professor of ... locations to add monochloramine to the water in ... new pump stations and pipelines. Adding monochloramine is ...
Breaking Biology News(10 mins):U-M researcher and colleagues predict possible record-setting Gulf of Mexico 'dead zone' 2U-M researcher and colleagues predict possible record-setting Gulf of Mexico 'dead zone' 3U-M researcher and colleagues predict possible record-setting Gulf of Mexico 'dead zone' 4Marvin Test Solutions Demonstrates Next-Generation Armament Test Solutions at Paris Air Show 2Marvin Test Solutions Demonstrates Next-Generation Armament Test Solutions at Paris Air Show 3UT Arlington research to benefit quality, flow in 150-mile Integrated Pipeline 2
(Date:6/18/2013)... 18, 2013 The Pistoia ... the HELM biomolecular representation standard software toolkit and ... HELM (Hierarchical Editing Language for Macromolecules) ... biomolecules (e.g. proteins, nucleotides, antibody drug conjugates) whose ... informatics methodologies impractical or unusable. HELM solves this ...
(Date:6/18/2013)... , June 18, 2013 ... international investment research firm, announces the initiation ... a French biopharmaceutical company developing and marketing ... care indications.      (Logo: http://photos.prnewswire.com/prnh/20130417/608168) ... comprehensive report examining the investment merits of ...
(Date:6/18/2013)... -- The "Bioinformatics Market By Sector (Molecular Medicine, Agriculture, ... Data Analysis Services) & Application (Genomics, Proteomics & Drug Design) - Global ... Restraints, and Opportunities in North America , ... and Rest of World. Browse , ... Figures 364 Pages and an in-depth ...
(Date:6/18/2013)... , June 18, 2013  Techne Corporation (NASDAQ: ... it has agreed to acquire 100% ownership of ... Inc. (Bionostics).  Bionostics is a global leader in ... that verify the proper operation of in ... point of care blood glucose and blood gas ...
Breaking Biology Technology:The Pistoia Alliance Releases HELM Biomolecular Representation Standard Open Source Tools 2Edison Expands French Healthcare Sector Coverage With Initiation of Coverage on BioAlliance Pharma 2Edison Expands French Healthcare Sector Coverage With Initiation of Coverage on BioAlliance Pharma 3Bioinformatics Market Worth $7.5 Billion by 2017 2Bioinformatics Market Worth $7.5 Billion by 2017 3Techne Corporation Announces Acquisition Agreement 2Techne Corporation Announces Acquisition Agreement 3Techne Corporation Announces Acquisition Agreement 4Techne Corporation Announces Acquisition Agreement 5
Cached News: