HOME >> BIOLOGY >> NEWS
Study points to new way to predict death risk from torn aorta

ANN ARBOR, Mich. -- Each year, 10,000 Americans suffer a sudden tear in the lining of their bodys largest blood vessel, the aorta. Its often misdiagnosed, and it can kill if not treated immediately. Actor John Ritter died of such a tear in 2003.

Better medical imaging and treatments such as medication, surgery and catheter-based procedures are now giving more patients a chance to survive this crisis, called aortic dissection. But once they leave the hospital, patients face a one-in-four chance of dying within a few years. And doctors dont have a reliable way of predicting who is most at risk of dying, and who might benefit most from surgery or other treatment.

Now, a study published in the July 26 New England Journal of Medicine by an international team of researchers may offer hope for aortic dissection survivors, and give guidance for their physicians. The researchers, led by University of Michigan Cardiovascular Center experts, propose a new way to predict post-hospital death risk for aortic dissection patients, and a new model for the mechanism behind that risk.

Their model focuses on a phenomenon that can easily be seen on modern medical-imaging scans: the presence of blood clots in the channel created when the layers of the aorta separate like two layers of an onion. This channel, called the false lumen, runs alongside the true lumen, which is the hollow middle area of the aorta that acts as the pipeline for blood to flow out of the heart and down through the abdomen.

As blood enters the false lumen from the top of the tear in the aorta, it gets trapped inside the new channel. Often, small openings at the bottom of the newly formed channel will allow the blood to flow out. But if the openings arent large, blood flow inside the false lumen is slowed down, pressure increases, and clots begin to form.

The study shows that the risk of post-hospital death is more than two-and-a-half times greater for patient
'"/>

Contact: Kara Gavin
kegavin@umich.edu
734-764-2220
University of Michigan Health System
25-Jul-2007


Page: 1 2 3 4 5

Related biology news :

1. Study begins to reveal clues to the cause and progression of sepsis
2. Study finds gender differences in renal and other genes contributing to blood pressure
3. Study suggests estrogen deficiency can lead to obesity-induced high blood pressure after menopause
4. Study: Sticking to the sand might not be such good, clean fun for beachgoers
5. Study identifies new gene therapy tools for inherited blindness
6. Study finds contaminated water reaching Floridas offshore keys
7. Study sheds light on why humans walk on two legs
8. Study explains how pathogens evolve to escape detection
9. Study finds hereditary link to premenstrual depression
10. Study identifies energy efficiency as reason for evolution of upright walking
11. Study shows cane sugar, corn sweeteners have similar effects on appetite

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/5/2017)... -- The Allen Institute for Cell Science today announces the ... and dynamic digital window into the human cell. The ... of deep learning to create predictive models of cell ... growing suite of powerful tools. The Allen Cell Explorer ... available resources created and shared by the Allen Institute ...
(Date:3/30/2017)...  On April 6-7, 2017, Sequencing.com will host the ... hackathon at Microsoft,s headquarters in Redmond, Washington ... developing health and wellness apps that provide a unique, ... is the first hackathon for personal genomics and ... in the genomics, tech and health industries are sending ...
(Date:3/27/2017)... March 27, 2017  Catholic Health Services (CHS) ... Systems Society (HIMSS) Analytics for achieving Stage 6 ... sm . In addition, CHS previously earned a ... using an electronic medical record (EMR). ... level of EMR usage in an outpatient setting.  ...
Breaking Biology News(10 mins):
(Date:10/10/2017)... ... October 10, 2017 , ... For the second time in ... STEM Mentoring Award. Representatives of the FirstHand program travelled to Washington, D.C. Tuesday, ... , US2020’s mission is to change the trajectory of STEM education in America ...
(Date:10/10/2017)... Calif. , Oct. 10, 2017 SomaGenics ... from the NIH to develop RealSeq®-SC (Single Cell), expected ... for profiling small RNAs (including microRNAs) from single cells ... Program highlights the need to accelerate development of approaches ... "New techniques for measuring levels ...
(Date:10/9/2017)... 9, 2017  BioTech Holdings announced today identification ... its ProCell stem cell therapy prevents limb loss ... Company, demonstrated that treatment with ProCell resulted in ... as compared to standard bone marrow stem cell ... in reduction of therapeutic effect.  ...
(Date:10/9/2017)... ... October 09, 2017 , ... ... line of medical marijuana products targeting the needs of consumers who are incorporating ... Kindred takes place in Phoenix, Arizona. , As operators of two successful Valley ...
Breaking Biology Technology:
Cached News: