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Successful lung cancer surgery not enough to break nicotine dependence in many smokers

PHILADELPHIA -- A new study has found that close to half of 154 smokers who had surgery to remove early stage lung cancer picked up a cigarette again within 12 months of their potentially curative operation, and more than one-third were smoking at the one year mark. Sixty percent of patients who started smoking again did so within two months of surgery.

The study, led by researchers at Washington University School of Medicine and published in the December issue of Cancer Epidemiology Biomarkers & Prevention, is the first to look at smoking relapse among people who were "forced" to quit due to impending surgery.

"These patients are all addicted, so you cannot assume they will easily change their behavior simply because they have dodged this particular bullet," said the studys lead author, Mark S. Walker, Ph.D., a clinical psychologist and Assistant Professor of Medicine at Washington University. "Their choices are driven by insidious cravings for nicotine."

The investigators found that those smokers who were the last to give up their cigarettes - some on the same day as their operation - and who saw smoking as a pleasurable activity they would have difficulty giving up, were also the first to resume the habit. And they concluded that patients who were able to hold out the longest before they took up a cigarette after surgery were the ones who were most likely not to be smoking in a years time.

"The results suggest that patients who wait until cancer surgery to quit smoking need assistance from the medical community to help them stay away from cigarettes, and that this intervention should begin as soon as possible after treatment," Walker said. No such programs are currently offered to lung cancer surgery patients, he added.

At least seven studies of non-small cell lung cancer patients have shown that many of these patients continue smoking despite the risk, but the rate of relapse ranged from a low of 13 percent
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Contact: Staci Vernick Goldberg
goldberg@aacr.org
215-440-9300
American Association for Cancer Research
11-Dec-2006


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