HOME >> BIOLOGY >> NEWS
Synthetic peptide targets latent papilloma virus infections

Berkeley -- While a newly marketed vaccine promises to drastically reduce human papilloma virus (HPV) infections, the major cause of cervical cancer, a new discovery by University of California, Berkeley, researchers could some day help the millions of people already infected and at constant risk of genital warts and cancer.

One study found that 75 percent of sexually active men and women under 50 have, or have had, an HPV infection, while 10,000 women annually develop cervical cancer, more than 90 percent of which is caused by HPV. Four thousand women die of cervical cancer each year.

Once infected, it's difficult to rid oneself of the virus because it hides as a latent DNA in cells of the epithelial tissue, such as skin and the lining of the vagina and cervix, and spreads as these cells divide.

The UC Berkeley team created a protein fragment, or peptide, that successfully prevents the virus from hitching a ride on a cell's chromosomes as the cell divides. If such a peptide - or more likely, a drug that mimics the action of the peptide - works in the body, it would effectively stop the virus from spreading or generating warts, which can progress to cancer.

"We're optimistic that this will work generally for many different genetic variants of human papilloma virus, though it's too early to say how many of the genotypes of this virus will respond," said Michael Botchan, professor of molecular and cell biology and a faculty affiliate of the UC Berkeley branch of the California Institute for Quantitative Biology (QB3). "The hope is to have one drug that works for all different human virus types."

"The second most preventable cancer in the world, after lung cancer, is cervical cancer, the result of high HPV infection rates in the developing world, in Asia and South America and Africa," he added. "If we can get something to stop HPV replication, it would have a big health impact."

Botchan, post-doctoral fellow Eric
'"/>

Contact: Robert Sanders
rsanders@berkeley.edu
510-643-6998
University of California - Berkeley
2-Jan-2007


Page: 1 2 3 4

Related biology news :

1. Synthetic adhesive mimics sticking powers of gecko and mussel
2. Springer to publish new journal Systems and Synthetic Biology
3. Synthetic molecule causes cancer cells to self-destruct
4. New designer lipid-like peptide with lipid nanostructures for drug delivery systems
5. New NIST reference material for peptide analysis
6. UCLA AIDS Institute researchers find a peptide that encourages HIV infection
7. Therapeutic peptide frees the protein p73 to kill tumor cells
8. Scientists identify 36 genes, 100 neuropeptides in honey bee brains
9. Defense peptide found in primates may block some human HIV transmissions
10. Patent awarded for LSUHSC-developed peptide that blocks lethal toxins of anthrax
11. Targeted drug delivery now possible with pHLIP peptide

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/14/2017)... (NYSE: IBM ) is introducing several innovative partner startups ... collaboration between startups and global businesses, taking place in ... nine startups will showcase the solutions they have built with ... France is one of the ... percent increase in the number of startups created between 2012 ...
(Date:5/16/2017)... 16, 2017   Bridge Patient Portal , ... MD EMR Systems , an electronic medical ... GE, have established a partnership to build an ... the GE Centricity™ products, including Centricity Practice Solution ... These new integrations will allow healthcare delivery ...
(Date:4/19/2017)... New York , April 19, 2017 ... competitive, as its vendor landscape is marked by the ... the market is however held by five major players ... Safran. Together these companies accounted for nearly 61% of ... of the leading companies in the global military biometrics ...
Breaking Biology News(10 mins):
(Date:10/12/2017)... ... October 12, 2017 , ... ... platform specifically designed for life science researchers to analyze and interpret datasets, ... Franklin, who made a major contribution to the discovery of the double-helix ...
(Date:10/11/2017)... ... ... Personal eye wash is a basic first aid supply for any work environment, but most ... you rinse first if a dangerous substance enters both eyes? It’s one less decision, and ... unique dual eye piece. , “Whether its dirt and debris, or an acid or alkali, ...
(Date:10/11/2017)... , Oct. 11, 2017  VMS BioMarketing, a leading ... a nationwide oncology Clinical Nurse Educator (CNE) network, which will ... need for communication among health care professionals to enhance the ... nurses, office staff, and other health care professionals to help ... breast cancer. ...
(Date:10/11/2017)... ... October 11, 2017 , ... ... implantation and pregnancy rates in frozen and fresh in vitro fertilization (IVF) ... and maternal age to IVF success. , After comparing the results from the ...
Breaking Biology Technology:
Cached News: