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Success rates for prostate cancer depend on experience of surgeon

Surgeons performing operations to remove patients prostate glandsthe primary treatment for prostate cancergo through a steep learning curve, according to a study published online July 24 in the Journal of the National Cancer Institute. As the surgeons gain more experience performing the operation, called a radical prostatectomy, the chance that patients prostate cancer will reoccur goes down.

The idea that more experienced surgeons perform more successful surgeries is a widely held belief. But there have been few data to support this idea, and it has not been previously shown whether a surgeons experience makes a large or small difference on their patients outcome.

Andrew Vickers, Ph.D., of Memorial Sloan-Kettering Cancer Center in New York and colleagues analyzed data from 72 surgeons at four institutions and 7,765 of their prostate cancer patients treated with radical prostatectomies between 1987 and 2003. They measured surgeons experience by the number of times they had performed the procedure before each operation.

More surgical experience was associated with a greater likelihood that the patients cancer would not return after their operation. The learning curve for this procedure was very steepthere was dramatic improvement in patient outcomes as surgeons experience increased up to 250 operations, after which increasing experience had little influence on cancer recurrence. Patients treated by inexperienced surgeons (for example, those with 10 prior operations) were nearly 70% more likely to have evidence of recurrence of their prostate cancer within five years than those whose surgeons had performed 250 operations (17.9% vs. 10.7%).

Our findings also have implications for education in surgical oncology. Although the successful practice of surgery necessarily presumes a lifetime of learning, the large number of cases required before the learning curve plateaus suggests the need to expand opportunities for trai
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Contact: Liz Savage
jncimedia@oxfordjournals.org
301-841-1287
Journal of the National Cancer Institute
24-Jul-2007


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